On Friday 6 March at 19h in “Centre de Cultura Contemporània de Barcelona” (CCCB), Xavier Salvatella, ICREA resea
Rare and orphan but not abandoned by science
A tool developed at IRB Barcelona to be used by the international consortium Pan-Cancer for the analysis of human tumours
Discovery of the genetic fingerprint of aggressive colon tumours
IRB Barcelona takes part in the co-session "Science is Business", a meeting space to explore new co-innovation pathways
Today in the journal Nature Methods, the laboratory headed by ICREA researcher Patrick Aloy, at the Institute for Research in Biomedicine (IRB Barcelona), presents a computational tool tha
About 40–50% of all colorectal patients relapse in the form of metastasis.
The opening presentation will be given by Joan Guinovart, director of IRB Barcelona and will feature the participation of experts, José Ignacio Latorre, professor of Theoretical Physics at the Univ
El Punt AVUI
An article in “El Punt Avui” newspaper mentions the most recent advances made by the Peptides and Proteins Laboratory at IRB Barcelona, headed by Ernest Giralt, also full professor at the UB. This lab has identified several substances capable of transporting drugs across the barrier that protects the brain from infections.
Gaceta Médica i altres mitjans
On Monday, the weekly medical newspaper “Gaceta Médica” reported on the study published in the journal Nature Genetics by the Colorectal Cancer Laboratory at IRB Barcelona, led by ICREA researcher Eduard Batlle.
“El País” has included an article about Spark, the project started by the public-private consortium led by Iproteos, an IRB Barcelona and UB spin-off. IRB Barcelona, CRG, the University of the Basque Country, and the biopharmaceutical company Ascil-Biopharma are also involved in the project.
«98% of the potential therapeutic molecules against diseases of the central nervous system cannot cross the blood-brain barrier. We develop peptides with the capacity to open the doors of the barrier and act as shuttles when attached to a therapeutic molecule.»
«Controlling a biological process from outside is the future of chemistry and opens up promising roads for advancements in pharmacological research.»
More info on this news here.
Felice Alessio Bava
ex PhD student in the Translational Control of Cell Cycle and Differentiation Lab
«We suspected that CPEB1, a protein involved in regulating mRNA translation in the cytoplasm, might also be active in the nucleus and play a role in controlling pre-mRNA processing. We discovered that it affects the alternative generation in the mature mRNA of the 3'-UTR, regions where most of the elements regulating translation in time and space are located.»
More info about this news here.
«Our study highlights the complexity of p38 functions, both in cancer and in the maintenance of normal tissues. It shows why an inhibitor of this molecule could effectively have undesirable side effects. But these do not exclude it from being a target against cancer.»
More on this news here.
Quick facts about IRB
IRB Barcelona has been awarded the "HR Excellence in Research" logo. This recognition reflects the commitment of the Institute to continuously improving its human resources policies in line with the European Charter for Researchers and the Code of Conduct for the Recruitment of Researchers. The award confirms the efforts of the Institute to ensure fair and transparent recruitment and appraisal procedures. Click here for more information.
IRB Barcelona is home to nearly 450 research, technical and support staff from 35 countries who share the common goal of contributing to the advancement of the biomedical sciences through investigator–driven research, and improving quality of life by applying advances in this field.
The convergence of biology, chemistry, and structural and computational biology is unique at IRB Barcelona and opens a strategic window to gain insight into basic molecular processes in health and disease.
Research is conducted by 23 groups organized into 5 interdisciplinary programmes. Each programme includes a diverse faculty of researchers with overlapping scientific interests. The research areas have been structured to be highly interactive, fostering multidisciplinarity by combining modern molecular biology, classical genetics, biochemistry, structural biology, bioinformatics, systems biology, advanced microscopy, and genomic and proteomic approaches.