Speaker: Antoni Castells, MD
Gastroenterology Service, Hospital Clínic
Barcelona, Spain

Poster

Host

Roger Gomis, IRB Barcelona

Friday, 27 June 2008, 12.00h Aula Fèlix Serratosa

Abstract

Lynch syndrome, also known as hereditary non-polyposis colorectal cancer, is the most common form of hereditary colorectal cancer. It is characterized by early onset of colorectal cancer and other extracolonic associated malignancies. This disorder is inherited in an autosomal dominant pattern and is due to mutations in the DNA-mismatch repair genes. The EPICOLON study, a prospective, multicenter, nation-wide, population-based epidemiological project, lead by the Spanish Gastroenterological Association, has contributed to the clinical and molecular characterization of this syndrome.

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