Methodology to Prepare N-Heterocycles Related to Dihydropyridines: Microwave-Assisted Synthesis of Alkyl 4-Arylsubstituted-6-chloro-5-formyl-2-methyl-1,4-dihydropyridine-3-carboxylate and 4-Arylsubstituted-4,7-dihydrofuro[3,4-b]pyridine-2,5(1H,3H)-di
Rodríguez H, Copro J, Suárez M, Martínez-Álvarez R, Martín N, Albericio F.
Molecules (16), 9620-9635 (2011)

Total synthesis of a Depsidomycin analogue by convergent solid phase peptide synthesis and macrolactonization Strategy for antitubercular activity
Narayanaswamy VK, Albericio F, Coodavia YM, Kruger HG, Maguire GEM, Pillaym M, Govender T.
J Pept Sci (17), 683-689 (2011)

Functionalization of Gold Surfaces: Recent Developments and Applications.
Prats-Alfonso E, Albericio F.
J Mater Sci (46), 7643-7648 (2011)

Aspartimide formation in peptide chemistry: occurrence, prevention strategies and the role of N-hydroxylamines.
Subirós-Funosas R, El-Faham A, Albericio F.
Tetrahedron (67), 8595-8606 (2011)

Highly Efficient, Multigram and Enantiopure Synthesis of 2-(2,4
Bruno P, Peña S, Just-Baringo X, Albericio F, Álvarez M.
Org Lett (13), 4648-4651 (2011)

Highly Efficient, Multigram and Enantiopure Synthesis of 2-(2,4
Just-Baringo X, Bruno P, Albericio F, Álvarez M.
Tetrahedron Lett (52), 5435-5437 (2011)

Effect of a Pool of Peptides Isolated from Crotalus durissus terrificus (South American Rattlesnake) Venom on Glucose Levels of Mice Fed on a High-Fat Diet
Martins-Santos MES, Resende RR, Pinto FCH, Soares AM, Marangoni S, Oliveira E, Albericio F, Da Silva SL.
Int J Pept Res Ther (17), 225-230 (2011)

Peptide Coupling Reagents, More than a Letter Soup.
El-Faham A, Albericio F.
Chem Rev (111), 6557-6602 (2011)

Antioxidant and Cytotoxic Activities of Carob Tree Fruit Pulps are Strongly Influenced by Gender and Cultivar.
Custodio L, Fernandes E, Escapa AL, Fajardo A, Aligué R, Albericio F, Neng N, Nogueira JM, Romano A.
J Agr Food Chem, 7005-7012 (59) (2011)

Acridine and quindoline oligomers linked through a 4-aminoproline backbone prefer G-quadruplex structures.
Ferreira R, Artali R, Farrera-Sinfreu J, Albericio F, Royo M, Eritja E, Mazzini S.
Biochim Biophys Acta (1810), 769-776 (2011)

TRPV1 modulators: Structure-activity relationship using a rational combinatorial approach
Zaccaro L, Garcia-Lopez MT, Gonzalez-Muñiz R, Garcia-Martinez C, Ferrer-Montiel A, Albericio F, Royo M.
Bioorgan Med Chem (21), 3541-3545 (2011)

Synthesis and Aminolysis of 2,4-Dinitro Phenyl and 5-Nitro Pyridine N-Hydroxy Oxime Derivatives,
Khattab SN, Hamed EZ, Albericio F, El-Faham A.
B Chem Soc Jpn (84), 633-639 (2011)

Progress on Lamellarins
Pla D, Albericio F, Álvarez M.
Med Chem Commun (2), 689-697 (2011)

A natural peptide and its variants from the processing of Infectious Pancreatic Necrosis Virus (IPNV) display enhanced antimicrobial activity: A novel alternative to control bacterial diseases
Jofré C, Guzmán F, Cárdenas C, Albericio F, Marshall SH.
Peptides (32), 852-858 (2011)

Efficient preparation of alkyl 4-aryl substituted-2-methyl-6-thioxo-1,4,5,6-tetrahydropyridine-3-carboxylates under microwave irradiation conditions
Rodriguez H, Coro J, Martin O, Lam A, Salfrán E, Rodríguez-Salarichs J, Suárez M, Albericio F, Martín N.
Arkivoc, 125-141 (2011)

Phytochemical profile, antioxidant and cytotoxic activities of carob tree (Ceratonia siliqua L.) germ flour extracts.
Custodio L, Fernandes E, Escapa AL, Fajardo A, Aligué R, Albericio F, Neng N, Nogueira JM, Romano A.
Plant Food Hum Nutr (66), 78-84 (2011)

. 4-(4,6-[2,2,2-Trifluoroethoxy]-1,3,5-triazin-2-yl)-4-methylomorpholinium tetrafluoroborate (DFET/ NMM/BF4). Triazine based coupling reagents designed for coupling sterically hindered substrates.
Jastrząbek KG, Subiros R, Albericio F, Kamiński ZJ
J Org Chem (76), 4506-4513 (2011)

Leishmania mexicana: LACK (Leishmania homologue of receptors for activated C-kinase) is a plasminogen binding protein.
Gómez-Arreaza A, Acosta H, Barros-Álvarez X, Concepcion JL, Albericio F, Avilan L.
Exp Parasitol (127), 752-761 (2011)

Biotin Ergopeptide Probes for Dopamine Receptors
Vendrell M, Molero A, Gonzalez S, Pérez-Capote K, Lluis C, McCormick PJ, Franco R, Cortés A, Casadó V, Albericio F, Royo M.
J Med Chem (54), 1080-1090 (2011)

Optimized Fmoc Solid-Phase Synthesis of the Cysteine-Rich Peptide Linaclotide.
Gongora M, Tulla-Puche J, Paradis M, Werbitzky O, Giraud M, Albericio F.
Biopolymers (96), 69-80 (2011)

Targeting nanosystems to human DCs via Fc receptor as an effective strategy to deliver antigen for immunotherapy.
Cruz LJ, Rueda F, Cordobilla B, Simon L, Hosta L, Albericio F, Domingo JC.
Mol Pharmacol (8), 104-116 (2011)

Structure, Synthesis, and Bioactivity of Natural Products with Hexahydropyrrolo[2,3-b]indole.
Ruiz P, Savina S, Albericio F, Álvarez M.
Chem-eur J (17), 1388-1408 (2011)

Study of various presentation forms for a peptide mimetic of Neisseria meningitidis serogroup capsular polysaccharide.
Garay H, Menéndez T, Cruz-Leal Y, Coizeau E, Noda J, Morera V, Guillén G, Albericio F, Reyes O.
Bioconjugate Chem (22), 33-41 (2011)

Solid-phase synthesis of a library of amphipatic hydantoins. Discovery of new hits for TRPV1 blockade
Gerona-Navarro G, González-Muñiz R, Fernández-Carvajal A, González-Ros JM, Ferrer-Montiel A, Carreño C, Albericio F and Royo M.
Acs Comb Sci, 5 (13), 458-65 (2011)

Affinity chromatography based on a combinatorial strategy for rerythropoietin purification
Martínez-Ceron MC, Marani MM, Taulés M, Etcheverrigaray M, Albericio F, Cascone O and Camperi SA.
Acs Comb Sci, 3 (13), 251-8 (2011)

Antioxidant, cytotoxic and apoptotic activity of Drosophyllum lusitanicum extracts
Sandra Gonçalves, Celine Xavier, Patrícia Costa, Fernando Alberício, and Anabela Romano
J Med Plants Res (4), 1601-1608 (2010)

One-Pot Access to Functionalized Chromenes and Quinolines via Domino Reactions of Salicylic Aldehydes and 4-Halo-2-Butynoates
Davide Bello, Javier Ruiz-Rodríguez, Fernando Albericio, and Rodolfo Lavilla
Eur J Org Chem, 5373-7379 (2010)

2,2,4,6,7-Pentamethyl-2,3-dihydrobenzofuran-5-methyl (Pbfm) as Alternative to Trityl Group for the Side-chain Protection of Cysteine and Asparagine/Glutamine
Oscar Garcia, Josep M. Bofill, Ernesto Nicolas, and Fernando Albericio
Eur J Org Chem, 3631-3640 (2010)

A Novel Family of Onium Salts Based Upon Isonitroso Meldrum's Acid Proves Useful as Peptide Coupling Reagents
Ayman El-Faham, Ramon Subirós-Funosas, and Fernando Albericio
Eur J Org Chem, 3641-3649 (2010)

Oxime Carbonates, Novel Reagents for the Introduction of Fmoc and Alloc protecting groups, free of Side-Reactions
Sherine N. Khattab, Ramon Subirós-Funosas, Ayman El-Faham, and Fernando Albericio
Eur J Org Chem, 3275-3280 (2010)

Solid-phase synthesis of aza Kahalalide F analogues. (2R,3R)-2-amino-3-azidobutanoic acid as precursor of the aza-threonine
Irene Izzo, Gerardo A. Acosta, Judit Tulla-Puche, Tommaso Cupido, Maria Jesus Martin-Lopez, Carmen Cuevas, and Fernando Albericio
Eur J Org Chem, 2536-2543 (2010)

Microwave assisted SPPS of amylin and its toxicity of the pure product to RIN-5F cells
Muthusamy K, Albericio F, Arvidsson PI, Govender P, Kruger HG, Maguire GE and Govender T.
Biopolymers, 3 (94), 323-30 (2010)

Capsosomes with Multilayered Subcompartments: Assembly and Loading with Hydrophobic Cargo
Leticia Hosta-Rigau, Brigitte Städler, Yan Yan, Edouard Nice, Joan K. Heath, Fernando Albericio and Frank Caruso
Adv Funct Mater (20), 59-66 (2010)

Synthesis and Aminolysis of N,N-Diethyl Carbamic Esters of HOBt derivatives
Sherine N. Khattab, Seham Y. Hassan, Ezzat A. Hamed, Fernando Albericio, Ayman. El- Faham
Korean J Chem Eng (31), 75-81 (2010)

Synthesis of 2-(4,6-dimethoxy-1,3,5-triazin-2-yloxyimino) derivatives: application in solution peptide synthesis
Al-Warhi TI, Al-Hazimi HM, El-Faham A and Albericio F.
Molecules, 12 (15), 9403-17 (2010)

Isolation, structural assignment, and total synthesis of barmumycin
Lorente A, Pla D, Cañedo LM, Albericio F and Alvarez M.
J Org Chem, 24 (75), 8508-15 (2010)

ChemMatrix(®) for complex peptides and combinatorial chemistry
García-Ramos Y, Paradís-Bas M, Tulla-Puche J and Albericio F.
J Pept Sci, 12 (16), 675-8 (2010)

Improving the brain delivery of gold nanoparticles by conjugation with an amphipathic peptide
Guerrero S, Araya E, Fiedler JL, Arias JI, Adura C, Albericio F, Giralt E, Arias JL, Fernández MS and Kogan MJ.
Nanomedicine-uk, 6 (5), 897-913 (2010)

The Antitumoral Depsipeptide IB-01212 Kills Leishmania through an Apoptosis-like Process Involving Intracellular Targets
Luque-Ortega JR, Cruz LJ, Albericio F and Rivas L.
Mol Pharm (7), 1608-1617 (2010)

Improved antimicrobial activity of h-lysozyme (107-115) by rational Ala substitution
González R, Albericio F, Cascone O and Iannucci NB.
J Pept Sci, 8 (16), 424-9 (2010)

PyOxP and PyOxB: the Oxyma-based novel family of phosphonium salts
Subirós-Funosas R, El-Faham A and Albericio F.
Org Biomol Chem, 16 (8), 3665-73 (2010)

Total regioselective control of tartaric acid
Spengler J, Fernández-Llamazares AI, Ruiz-Rodríguez J, Burger K and Albericio F.
J Org Chem, 16 (75), 5746-9 (2010)

Solid-phase synthesis of new Trp(Nps)-containing dipeptide derivatives as TRPV1 channel blockers
Pérez de Vega MJ, García-López MT, Zaccaro L, Royo M, Albericio F, Fernández-Carvajal A, Ferrer-Montiel A and González-Muñiz R.
Molecules, 7 (15), 4924-33 (2010)

Multifunctionalized gold nanoparticles with peptides targeted to gastrin-releasing peptide receptor of a tumor cell line
Hosta-Rigau L, Olmedo I, Arbiol J, Cruz LJ, Kogan MJ and Albericio F.
Bioconjugate Chem, 6 (21), 1070-8 (2010)

Targeted PLGA nano- but not microparticles specifically deliver antigen to human dendritic cells via DC-SIGN in vitro
Cruz LJ, Tacken PJ, Fokkink R, Joosten B, Stuart MC, Albericio F, Torensma R and Figdor CG.
J Control Release, 2 (144), 118-26 (2010)

Synthesis of orthogonally protected L-threo-beta-ethoxyasparagine
Spengler J, Pelay M, Tulla-Puche J and Albericio F.
Amino Acids, 1 (39), 161-5 (2010)

Sample preparation for sequencing hits from one-bead-one-peptide combinatorial libraries by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
Martínez-Ceron MC, Giudicessi SL, Marani MM, Albericio F, Cascone O, Erra-Balsells R and Camperi SA.
Anal Biochem, 2 (400), 295-7 (2010)

Amide-to-ester substitution allows fine-tuning of the cyclopeptide conformational ensemble
Cupido T, Spengler J, Ruiz-Rodriguez J, Adan J, Mitjans F, Piulats J and Albericio F.
Angew Chem Int Edit, 15 (49), 2732-7 (2010)

Engineering advanced capsosomes: maximizing the number of subcompartments, cargo retention, and temperature-triggered reaction
Chandrawati R, Hosta-Rigau L, Vanderstraaten D, Lokuliyana SA, Städler B, Albericio F and Caruso F.
Acs Nano, 3 (4), 1351-61 (2010)

A hybrid indoloquinolizidine peptide as allosteric modulator of dopamine D1 receptors
Soriano A, Vendrell M, Gonzalez S, Mallol J, Albericio F, Royo M, Lluís C, Canela EI, Franco R, Cortés A and Casadó V.
J Pharmacol Exp Ther, 3 (332), 876-85 (2010)

A convenient microwave-enhanced solid-phase synthesis of short chain N-methyl-rich peptides
Rodríguez H, Suarez M and Albericio F.
J Pept Sci, 3 (16), 136-40 (2010)

A novel dipeptidomimetic containing a cyclic threonine
Sicherl F, Cupido T and Albericio F.
Chemistry, 8 (46), 1266-8 (2010)

Amphiphilic peptides and their cross-disciplinary role as building blocks for nanoscience
Cavalli S, Albericio F and Kros A.
Chem Soc Rev, 1 (39), 241-63 (2010)

Postsynthetic modification of peptides: chemoselective C-arylation of tryptophan residues
Ruiz-Rodríguez J, Albericio F and Lavilla R.
Chemistry, 4 (16), 1124-7 (2010)

COMU: a third generation of uronium-type coupling reagents
El-Faham A and Albericio F.
J Pept Sci, 1 (16), 6-9 (2010)

Microwave irradiation and COMU: a potent combination for solid-phase peptide synthesis
Subiros-Funosas R, Acosta GA, El-Faham A and Albericio F
Tetrahedron Lett, 50 (45), 6200-02 (2009)

Manufacturing peptides as active pharmaceutical ingredients
Zompra A, Galanis A, Werbitzky O and Albericio F
Future Med Chem, 1 (2), 361-77 (2009)

Siamese depsipeptides: constrained bicyclic architectures
Ruiz-Rodríguez J, Spengler J and Albericio F.
Angew Chem Int Edit, 45 (48), 8564-7 (2009)

The synthesis of 1,2,3,6,6a,7-hexahydro-7-methyl-5-imino-1H-pyrrolo[1,2-c]imidazolo[5,4-b]indole
Pla D, Mills K, Joule JA, Albericio F and Álvarez M.
Arkivoc, 6, 260-69 (2009)

Design and facile solid-phase synthesis of peptide-based LPS-inhibitors containing PEG-like functionalities
Mas-Moruno C, Cascales L, Mora P, Cruz LJ, Pérez-Payá E and Albericio F.
Biopolymers, 6 (92), 508-17 (2009)

Solid-phase synthesis of chiral bicyclic guanidinium oligomers
Martos V, Castreño P, Royo M, Albericio F and de Mendoza J.
J Comb Chem, 3 (11), 410-21 (2009)

Screening of one-bead-one-peptide combinatorial library using red fluorescent dyes. Presence of positive and false positive beads
Marani MM, Martínez Ceron MC, Giudicessi SL, de Oliveira E, Côté S, Erra-Balsells R, Albericio F, Cascone O and Camperi SA.
J Comb Chem, 1 (11), 146-50 (2009)

Optimized Fmoc solid-phase synthesis of Thymosin alpha1 by side-chain anchoring onto a PEG resin
García-Ramos Y, Giraud M, Tulla-Puche J and Albericio F.
Biopolymers, 6 (92), 565-72 (2009)

Enhanced microwave-assisted method for on-bead disulfide bond formation: synthesis of alpha-conotoxin MII
Galanis AS, Albericio F and Grøtli M.
Biopolymers, 1 (92), 23-34 (2009)

Synthesis and applications of N-Hydroxylamine derivatives as potential replacement for HOBt
El-Faham A and Albericio F.
Eur J Org Chem, 10, 1499-501 (2009)

Antioxidant and in vitro inhibition of tumor cell growth by leaf extracts from the carob three (Ceratonia siliqua)
Custodio L, Fernandes E, Escapa AL, López-Aviles S, Fajardo A, Aligué R, Albericio F and Romano A.
Pharm Biol, 8 (47), 721-28 (2009)

Kahalalide F, an antitumor depsipeptide in clinical trials, and its analogues as effective antileishmanial agents
Cruz LJ, Luque-Ortega JR, Rivas L and Albericio F.
Mol Pharmaceut, 3 (6), 813-24 (2009)

Oxathiocoraline: Lessons to be learnt in the synthesis of complex N methylated depsipeptides
Bayó-Puxan N, Tulla-Puche J and Albericio F.
Eur J Org Chem, 18, 2957-74 (2009)

Total synthesis and antiproliferative activity screening of (+/-)-aplicyanins A, B and E and related analogues
Sísa M, Pla D, Altuna M, Francesch A, Cuevas C, Albericio F, Alvarez M
J Med Chem, 52 (20), 6217-23 (2009)

Solid-phase peptide synthesis in water using microwave-assisted heating
Galanis AS, Albericio F and Grøtli M.
Org Lett, 20 (11), 4488-91 (2009)

Solid-phase peptide synthesis using acetonitrile as a solvent in combination with PEG-based resins
Acosta GA, del Fresno M, Paradis-Bas M, Rigau-DeLlobet M, Côté S, Royo M and Albericio F.
J Pept Sci, 10 (15), 629-33 (2009)

Indoloquinolizidine-peptide hybrids as multiple agonists for D1 and D2 dopamine receptors
Vendrell M, Soriano A, Casadó V, Díaz JL, Lavilla R, Canela EI, Lluís C, Franco R, Albericio F, Royo M
ChemMedChem, 4 (9), 1514-22 (2009)

Oxyma: an efficient additive for peptide synthesis to replace the benzotriazole-based HOBt and HOAt with a lower risk of explosion
Subirós-Funosas R, Prohens R, Barbas R, El-Faham A and Albericio F.
Chemistry, 37 (15), 9394-403 (2009)

Adenosine A2A receptor-antagonist/dopamine D2 receptor-agonist bivalent ligands as pharmacological tools to detect A2A-D2 receptor heteromers
Soriano A, Ventura R, Molero A, Hoen R, Casadó V, Cortés A, Fanelli F, Albericio F, Lluís C, Franco R and Royo M.
J Med Chem, 18 (52), 5590-602 (2009)

COMU: a safer and more effective replacement for benzotriazole-based uronium coupling reagents
El-Faham A, Subirós Funosas R, Prohens R and Albericio F.
Chemistry, 37 (15), 9404-16 (2009)

Optical tweezers study of topoisomerase inhibition
Pla D, Sischka A, Albericio F, Alvarez M, Fernàndez-Busquets X and Anselmetti D.
Small, 11 (5), 1269-72 (2009)

Lamellarin D bioconjugates II: Synthesis and cellular internalization of dendrimer and nuclear location signal derivatives
Pla D, Martí M, Farrera-Sinfreu J, Pulido D, Francesch A, Calvo P, Cuevas C, Royo M, Aligué R, Albericio F and Alvarez M.
Bioconjugate Chem, 6 (20), 1112-21 (2009)

Lamellarin D bioconjugates I: Synthesis and cellular internalization of PEG-derivatives
Pla D, Francesch A, Calvo P, Cuevas C, Aligué R, Albericio F and Alvarez M.
Bioconjugate Chem, 6 (20), 1100-11 (2009)

Amino acid-protecting groups
Isidro-Llobet A, Alvarez M and Albericio F.
Chem Rev, 6 (10), 2455-504 (2009)

1,2-Dimethylindole-3-sulfonyl (MIS) as protecting group for the side chain of arginine
Isidro A, Latassa D, Giraud M, Alvarez M and Albericio F.
Org Biomol Chem, 12 (7), 2565-9 (2009)

Structure-activity relationships of SSAO/VAP-1 arylalkylamine-based substrates
Yraola F, Zorzano A, Albericio F and Royo M.
Chemmedchem, 4 (4), 495-503 (2009)

Synthesis of the pyrrolo[2,3-c]carbazole core of the dictyodendrins
Ayats C, Soley R, Albericio F and Alvarez M.
Org Biomol Chem, 5 (7), 860-2 (2009)

NMe amide as a synthetic surrogate for the thioester moiety in thiocoraline
Tulla-Puche J, Marcucci E, Prats-Alfonso E, Bayó-Puxan N and Albericio F.
J Med Chem, 3 (52), 834-9 (2009)

Solution- and solid-phase synthesis and anti-HIV activity of maslinic acid derivatives containing amino acids and peptides
Parra A, Rivas F, Lopez PE, Garcia-Granados A, Martinez A, Albericio F, Marquez N and Muñoz E.
Bioorgan Med Chem, 3 (17), 1139-45 (2009)

Conjugation of Kahalalide F with gold nanoparticles to enhance in vitro antitumoral activity
Hosta L, Pla-Roca M, Arbiol J, López-Iglesias C, Samitier J, Cruz LJ, Kogan MJ and Albericio F.
Bioconjugate Chem, 1 (20), 138-46 (2009)

A 6H-Pyran-3-one scaffold derived from a C-Glycoside
de la Figuera N, Fiol S, Fernández JC, Forns P, Fernández-Forner D and Albericio F
Lett Org Chem, 5 (5), 374-78 (2008)

[{Cu(pzPh)(Opo)}2(?-Cl)2]: A new dinuclear copper(II) complex with a chloride bridge and mixed blocking ligands
Yraola F, Albericio F, Corbella M and Royo M
Inorg Chim Acta, 8 (361), 2455-61 (2008)

Crystal structure of hexakis(4-fluorophenylethylammonium)decavanadate(V) tetrahydrate, (C8H11FN)6[V10O28] · 4H2O
Yraola F, Albericio F, Royo M and Solans X
Kristallogr (223), 45-47 (2008)

Solid phase preparation of 1,3-disubstituted indazole derivatives
de la Figuera N, Fiol S, Fernández JC, Forns P, Eastwood P and Albericio F
QSAR & Comb Sci, 39426 (27), 1267-73 (2008)

Stereomeric studies on the oxidation and alkylation of 4-thiazolidinones
Colombo A, Fernández JC, Fernández-Forner D, de la Figuera N, Albericio F and Forns P
Tetrahedron Lett, 10 (49), 1569-72 (2008)

Phenyl-EDOTn derivatives as super acid labile carboxylic acid protecting groups for peptide synthesis
Isidro-Llobet A, Álvarez M and Albericio F
Tetrahedron Lett, 20 (49), 3304-07 (2008)

Synthesis of natural product derivatives containing 2,4-concatenated oxazoles
Hernandez D, Riego E, Albericio F and Álvarez M
Eur J Org Chem (19), 3389-96 (2008)

Solid-phase combinatorial synthesis of a lysyl-tRNA synthetase (LysRS) inhibitory library
Farrera-Sinfreu J, Español Y, Geslain R, Guitart T, Albericio F, Ribas de Pouplana L and Royo M
J Comb Chem, 3 (10), 391-00 (2008)

Cysteine-S-trityl a key derivative to prepare N-methyl cysteines
Marcucci E, Bayó-Puxan N, Tulla-Puche J, Spengler J and Albericio F
J Comb Chem, 1 (10), 69-78 (2008)

Asymmetric synthesis of _-unsubstituted _-hydroxy acids
Spengler J and Albericio F
Curr Org Chem, 2 (5), 151-61 (2008)

Protection by conformationally restricted mobility: first solid-phase synthesis of triostin A
Tulla-Puche J, Marcucci E, Fermin M, Bayó-Puxan N and Albericio F
Chemistry, 15 (14), 4475-78 (2008)

Solid supports for the synthesis of peptides. From first used resin to the most sophisticated in the market
García-Martin F and Albericio F
Chem Today, 4 (26), 29-34 (2008)

PyClocK, the phosphonium salt derived from 6-Cl-HOBt
Subiros-Funosas R, Moreno JA, Bayó-Puxan N, Abu-Rabeah K, Ewenson A and Albericio F
Chem Today, 4 (26), 39425 (2008)

EDOTn and MIM, new peptide backbone protecting groups
Isidro-Llobet A, Just-Baringo X, Alvarez M and Albericio F
Biopolymers, 3 (90), 444-49 (2008)

Nanostructure formation enhances the activity of LPS-neutralizing peptides
Mas-Moruno C, Cascales L, Cruz LJ, Mora P, Pérez-Payá E and Albericio F
ChemMedChem, 11 (3), 1748-55 (2008)

Recent advances in lamellarin alkaloids: isolation, synthesis and activity
Pla D, Albericio F and Alvarez M
Anticancer Agents Med Chem, 7 (8), 746-60 (2008)

N,N,N',N'-tetramethylchloroformamidinium hexafluorophosphate (TCFH), a powerful coupling reagent for bioconjugation
Tulla-Puche J, Torres A, Calvo P, Royo M and Albericio F
Bioconjug Chem, 10 (19), 1968-71 (2008)

Tiratricol neutralizes bacterial endotoxins and reduces lipopolysaccharide-induced TNF-alpha production in the cell
Cascales L, Mas-Moruno C, Tamborero S, Aceña JL, Sanz-Cervera JF, Fustero S, Cruz LJ, Mora P, Albericio F and Pérez-Payá E
Chem Biol Drug Des, 4 (72), 320-28 (2008)

Synthesis and antitumor activity of mechercharmycin A analogues
Hernández D, Altuna M, Cuevas C, Aligué R, Albericio F and Alvarez M
J Med Chem, 18 (51), 5722-30 (2008)

THAL, a sterically unhindered linker for the solid-phase synthesis of acid-sensitive protected peptide acids
Isidro-Llobet A, Boas U, Jensen KJ, Alvarez M and Albericio F
J Org Chem, 18 (73), 7342-44 (2008)

Structure-activity relationship of kahalalide F synthetic analogues
Jiménez JC, López-Macià A, Gracia C, Varón S, Carrascal M, Caba JM, Royo M, Francesch AM, Cuevas C, Giralt E and Albericio F
J Med Chem, 16 (51), 4920-31 (2008)

Use of N-methylpiperazine for the preparation of piperazine-based unsymmetrical bis-ureas as anti-HIV agents
El-Faham A, Armand-Ugón M, Esté JA and Albericio F
ChemMedChem, 7 (3), 1034-37 (2008)

Conformationally restricted hydantoin-based peptidomimetics as inhibitors of caspase-3 with basic groups allowed at the S3 enzyme subsite
Vázquez J, García-Jareño A, Mondragón L, Rubio-Martinez J, Pérez-Payá E and Albericio F
ChemMedChem, 6 (3), 979-85 (2008)

Design and synthesis of FAJANU: a de novo C(2) symmetric cyclopeptide family
Garcia-Martin F, Cruz LJ, Rodriguez-Mias RA, Giralt E and Albericio F
J Med Chem, 11 (51), 3194-02 (2008)

Solid-phase synthesis of oligomers carrying several chromophore units linked by phosphodiester backbones
Aviñó A, Navarro I, Farrera-Sinfreu J, Royo M, Aymamí J, Delgado A, Llebaria A, Albericio F and Eritja R
Bioorg Med Chem Lett, 7 (18), 2306-10 (2008)

Design, synthesis and antiproliferative properties of oligomers with chromophore units linked by amide backbones
Farrera-Sinfreu J, Aviñó A, Navarro I, Aymamí J, Beteta NG, Varón S, Pérez-Tomás R, Castillo-Avila W, Eritja R, Albericio F and Royo M
Bioorg Med Chem Lett, 7 (18), 2440-44 (2008)

Morpholine-based immonium and halogenoamidinium salts as coupling reagents in Peptide synthesis1
El-Faham A and Albericio F
J Org Chem, 7 (73), 2731-37 (2008)

A novel protecting/activating strategy for beta-hydroxy acids and its use in convergent peptide synthesis
Spengler J, Ruíz-Rodríguez J, Yraola F, Royo M, Winter M, Burger K and Albericio F
J Org Chem, 6 (73), 2311-14 (2008)

Synthesis of oligonucleotide derivatives using ChemMatrix supports
Mazzini S, García-Martin F, Alvira M, Aviñó A, Manning B, Albericio F and Eritja R
Chem Biodivers, 1 (5), 209-18 (2008)

Advances in solid-phase cycloadditions for heterocyclic synthesis
Feliu L, Vera-Luque P, Albericio F and Álvarez M
J Comb Chem (9), 521-65 (2007)

Chlorotrityl chloride (CTC) resin as a convenient reusable protecting group
García-Martín F, Bayó-Puxan N, Cruz LJ, Bohling JC and Albericio F
QSAR & Comb Sci (26), 1027-35 (2007)

Regioselective Monobromination of Free and Protected Phenols
Pla D, Albericio F and Álvarez M
Eur J Org Chem (12), 1921-24 (2007)

Synthesis of a 24-Membered Cyclic Peptide-Biphenyl Hybrid
Montero A, Albericio F, Royo M and Herradón B
Eur J Org Chem (8), 1301-08 (2007)

Preparation of penta-azole containing cyclopeptides: challenges in macrocyclization
Hernandez D, Riego E, Francesch A, Cuevas C, Albericio F and Alvarez M
Tetrahedron (63), 9862-70 (2007)

Formation of dihydrouracils via cyclization of N-substituted 3-thioureidopropanoic acids and facile desulfurization
Delpiccolo Carina ML, Albericio F, Schiksnis RA and Michelotti EL
Tetrahedron (63), 8949-53 (2007)

From one-bead-one-compound concept to one-bead-one-reactor
Marani MM, Paradís M, Tulla-Puche J, Côte S, Camperi S, Cascone O and Albericio F
J Comb Chem (9), 395-98 (2007)

Solid-phase synthesis of sulfamate peptidomimetics
Farrera-Sinfreu J, Albericio F and Royo M
J Comb Chem (9), 501-06 (2007)

Amide-to-ester substitution in coiled coils: the effect of removing hydrogen bonds on protein structure
Scheike JA, Baldauf C, Spengler J, Albericio F, Pisabarro MT and Koksch B
Angew Chem Int Edit (46), 7766-69 (2007)

Novel synthesis of bisaryl acetylenes
Soley R, Albericio F and Álvarez M
Synthesis (10), 1559-65 (2007)

Does the solid-phase synthesis of a tetrapeptide represent a challenge at the onset of the XXI century? The case of cyclo(3R)-3-hydroxydecanoyl-L-seryl-(3R)-3-hydroxydecanoyl-L-seryl
Teixidó M, Caba JM, Prades R, Zurita E, Martinell M, Vilaseca M, Albericio F & Giralt E
Int J Pept Res Ther (13), 313-27 (2007)

Chemical synthesis of 19F-labeled HIV-1 protease using Fmoc-chemistry and ChemMatrix resin
Frutos S, Tulla-Puche J, Albericio F and Giralt E
Int J Pept Res Ther (13), 221-27 (2007)

Beyond azathiocoraline: Synthesis of analogues
Bayó-Puxan N, Fernández A, Tulla-Puche J, Riego E, Álvarez M and Albericio F
Int J Peptides Res Therapeutics (13), 295-06 (2007)

New developments in the synthesis of oligonucleotide-peptide conjugates
Portela C, Mascareñas JL, Albericio F, Mazzini S, Caminal C, Ramos R, Ocampo SM and Eritja R
Nucleos Nucleot Nucl, 8-9 (26), 963-67 (2007)

Partially fluorinated heterocycles from 4,4-Bis(trifluoromethyl)-hetero-1,3-dienes via C-F bond activation
Burger K, Helmreich B, Henning L, Spengler J, Albericio F and Fuchs A
Monatsh Chem (138), 227-36 (2007)

A simple machine-assisted protocol for solid-phase synthesis of depsipeptides
Spengler J, Koksch B and Albericio F
Biopolymers (88), 823-28 (2007)

Fmoc-2-mercaptobenzothiazole for the introduction of the Fmoc moiety free of side-reactions
Isidro-Llobet A, Just-Baringo X, Ewenson A, Álvarez M and Albericio F
Biopolymers (88), 733-37 (2007)

The synthesis of naturally occurring peptides and their analogs
Cupido T, Tulla-Puche J, Spengler J and Albericio F
Curr Opin Drug Discover Develop (10), 768-83 (2007)

Enolase as a plasminogen binding protein in Leishmania Mexicana
Vanegas G, Quiñones W, Carrasco-López C, Concepción JL, Albericio F and Avilán L
Parasitology Res (101), 1511-16 (2007)

Design and synthesis of indole-based peptoids as potent noncompetitive antagonists of transient receptor potential vanilloid 1
Quintanar-Audelo M, Fernández-Carvajal A, Van Den Nest W, Carreño C, Ferrer-Montiel A & Albericio F
J Med Chem (50), 6133-43 (2007)

Identification of protein-binding peptides by direct MALDI-TOF-MS analysis of peptide beads selected from the screening of one-bead-one peptide combinatorial libraries
Marani MM, Oliveira E, Côte S, Camperi SA, Albericio F and Cascone O
Anal Biochem (370), 215-22 (2007)

Novel proton acceptor immonium-type coupling reagents: Application in solution and solid phase peptide synthesis
El-Faham A and Albericio F
Org Lett (9), 4475-77 (2007)

A nonacid degradable linker for solid-phase synthesis
Colombo A, de la Figuera N, Fernàndez JC, Fernández-Forner D, Albericio F and Forns P
Org Lett (9), 4319-22 (2007)

Ds-oligonucleotide-peptide conjugates featuring peptides from the leucine zipper region of fos as switchable receptors for the oncoprotein Jun
Portela C, Albericio F, Eritja R, Castedo L and Mascareñas JL
Chembiochem, 10 (8), 1110-14 (2007)

Synthesis and structure-activity relationship of cytotoxic marine cyclodepsipeptide IB-01212 analogs
Cruz LJ, Francesch A, Cuevas C and Albericio F
ChemMedChem (2), 1076-84 (2007)

Peptides and metallic nanoparticles for biomedical applications
Kogan MJ, Olmedo I, Hosta L, Guerrero AR, Cruz LJ and Albericio F
Nanomedicine-uk (2), 287-06 (2007)

Novel ergopeptides as dual ligands for adenosine and dopamine receptors
Vendrell M, Angulo E, Casado V, Lluis C, Franco R, Albericio F and Royo M
J Med Chem (50), 3062-69 (2007)

Understanding the mechanism of action of the novel SSAO substrate (C7NH10)6(V10O28).2H2O, a prodrug of peroxovanadate insulin mimetics
Yraola F, García-Vicente S, Marti L, Albericio F, Zorzano A and Royo M
Chem Biol Drug Des, 6 (69), 423-28 (2007)

Smallest peptoids with antiproliferative activity on human neoplastic cells
Mas-Moruno C, Cruz LJ, Mora P, Messeguer A, Pérez-Payá E and Albericio F
J Med Chem (50), 2443-49 (2007)

Solid-phase synthesis of oxathiocoraline by a key intermolecular disulfide dimer
Tulla-Puche J, Bayó-Puxan N, Moreno JA, Francesch AM, Cuevas C, Álvarez M and Albericio F
J Am Chem Soc (129), 5322-23 (2007)

p-Nitromandelic acid as highly acid stable safety-catch linker for solid phase synthesis of peptide and depsipeptide acids
Isidro-Llobet A, Álvarez M, Burger K, Spengler J and Albericio F
Org Lett (9), 1429-32 (2007)

Synthesis of IB-01211. A cyclic peptide containing 2,4-concatenated thia- and oxazoles
Hernandez D, Riego E, Vilar G, Francesch A, Cuevas C, Albericio F and Álvarez M
Org Lett (9), 809-11 (2007)

Inhibition of VAP1: Quickly gaining ground as an anti-inflammatory therapy
Yraola F, Albericio F and Royo M
Chem Med Chem (2), 173-74 (2007)

Oral insulin-mimetic compounds that act independently of insulin
García-Vicente S, Yraola F, Marti L, González-Muñoz E, García-Barrado MJ, Cantó C, Abella A, Bour S, Artuch R, Sierra C, Brandi N, Carpéné C, Moratinos J, Camps M, Palacín M, Testar X, Gumà A, Albericio F, Royo M, Mian A and Zorzano A
Diabetes, 2 (56), 486-93 (2007)

1-Hydroxy- 6,7-Dimethoxy- -8-nitro-1,2,3,4-tetrahydroisoquinoline
Roqué N, Cironi P, Solans X, Albericio F and Álvarez M
Acta Cryst (E62), o2285-87 (2006)

Solid-phase synthesis and structural study of substituted 1,4,5,6-tetrahydro-6-oxopyridine-3-carboxylic acids
Rodríguez H, Martín O, Ochoa E, Suárez M, Reyes O, Garay H, Albericio F, Seoane C and Martín N
QSAR & Comb Sci (25), 921-27 (2006)

Solid-phase N-electrophilic amination of 2-aminopyridines: preparation of 2-substituted-[1,2,4]triazolo[1,5-a]pyridine derivatives
Fernández JC, Solé L, Fernández D, Figuera N, Forns P and Albericio F
QSAR & Comb Sci (25), 961-65 (2006)

Synthesis of _-unsubstituted _-hydroxy and (E)-_,_-unsaturated carboxylic acid amides from _-amino acids: a new direction for the Arndt-Eistert reaction
Spengler J, Ruiz J, Burger K and Albericio F
Tetrahedron Lett (47), 4557-60 (2006)

Microwave-assisted synthesis of 1,3-dihydro-[1,2,5]thiadiazolo[3,4-b]pyrazine-2,2-dioxides
Sevilla S, Forns P, Figuera N, Fernández JC, Eastwood P and Albericio F
Tetrahedron Lett (47), 8603-06 (2006)

Design and synthesis of new immonium type coupling reagents
El-Faham A, Khattab S, Abdul-Ghani M and Albericio F
Eur J Org Chem (6), 1563-73 (2006)

A convenient semicarbazide resin for the solid-phase synthesis of peptide ketones and aldehydes
Vázquez J and Albericio F
Tetrahedron Lett (47), 1657-61 (2006)

Facile solid-phase synthesis of biotinylated alkyl thiols
Prats E, Garcia F, Bayo N, Cruz LJ, Pla M, Samitier J, Errachid A and Albericio F
Tetrahedron (62), 6876-81 (2006)

Role of the acid group in the pictet spengler reaction of ±-amino acids
Figuera N, Fiol S, Forns P, Fernàndez JC, Fernández D and Albericio F
Synlett (12), 1903-07 (2006)

ChemMatrix®, a polyethylene glycol (PEG)-based support for the solid-phase synthesis of complex peptides
García F, Quintanar M, García Y, Cruz LJ, Gravel C, Furic R, Côté S, Tulla J and Albericio F
J Comb Chem (8), 213-20 (2006)

Solid-phase syntheses of azathiocoralines
Bayó N, Fernández A, Riego E, Tulla J, Cuevas C, Álvarez M and Albericio F
Chem Eur J (12), 9001-09 (2006)

Synthetic approaches for disulfide-free circular Bovine Pancreatic Trypsin Inhibitor (c-BPTI) analogues
Tulla J, Getun IV, Angell Y, Alsina J, Albericio F, Woodward C and Barany G
Int J Pept Res Ther (12), 93-04 (2006)

Hexafluoroacetone as protecting and activating reagent: New routes to amino, hydroxy and mercapto acids and their application for peptide, glyco- and depsipeptide modification
Burger K, Böttcher C, Spengler J and Albericio F
Chem Rev (106), 4728-46 (2006)

New efficient substrates for semicarbazide-sensitive amine oxidase/VAP-1 enzyme: analysis by SARs and computational docking
Yraola F, García-Vicente S, Fernández-Recio J, Albericio F, Zorzano A, Marti L and Royo M
J Med Chem, 21 (49), 6197-08 (2006)

Convergent approaches for the synthesis of the antitumoral peptide, Kahalalide F. Study of orthogonal protecting groups
Gracia C, Isidro A, Cruz LJ, Acosta GA, Alvarez M, Cuevas C, Giralt E and Albericio F
J Org Chem (71), 7196-04 (2006)

Design of a minimized cyclic tetrapeptide that neutralizes bacterial endotoxins
Mora P, Mas C, Tamborero S, Cruz LJ, Pérez-Payá E and Albericio F
J Pept Sci, 7 (12), 491-96 (2006)

Synthesis of alpha-trifluoromethyl alpha-amino acids with aromatic, heteroaromatic and ferrocenyl subunits in the side chain
Burger K, Henning L, Tsouker P, Spengler J, Albericio F and Koksch B
Amino Acids (31), 55-62 (2006)

Synthesis and structure-activity relationship study of potent cytotoxic analogues of the marine alkaloid Lamellarin D
Pla D, Marchal A, Olsen C, Francesca A, Cuevas C, Albericio F and Álvarez M
J Med Chem (49), 3257-68 (2006)

Total solid-phase synthesis of the marine cyclodepsipeptide IB-01212
Cruz LJ, Cuevas C, Cañedo L, Giralt E and Albericio F
J Org Chem (71), 3339-44 (2006)

IB-01212, a new cytotoxic cyclodepsipeptide isolated from the marine fungus Clonostachys sp
Cruz LJ, Martinez M, Perez J, Trujillo M, Rodriguez-Mias R, Oliveira E, Giralt E, Albericio F and Canedo LM
J Org Chem (71), 3335-38 (2006)

Solid-phase chemistry in the total synthesis of non-peptidic natural products
Cironi P, Álvarez M and Albericio F
Mini Rev Med Chem (6), 44500 (2006)

Cell-penetrating cis-gamma-amino-l-proline-derived peptides
Farrera-Sinfreu J, Giralt E, Castel S, Albericio F and Royo M
J Am Chem Soc, 127 (26), 9459-9468 (2005)

Multicomponent reactions with dihydroazines: efficient synthesis of a diverse set of pyrido-fused tetrahydroquinolines
Carranco I, Díaz JL, Jiménez O, Vendrell M, Albericio F, Royo M and Lavilla R
J Comb Chem, 7 (1), 33-41 (2005)

A straightforward synthesis of 5'-peptide oligonucleotide conjugates using N(alpha)-Fmoc-protected amino acids
Ocampo SM, Albericio F, Fernández I, Vilaseca M and Eritja R
Org Lett, 7 (20), 4349-4352 (2005)

A new strategy for solid-phase depsipeptide synthesis using recoverable building blocks
Albericio F, Burger K, Ruíz-Rodríguez J and Spengler J
Org Lett, 7 (4), 597-600 (2005)

Preparation of de novo globular proteins based on proline dendrimers
Sanclimens G, Crespo L, Giralt E, Albericio F and Royo M
J Org Chem, 70 (16), 6274-6281 (2005)

Peptide and amide bond-containing dendrimers
Crespo L, Sanclimens G, Pons M, Giralt E, Royo M and Albericio F
Chem Rev, 105 (5), 1663-1681 (2005)

Solid-phase combinatorial synthesis of peptide-biphenyl hybrids as calpain inhibitors
Montero A, Albericio F, Royo M and Herradón B
Org Lett, 6 (22), 4089-4092 (2004)

Solid-phase synthesis of second-generation polyproline dendrimers
Sanclimens G, Crespo L, Giralt E, Royo M and Albericio F
Biopolymers, 76 (4), 283-297 (2004)

Solid-phase syntheses of furopyridine and furoquinoline systems
Cironi P, Tulla-Puche J, Barany G, Albericio F and Alvarez M
Org Lett, 6 (9), 1405-1408 (2004)

From production of peptides in milligram amounts for research to multi-tons quantities for drugs of the future
Bruckdorfer T, Marder O and Albericio F
Curr Pharm Biotechnol, 5 (1), 29-43 (2004)

Developments in peptide and amide synthesis
Albericio F
Curr Opin Chem Biol, 8 (3), 211-221 (2004)

A new class of foldamers based on cis-gamma-amino-L-proline
Farrera-Sinfreu J, Zaccaro L, Vidal D, Salvatella X, Giralt E, Pons M, Albericio F and Royo M
J Am Chem Soc, 126 (19), 6048-6057 (2004)

Synthesis and NMR structure of p41icf, a potent inhibitor of human cathepsin L
Chiva C, Barthe P, Codina A, Gairí M, Molina F, Granier C, Pugnière M, Inui T, Nishio H, Nishiuchi Y, Kimura T, Sakakibara S, Albericio F and Giralt E
J Am Chem Soc, 125 (6), 1508-1517 (2003)

Solid-phase synthesis of the cyclic lipononadepsipeptide [N-Mst(Ser1), d-Ser4, L-Thr6, L-Asp8, L-Thr9]syringotoxin
Bayó N, Jiménez JC, Rivas L, Nicolás E and Albericio F
Chemistry, 9 (5), 1096-1103 (2003)

Synthesis and SAR of alpha-acylaminoketone ligands for control of gene expression
Tice CM, Hormann RE, Thompson CS, Friz JL, Cavanaugh CK, Michelotti EL, Garcia J, Nicolas E and Albericio F
Bioorg Med Chem Lett, 13 (3), 475-478 (2003)

Qualitative colorimetric tests for solid phase synthesis
Vázquez J, Qushair G and Albericio F
Methods Enzymol, 369, 21-35 (2003)

Saturated resins or stress of the resin
Sanclimens G, Crespo L, Pons M, Giralt E, Albericio F and Royo M
Tetrahedron Letters, 44 (9), 1751-1754 (2003)

Tentoxin as a scaffold for drug discovery. Total solid-phase synthesis of tentoxin and a library of analogues
Jiménez JC, Chavarría B, López-Macià A, Royo M, Giralt E and Albericio F
Org Lett, 5 (12), 2115-2118 (2003)

Solid-phase total synthesis of the pentacyclic system lamellarins U and L
Cironi P, Manzanares I, Albericio F and Alvarez M
Org Lett, 5 (16), 2959-2962 (2003)

Bicyclic homodetic peptide libraries: comparison of synthetic strategies for their solid-phase synthesis
Teixido M, Altamura M, Quartara L, Giolitti A, Maggi CA, Giralt E and Albericio F
J Comb Chem, 5 (6), 760-768 (2003)