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Past Events

The DNA damage response in human disease

Travis Stracker (IRB Barcelona) and John H. J. Petrini, Memorial Sloan-Kettering Cancer Center (USA)
Barcelona, Spain. 28-30 May, 2012

The cellular DNA damage response (DDR) is activated following the detection of DNA lesions with the goal of protecting the integrity of genetic information. The DDR is a composite of cell cycle checkpoints, DNA repair, transcriptional programs, and in some cases apoptosis or senescence. Defects in the DDR, particularly the response to DNA double-strand breaks, underlie many human hereditary diseases that lead to severe pathological outcomes that include neurodegeneration, microcephaly, immodeficiency, anemia and increased predisposition to cancer. Understanding how defects in the DDR cause these various human pathologies remains an active area of investigation that will yield new insights in to the etiology of complex human diseases and inform treatment regimens.

This conference brings together experts in the DNA damage response to discuss recent advances in the field and their relationship to human disease. The number of participants will be limited to facilitate discussion of key issues and interactions between participants.



Registration deadline: May 6, 2012

There is no registration fee for this conference, but the number of participants is limited.

Participants are invited to submit abstracts, a number of which will be selected for short talk and poster presentations. Abstracts should include a title, authors, affiliations, summary (max 250 words) and references.

Trustees:
  • Generalitat de catalunya
  • Generalitat de catalunya. Salut
  • Universidad de Barcelona
  • Fundaci√≥n BBVA

Institute for Research in Biomedicine (IRB Barcelona)

Parc Científic de Barcelona Parc Científic de Barcelona

C/ Baldiri Reixac 10
08028 Barcelona - Spain
Tel: +34 93 402 02 50 | Fax: +34 93 403 71 14
infoarrobairbbarcelona.org