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Plataformas Científicas y Servicios

Plataformas Científicas y Servicios

Genómica funcional

Herbert Auer

Herbert Auer

Jefe de Genómica Funcional

Tel Oficina : +34 93 403 98 03

correo-e : herbert.auerirbbarcelona.org

Introducción

The IRB Barcelona Functional Genomics Core Facility (FGC) serves researchers from academia and industry. We provide comprehensive support to projects whenever genome-wide measurements of DNA and RNA, and the manipulation of gene expression are required.

Tools for Genomic Analysis

The facility provides tools for:

  • miRNAs
  • transcriptomics
  • DNA copy numbers
  • ChIP-Seq
  • genomic sequencing
  • SNPs

Genome-wide measurements of DNA alterations and gene expression on the RNA level can be a challenge during research projects. The facility provides a complete service to work with researchers throughout the entire project. In addition to cutting-edge tools such as microarrays from Affymetrix and NimbleGen and Next Generation Sequencing by Illumina, the facility provides a consultancy service regarding genomic analysis.

Alteration of Gene Expression

The FGC provides IRB Barcelona and IBMB (CSIC) researchers with the following clones:

  • human shRNAs
  • mouse shRNAs
  • human ORFs (for IRB Barcelona only)

Reverse genetics calls for efficient tools to alter gene expression. The FGC provides almost 200,000 clones for genetic manipulation. These include all of Sigma's TRC1 human and mouse shRNA clones for knock-down of expression, together with Open Biosystems human ORF clones for over-expression. ORF clones are also useful as probes for in situ hybridisation or Northern blots.

shRNA clones come in lentiviral vectors for efficient infection of many cell types, including non-dividing ones.

ORF clones contain the gateway system for hassle-free transfer into any kind of expression vector.

Más información

Búsqueda de publicaciones científicas

Búsqueda de publicaciones científicas


  • Generalitat de catalunya
  • Generalitat de catalunya. Salut
  • Universidad de Barcelona
  • Parc cientific

Instituto de Investigación Biomédica (IRB Barcelona)
Parque Científico de Barcelona
C/ Baldiri Reixac 10
08028 Barcelona - España
Tel: +34 93 402 02 50 | Fax: +34 93 403 71 14
infoarrobairbbarcelona.org