Oscar Reina

    <p>Oscar Reina</p>
    Research Group: 
    Biostatistics/ Bioinformatics
    Unit: 
    BIOINFORMATICS-BIOSTATISTICS UNIT
    Position: 
    Senior Research Officer
    Office: 
    EA01A06-BIS
    Telephone: 
    +34 93 40 20553
    Email: 
    oscar.reina@irbbarcelona.org

     

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    Selected group publications

    A genome editing approach to study cancer stem cells in human tumors
    Cortina C, Turon G, Stork D, Hernando-Momblona X, Sevillano M, Aguilera M, Tosi S, Merlos-Suárez A, Stephan-Otto Attolini C, Sancho E and Batlle E.
    EMBO Mol Med, (2017)
    Mex3a Marks a Slowly Dividing Subpopulation of Lgr5+ Intestinal Stem Cells
    Barriga FM, Montagni E, Mana M, Mendez-Lago M, Hernando-Momblona X, Sevillano M, Guillaumet-Adkins A, Rodriguez-Esteban G, Buczacki SJA, Gut M, Heyn H, Winton DJ, Yilmaz OH, Attolini CS, Gut I and Batlle E.
    Cell Stem Cell, 20 (6), 801-816.e7 (2017)
    Targeting metastasis-initiating cells through the fatty acid receptor CD36
    Pascual G, Avgustinova A, Mejetta S, Martín M, Castellanos A, Attolini CS, Berenguer A, Prats N, Toll A, Hueto JA, Bescós C, Di Croce L and Benitah SA.
    Nature, 541 (7635), 41-45 (2017)
    Designing alternative splicing RNA-seq studies. Beyond generic guidelines
    Stephan-Otto Attolini C, Peña V and Rossell D.
    Bioinformatics, 31 (22), 3631-7 (2015)
    Inosine modifications in human tRNAs are incorporated at the precursor tRNA level
    Torres AG, Piñeyro D, Rodríguez-Escribà M, Camacho N, Reina O, Saint-Léger A, Filonava L, Batlle E and Ribas de Pouplana L.
    Nucleic Acids Res, 43 (10), 5145-57 (2015)
    dDsk2 regulates H2Bub1 and RNA polymerase II pausing at dHP1c complex target genes
    Kessler R, Tisserand J, Font-Burgada J, Reina O, Coch L, Attolini CS, Garcia-Bassets I and Azorín F.
    Nat Commun, 6 7049 (2015)
    Stromal gene expression defines poor-prognosis subtypes in colorectal cancer
    Calon A, Lonardo E, Berenguer-Llergo A, Espinet E, Hernando-Momblona X, Iglesias M, Sevillano M, Palomo-Ponce S, Tauriello DV, Byrom D, Cortina C, Morral C, Barceló C, Tosi S, Riera A, Attolini CS, Rossell D, Sancho E and Batlle E.
    Nat Genet, 47 (4), 320-329 (2015)
    The transcription factor GATA6 enables self-renewal of colon adenoma stem cells by repressing BMP gene expression
    Whissell G, Montagni E, Martinelli P, Hernando-Momblona X, Sevillano M, Jung P, Cortina C, Calon A, Abuli A, Castells A, Castellvi-Bel S, Nacht AS, Sancho E, Stephan-Otto Attolini C, Vicent GP, Real FX and Batlle E.
    Nat Cell Biol, 16 (7), 695-707 (2014)
    Ibf1 and Ibf2 are novel CP190-interacting proteins required for insulator function
    Cuartero S, Fresán U, Reina O, Planet E and Espinàs ML.
    Embo J, 33 (6), 637-47 (2014)
    chroGPS, a global chromatin positioning system for the functional analysis and visualization of the epigenome
    Font-Burgada J, Reina O, Rossell D and Azorín F.
    Nucleic Acids Res, 42 (4), 2126-37 (2014)
    Sequential stopping for high-throughput experiments
    Rossell D and Müller P.
    Biostatistics, 14 (1), 75-86 (2013)
    Bayesian Model Selection in High-Dimensional Settings
    Johnson, V.E. and Rossell, D.
    J Am Stat Assoc, 107 (498), 649-660 (2012)
    htSeqTools: high-throughput sequencing quality control, processing and visualization in R
    Planet E, Attolini CS, Reina O, Flores O and Rossell D.
    Bioinformatics, 28 (4), 589-90 (2012)
    The intestinal stem cell signature identifies colorectal cancer stem cells and predicts disease relapse
    Merlos-Suárez A, Barriga FM, Jung P, Iglesias M, Céspedes MV, Rossell D, Sevillano M, Hernando-Momblona X, da Silva-Diz V, Muñoz P, Clevers H, Sancho E, Mangues R and Batlle E.
    Cell Stem Cell, 8 (5), 511-24 (2011)
    On the use of non-local prior densities in Bayesian hypothesis tests
    Johnson VE and Rossell D.
    J R Stat Soc B, 72 (2), 143-170 (2010)
    Ectopic expression of germline genes drives malignant brain tumor growth in Drosophila
    Janic A, Mendizabal L, Llamazares S, Rossell D and Gonzalez C.
    Science, 330 (6012), 1824-7 (2010)
    GaGa: a parsimonious and flexible model for differential expression analysis
    Rossell D.
    Ann Appl Stat, 3 (3), 1035-51 (2009)
    Drosophila HP1c isoform interacts with the zinc-finger proteins WOC and Relative-of-WOC to regulate gene expression
    Font-Burgada J, Rossell D, Auer H and Azorín F.
    Gene Dev, 22 (21), 3007-23 (2008)
    Full publication list