Roeland Boer

Research Group:

Structural Biology of Protein & Nucleic Acid Complexes and Molecular Machines

Unit:

STRUCTURAL & COMPUTATIONAL BIOLOGY

Position:

Alumni - Postdoctoral Fellow

Office:

EMPBB43

Telephone:

+34 93 40 34953

Email:

roeland.boer@irbbarcelona.org

Left IRB Barcelona in June 2014

Selected group publications

Structure-Driven Discovery of α,γ-Diketoacid Inhibitors Against UL89 Herpesvirus Terminase

Bongarzone S., Nadal M., Kaczmarska Z., Machón C., Álvarez M., Albericio F., Coll M.

ACS Omega, 3 (8), 8497-8505 (2018)

Structural basis of a histidine-DNA nicking/joining mechanism for gene transfer and promiscuous spread of antibiotic resistance

Pluta R, Boer DR, Lorenzo-Díaz F, Russi S, Gómez H, Fernández-López C, Pérez-Luque R, Orozco M, Espinosa M and Coll M.

P Natl Acad Sci Usa, 114 (32), E6526-E653 (2017)

Conformational plasticity of RepB, the replication initiator protein of promiscuous streptococcal plasmid pMV158

Boer DR, Ruiz-Masó JA, Rueda M, Petoukhov MV, Machón C, Svergun DI, Orozco M, del Solar G and Coll M.

Sci Rep, 6 20915 (2016)

Structural basis for DNA binding specificity by the auxin-dependent ARF transcription factors

Boer DR, Freire-Rios A, van den Berg WA, Saaki T, Manfield IW, Kepinski S, López-Vidrieo I, Franco-Zorrilla JM, de Vries SC, Solano R, Weijers D and Coll M.

Cell, 156 (3), 577-89 (2014)

Thread insertion of a bis(dipyridophenazine) diruthenium complex into the DNA double helix by the extrusion of AT base pairs and cross-linking of DNA duplexes

Boer DR, Wu L, Lincoln P and Coll M.

Angew Chem Int Edit, 53 (7), 1949-52 (2014)

Human mitochondrial transcription factor A induces a U-turn structure in the light strand promoter

Rubio-Cosials A, Sidow JF, Jiménez-Menéndez N, Fernández-Millán P, Montoya J, Jacobs HT, Coll M, Bernadó P and Solà M.

Nat Struct Mol Biol, 18 (11), 1281-9 (2011)

The structure of a transcription activation subcomplex reveals how σ(70) is recruited to PhoB promoters

Blanco AG, Canals A, Bernués J, Solà M and Coll M.

Embo J, 30 3776-3785 (2011)

Structure and inhibition of herpesvirus DNA packaging terminase nuclease domain

Nadal M, Mas PJ, Blanco AG, Arnan C, Solà M, Hart DJ and Coll M.

P Natl Acad Sci Usa, 107 (37), 16078-83 (2010)

Human mitochondrial mTERF wraps around DNA through a left-handed superhelical tandem repeat

Jiménez-Menéndez N, Fernández-Millán P, Rubio-Cosials A, Arnan C, Montoya J, Jacobs HT, Bernadó P, Coll M, Usón I and Solà M.

Nat Struct Mol Biol, 17 (7), 891-3 (2010)

Plasmid replication initiator RepB forms a hexamer reminiscent of ring helicases and has mobile nuclease domains

Boer DR, Ruíz-Masó JA, López-Blanco JR, Blanco AG, Vives-Llàcer M, Chacón P, Usón I, Gomis-Rüth FX, Espinosa M, Llorca O, del Solar G and Coll M.

Embo J, 28 (11), 1666-78 (2009)

Molecular recognition of a three-way DNA junction by a metallosupramolecular helicate

Oleksy A, Blanco AG, Boer R, Usón I, Aymamí J, Rodger A, Hannon MJ and Coll M.

Angew Chem Int Edit, 45 (8), 1227-31 (2006)

The structure of phage φ29 transcription regulator p4-DNA complex reveals an N-hook motif for DNA binding

Badia D, Camacho A, Pérez-Lago L, Escandón C, Salas M and Coll M

Mol Cell, 22 73-81 (2006)

Recognition and processing of the origin of transfer DNA by conjugative relaxase TrwC

Guasch A, Lucas M, Moncalián G, Cabezas M, Pérez-Luque R, Gomis-Rüth FX, de la Cruz F and Coll M.

Nat Struct Mol Biol, 10 (12), 1002-10 (2003)

The bacterial conjugation protein TrwB resembles ring helicases and F1-ATPase

Gomis-Rüth FX, Moncalián G, Pérez-Luque R, González A, Cabezón E, de la Cruz F and Coll M.

Nature, 409 (6820), 637-41 (2001)

Crystal structure of a DNA Holliday junction

Ortiz-Lombardía M, González A, Eritja R, Aymamí J, Azorín F and Coll M.

Nat Struct Mol Biol, 6 (10), 913-7 (1999)