Barcelona BioMed Seminars

Modeling human diseases in C. elegans: Could CRISPR and worms help to improve your health?

22 Feb 2017

Speaker:  Julián Cerón Madrigal, PhD - Bellvitge Biomedical Research Institute, IDIBELL 

 

Organizer: IRB Barcelona
Date: Wednesday, 22nd of February 2017, 15.00h
Place: Aula Fèlix Serratosa, Parc Científic de Barcelona, Spain

Host: Marco Milán - IRB Barcelona

Abstract:

Our group is interested in modeling human diseases in C. elegans to understand fundamental questions in pathologies driven by genetic alterations. Regarding cancer, we are studying the mechanisms of resistance to chemotherapeutic agents and the oncogenic effect of mutations in splicing-related genes. In a different project, we have established a C. elegans model for a subtype of Retinitis Pigmentosa (Rubio-Peña et al, 2015) that is providing new insights on how mutations in ubiquitous spliceosomal proteins can produce a tissue-specific disease.

Cell and Developmental Biology Programme Seminar