News

Institutional news
<p>Joan J Guinovart, IRB Barcelona director</p>
5 Oct 2011

The Severo Ochoa Award involves the allocation of four million euros to each of the eight institutes honoured with this distinction

Institutional news
<p>Roger Gomis (c) IRB Barcelona</p>
3 Oct 2011

Promoted by the scientist Roger Gomis, Supragen is the third spin-off at IRB Barcelona, the second founded this year

Institutional news
<p>Ernest Giralt (c) IRB Barcelona</p>
30 Sep 2011

Spain’s Ministry of Sciences gives the award in recognition of his
contributions to the design, synthesis, controlled modification and
structure of peptides and proteins.

Institutional news
<p>Joan Massagué (c) IRB Barcelona</p>
29 Sep 2011

The award is given by the AECC in recognition of Massagué’s
contributions to understanding cancer metastasis

Institutional news
<p>Tumor cells form mouse in lab cultures</p>
16 Sep 2011

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One of the main problems in oncology is the lack of specificity of current treatments and the emergence of resistance.

Experts from all over the world meet up in Barcelona to discuss new strategies in the fight against cancer. These strategies may be crucial in turning cancer into a chronic disease.

On 19, 20 and 21 September the Institut d’Estudis Catalans (IEC) is to host the Barcelona Biomed Conference entitled “Signal rewiring and addiction in cancer”, in which scientists from all over the world will...

Institutional news
9 Sep 2011

Iproteos has been a semi-finalist in the II Award for the Best Entrepreneurial Biotechnology Project, a technology transfer prize given by the Spanish Society of Biochemistry (Sociedad Española de Bioquímica (SEBBM)). The spin-off, which is promoted by IRB Barcelona –located at the Barcelona Science Park- and the University of Barcelona –through the Bosch y Gimpera Foundation, also at the Park – was founded in June with the mission to develop and commercialize a new generation of more efficient low cost drugs with fewer side effects.

 

Scientific news
<p>Structure of NCBD when it is not bound to any other protein</p>
8 Sep 2011

Proteins, the molecular machines that carry out the majority of the functions within a cell, are typically seen as possessing a specific three-dimensional structure. Cellular processes (e.g. reproduction) are activated or deactivated by a molecular choreography that involves the binding of one protein to another. Of late, it has been recognized that even a small protein (say, of size 50 residues) can binding to multiple partners – this results in an advantageous situation for the cell wherein depending on the identity of the partner a different functional response can be generated. In parallel, it has become increasingly evident that a single static structure is a poor representation...

Scientific news
<p>Individual intestinal stem cells generate spherical organoids when grown in lab-plates (upper pannel). Under the microscope (lower pannel), these organoids reveal to be composed mostly by undiferentiated and proliferative cells, the intestinal stem cells</p>
4 Sep 2011

Human colon stem cells have been identified and grown in a lab plate for the first time. This achievement, made by researchers in the Colorectal Cancer Lab at the Institute for Research in Biomedicine (IRB Barcelona) and published in Nature Medicine, is a crucial advance towards regenerative medicine.

Scientific news
<p>Interneuron obtained from an engineered mouse lacking the malin gene (in green) and showing the accumulation of Lafora bodies (in red).</p>
29 Aug 2011

Using a mouse model, researchers at IRB Barcelona have demonstrated a link between abnormal sugar accumulation and the neuronal degeneration characteristic of Lafora disease. The study may contribute to understanding the origin and progression of Lafora and other neurodegenerative pathologies.

Scientific news
<p>The localization of CenH3 protein in the centromere (upper panel) becomes inespecific along the chromosome (lower panel) when its regulated degradation is unpaired.</p>
25 Aug 2011

Researchers at IRB Barcelona discover a crucial mechanism controlling the segregation of genetic material from parent to daughter cells. A finely tuned process of degradation tightly regulates CenH3 protein levels to ensure the correct function of the cell division machinery in Drosophila.