News

Scientific news
<p>Left, atomic structure of RNA polymerase I in its inactive form - homodimer; Right, atomic structure of RNA polymerase I in its active form -heterodimer with Rrn3-. (Carlos Fernández-Tornero CIB/CSIC and Oriol Gallego, IRB Barcelona)</p>
16 Mar 2017

Researchers unveil a mechanism responsible for halting protein synthesis when cells are deprived of nutrients.

The cell regulates its growth by forming various assemblies of RNA polymerase I.

The study has implications for cancer research.

Scientific news
<p>The image shows tumour cells infected by the virus, which expresses a fluorescent protein. Over the days (in the image fifth day), the virus multiplies, generating new virions that infect more cancer cells (IDIBAPS, IRB Barcelona)</p>
16 Mar 2017

IDIBAPS and IRB Barcelona researchers show the effectiveness of a new strategy to achieved genetically modified viruses that infect only tumor cells, thus preserving healthy tissues.

It is an innovative approach that exploits the different expression profiles of certain proteins between tumor and healthy cells, thus allowing the virus to infect only the former.

 

Institutional news
<p>Scheme of therapeutic concept designed by IRB Barcelona. The protein frataxina binds to peptide shuttle (blue), allowing the protein to cross the blood brain barrier and reach the brain (IRB Barcelona)</p>
14 Mar 2017

IRB Barcelona starts a project with the long-term goal to achieve an injectable frataxin treatment able to reach the brain.

Frataxin is the protein that is reduced in those affected by this rare and degenerative disease, which has no cure.

The patients’ associations Babel Family and ASOGAF in Granada provide the funding for the initial 18 months of this challenge.

Scientific news
<p>After chemotherapy, quiescent cells change their  behaviour​, become active​ ​and regenerate all cell types in the intestine (in green). (F Barriga, IRB Barcelona)</p>
9 Mar 2017

These comprise a small group of passive stem cells—quiescent—that are activated when needed and have the capacity to produce any kind of intestinal cell.

Quiescent cells are relevant for tissue regeneration and for their participation in tumour development.

Institutional news
<p>Marc Liesa, 2017 IRB Barcelona Alumni of Excellence Award.</p>
28 Feb 2017

Marc Liesa received his PhD in 2008 after completing his doctoral studies in Antonio Zorzano's Complex Metabolic Diseases and Mitochondria Laboratory.

This award recognises the excellence of former IRB Barcelona scientists.

The jury for the prize acknowledges Marc Liesa’s important contributions to mitochondrial biology.

Institutional news
<p>LegoLish-Mot, the second prototype of LEGOLish. Image: Julien Colombelli, Core Facility Manager of the Advanced Digital Microscopy Laboratory at IRB Barcelona.</p>
23 Feb 2017

IRB Barcelona is to participate in the first edition of YoMo Barcelona by giving a Lego fluorescence microscope workshop on March 1.

It is a unique and creative project that brings the latest 3D imaging technology to schools, high schools and universities.

Julien Colombelli, co-inventor of the microscope and Core Facility Manager of the Advanced Digital Microscopy Laboratory, will be coordinating the workshop.

Institutional news
<p>The fundraising campaign called "Future" (#IRBfutur) was launched at the end of 2016 to raise public awareness of the role that biomedical research plays in advancing medicine (L.T. Barone, IRB Barcelona)</p>
21 Feb 2017

The positive public response to the "Futur" fund-raising campaign launched by IRB Barcelona towards the end of 2016 sets the stage for a new "IRB Barcelona Futur PhD Fellowship".

The fellowship will allow a young researcher to join an IRB Barcelona lab to do a 4-year doctoral thesis.

Institutional news
<p>The third edition of the PhD4MD programme is launched today</p>
17 Feb 2017

Research centres of excellence in Barcelona offer PhD fellowships to medical doctors.

Called PhD4MD, the programme allows medical doctors to carry out a three-year doctoral thesis on cancer, rare disease or neurodegenerative conditions.

Institutional news
<p>Marco Milán.</p>
15 Feb 2017

The “Meet Our Scientists” video entitled “Our relative the fly” presents the research performed by Marco Millán on the fruit fly.

He studies the cellular and molecular mechanisms underlying the regulation of tissue growth during normal development, its proper functioning and the formation of a tumour.

Institutional news
<p>Merus N.V. is a clinical-stage immuno-oncology company developing innovative bispecific antibody therapeutics.</p>
9 Feb 2017

The research collaboration will combine Merus’ Biclonics technology platform and unique cell and animal models at the Colorectal Cancer Laboratory led by Eduard Batlle to investigate the stroma.