A conference organised by IRB Barcelona and the BBVA Foundation brings together leading international researchers devoted to two cell organelles that play key roles in health and disease.
Cancer and certain developmental disorders are characterised by impaired activity of these complex cell structures and defects in cell cycle control.
The Asociación Española Contra el Cáncer (AECC) presents a prize for a study that reveals the capacity of the CPEB4 protein to prevent fatty liver disease.
The research was led by Raúl Méndez from IRB Barcelona and Mercedes Fernández from IDIBAPS.
This weekend the Ciutadella Park will be hosting this event, which will showcase 230 scientific activities aimed at the general public.
IRB Barcelona will be participating through two workshops and a micro-talk, related to microscopy, cancer research and ageing.
Jordi Casanova from IRB Barcelona wrote an opinion article in EMBO Journal.
The author highlights that scientists should be aware of the limitations of models and categories.
The video series Meet Our Scientists presents Travis Stracker, head of the Genomic Instability and Cancer lab at IRB Barcelona.
The video “Maintaining stability of the genome” highlights the research underway to unravel how cells prevent genomic instability.
A study on breast cancer conducted at IRB Barcelona identifies the key role of p38 in safeguarding tumour cells against the excessive accumulation of DNA damage, which would otherwise cause cell death.
p38 blockage has been shown to increase the death of tumour cells, thus causing tumours to shrink.
The combination of p38 inhibitors with chemotherapeutic drugs (taxanes) strengthens, accelerates or prolongs the antitumour effect in patient-derived tumours grown in mice.
For the scientific community, the protein POP (prolyl oligopeptidase) is an attractive therapeutic target for the treatment of cognitive and neurodegenerative disorders.
Scientists at IRB Barcelona have developed the first POP inhibitors that are irreversible, selective and brain-permeable.
Nine scientists at IRB Barcelona form part of EMBO, an organisation that comprises more than 1,800 outstanding researchers from Europe and around the world specialised in molecular biology.
“This will allow me to strengthen interactions with other European researchers, as well as to stay abreast of new ideas, concepts and technologies,” says Aznar Benitah.
BIST has selected 12 winners, among them Guiomar Solanas, Jelena Urosevic and Lidia Mateo.
This programme recognises excellence in research and supports women scientists in their transition to leadership positions.
The study, published in The Journal of Cell Biology, focuses on the development of the sperm tail, the structure that enables sperm cells to swim and is therefore critical for male fertility.