Researchers unveil a mechanism responsible for halting protein synthesis when cells are deprived of nutrients.
The cell regulates its growth by forming various assemblies of RNA polymerase I.
The study has implications for cancer research.
IDIBAPS and IRB Barcelona researchers show the effectiveness of a new strategy to achieved genetically modified viruses that infect only tumor cells, thus preserving healthy tissues.
It is an innovative approach that exploits the different expression profiles of certain proteins between tumor and healthy cells, thus allowing the virus to infect only the former.
IRB Barcelona starts a project with the long-term goal to achieve an injectable frataxin treatment able to reach the brain.
Frataxin is the protein that is reduced in those affected by this rare and degenerative disease, which has no cure.
The patients’ associations Babel Family and ASOGAF in Granada provide the funding for the initial 18 months of this challenge.
These comprise a small group of passive stem cells—quiescent—that are activated when needed and have the capacity to produce any kind of intestinal cell.
Quiescent cells are relevant for tissue regeneration and for their participation in tumour development.
Marc Liesa received his PhD in 2008 after completing his doctoral studies in Antonio Zorzano's Complex Metabolic Diseases and Mitochondria Laboratory.
This award recognises the excellence of former IRB Barcelona scientists.
The jury for the prize acknowledges Marc Liesa’s important contributions to mitochondrial biology.
IRB Barcelona is to participate in the first edition of YoMo Barcelona by giving a Lego fluorescence microscope workshop on March 1.
It is a unique and creative project that brings the latest 3D imaging technology to schools, high schools and universities.
Julien Colombelli, co-inventor of the microscope and Core Facility Manager of the Advanced Digital Microscopy Laboratory, will be coordinating the workshop.
The positive public response to the "Futur" fund-raising campaign launched by IRB Barcelona towards the end of 2016 sets the stage for a new "IRB Barcelona Futur PhD Fellowship".
The fellowship will allow a young researcher to join an IRB Barcelona lab to do a 4-year doctoral thesis.
Research centres of excellence in Barcelona offer PhD fellowships to medical doctors.
Called PhD4MD, the programme allows medical doctors to carry out a three-year doctoral thesis on cancer, rare disease or neurodegenerative conditions.
He studies the cellular and molecular mechanisms underlying the regulation of tissue growth during normal development, its proper functioning and the formation of a tumour.
The research collaboration will combine Merus’ Biclonics technology platform and unique cell and animal models at the Colorectal Cancer Laboratory led by Eduard Batlle to investigate the stroma.