A study published today in the Journal of National Cancer Institute (JNCI) by ICREA researcher Roger Gomis may be key to the early detection of patients at risk of developing metastasis to the bone
This new knowledge may accelerate the development of the first preventive treatment of bone metastasis
Inbiomotion, an IRB Barcelona spin off company and financed with venture investors Ysios Capital, has already begun clinical trials
Scientists at IRB Barcelona publish the details of an old tissue transplant method for Drosophila melanogaster.
This technique allows the study of tumour growth and tissue regeneration
A study conducted in collaboration with the CSIC, BSC and UB provides a new approach to follow cellular proteins more closely.
The target proteins labelled with inntags do not show detectable alterations of function or localization.
Researchers at IRB Barcelona unravel a role for tumour suppressor genes in restricting the growth of neighbouring cell populations.
The study, published yesterday in PLoS Biology, might have implications for understanding the early events of tumorigenesis and the selection of the tumour-initiating cells.
The study, published in Current Biology, focuses on cilia, the cellular structures that by sensing chemicals and mechanical forces allow for smelling, hearing, and many other essential functions.
Researchers at IRB Barcelona reveal that the protein E-Cadherin is required for groups of diverse cells to migrate together
Tumours with intermediary levels of E-Cadherin generally have a poorer prognosis; the phenomenon of heterogeneous cell migration may be related to this
Researchers at IRB Barcelona discover the molecular mechanism that determines how epigenetic markers influence gene expression
Combination of two strong denaturants of DNA leads to stabilization of the structure
An unexpected finding that opens new fields to the biotechnological use of DNA
A study, published today in the journal Nature, marks a milestone in the understanding of chronic lymphocytic leukemia (CLL)
CLL is the most frequent leukemia with more than 12,000 new cases diagnosed in Europe every year
IRB Barcelona group leader Modesto Orozco participated in the study as he is involved with the International Cancer Genome Consortium (ICGC)
Maria Macias, Pau Martín, and Joan Massagué publish a featured review article in Trends in Biochemical Sciences (TIBS) on the Smad protein family, the members of which play a key role in cancer.
The article is accompanied by a web application in which available 3D structures of Smads can be explored, as can their alterations in several metazoa, their variability in humans, and their mutations in tumours.