In studies conducted on the fruit fly, researchers at IRB Barcelona headed by ICREA Professor Marco Milán have revealed that organs have the molecular mechanisms to control their proportions. In this process the protein p53 plays a crucial role. The study is published today in the prestigious journal PLoS Biology.
The correct establishment of organ proportions, which occurs during embryonic development, is vital for the proper function of all organisms. Alterations in the mechanisms responsible for these processes cause fatal errors in embryos and even cause their death. In the Renaissance period, Leonardo da Vinci, in his famous picture of the “Vitruvian man...
The protein DOR controls the maturation of adult flies depending on availability of nutrients
Scientists at IRB Barcelona develop a computational strategy to identify potential protein interaction partners regulated by Aurora A kinase.
Scientists at IRB Barcelona have provided new data on how certain types of aggressive breast cancer bypass tumour suppression mechanisms.
In collaboration with the Barcelona Science Park (PCB), IRB Barcelona will be participating in Science Week, the largest public communications event on science and technology in Spain, which this year reached its 15th series. Coordinated by the “Fundació Catalana per a la Recerca i la Innovació” (FCRI), the programme of activities will be held from 12 to 22 November.
The activities include open days on 16 and 18 November. Entitled “Come and do an express PhD”, through a series of clues visitors will analyse the differences between malignant and benign tumour cells. In this regard, they will visit Eduard Batlle’s lab, the Advanced Digital Microscopy Platform and the “Centro...
The new data base, which includes 1,700 proteins in motion, allows a more efficient design of drugs.
MoDEL holds 30% of human therapeutic targets and the objective is to cover 80% in three years.
This finding has brought them the “Paper of the week” of the Journal of Biological Chemistry, one of the journals of greatest impact in basic biology.
Called SLIMP, the protein is required for mitochondria maintenance, the cellular powerhouses.
In the journal Science Signaling, Andreu Casali describes a sophisticated mechanism related to the protein Hedgehog.
Researchers at IRB Barcelona have discovered this with the human cytomegalovirus, the most deadly and widespread herpesvirus and the cause of serious defects in neonates.
The prediction of the structure and function of biological macromolecules (i.e., the machinery of life) is of foremost importance in the field of structural biology.