Unless you are a molecular biologist, you may not have heard the term ubiquitin. Given its essential role in the cell, however, it is likely that its protagonism and popularity will increase. One of the processes in which ubiquitin plays a relevant role is in the degradation of proteins. In the cell, the generation of proteins is just as important as their destruction, as well as the maintenance of a correct balance between both processes.
Proteins become candidates for degradation when they are defective, when they have completed their function and are no longer necessary, or when they belong to pathogenic organisms. Ubiquitin attaches itself to these proteins as if it were an...
The role of chromatin and histones in the regulation of DNA
Researchers have transferred the patent to the biotech enterprise Genmedica Therapeutics.
What would motivate anyone to wake up early on a lazy springtime weekend morning, get dressed, and head to town? Research, of course! Fifty would-be scientists made their way to the Caixa Catalunya Cultural Centre in the "Pedrera" building in Barcelona on Saturday, March 3 for a day filled with science and fun. The occasion was Fes Recerca!, a series of hands-on science workshops aimed at the general public. The events, organized by the Parc Cientific de Barcelona over four weekends in February and March, provide an opportunity for amateur science buffs to experience what it is like to do research and learn about science...
Their work appears online this week in Proceedings of the National Academy of Sciences USA.
The study appears this week in the scientific journal Developmental Cell.
Biocomputation, with supercomputers as key tools, is allowing scientists to respond to many unanswered questions about these crucial agents for life.
The study appears in this week’s online version of the prestigious scientific journal Proceedings of the National Academy of Sciences.
Just a few decades ago, ribonucleic acid (RNA) molecules were considered simple intermediaries between DNA, the protagonist of genetics, and proteins, the products of genes. RNA is now proving to play an important role in gene transcription and regulation, processes which are key to understanding how an organism develops and functions.
The study of ribonucleic acid molecules has provided many surprises, the most revolutionary being the mechanism of gene silencing, or RNA interference (RNAi). This discovery has had far-reaching repercussions in laboratories across the world, not only because the novelty of the mechanism, but also because it has enormous potential for clinical...
Although the ways in which tumours spread and cause death remain an enigma, recent studies have provided significant data.