On Tuesday 8 June, Dr. Eduard Batlle, head of the Colorectal Cancer lab at IRB Barcelona, ICREA researcher, and group leader at CIBER Cancer (CIBERONC), received the Rei Jaume I Prize for Medical Research. The Rei Jaume I prizes acknowledge people who have carried out highly significant work which has mostly been undertaken in Spain. The prizes are given each year and awardees are presented with a gold medal, a diploma and €100,000 - to be reinvested largely in research.
Dr. Toni Gabaldón, ICREA Research Professor and group leader at the Institute for Research in Biomedicine (IRB Barcelona) and the Barcelona Supercomputing Center (BSC-CNS), has been elected to become an EMBO member. This year, 64 leading life scientists have been appointed new EMBO Members and Associate Members, joining a community of more than 1,800 leading life scientists.
All the cells of an organism share the same DNA sequence, but their functions, shapes or even lifespans vary greatly. This happens because each cell “reads” different chapters of the genome, thus producing alternative sets of proteins and embarking on different paths. Epigenetic regulation—DNA methylation is one of the most common mechanisms—is responsible for the activation or inactivation of a given gene in a specific cell, defining a secondary cell-specific genetic code.
Cells have to constantly adapt to their surroundings in order to survive. A sudden increase in the environmental levels of an osmolyte, such as salt, causes cells to lose water and shrink. In a matter of seconds, they activate a mechanism that allows them to recover their initial water volume and avoid dying.
Open call for Postdoctoral Candidates to apply for 2021 Cris contra el Cancer - PostDoc Talent
Running from July to September 2021, the Maths4Life Programme is aimed at outstanding and highly motivated BSc and MSc students with a strong interest in mathematics and statistics.
It is important to understand which conformational changes are produced upon small-molecule binding or which molecules can bind target proteins better than their own natural ligands, as per improving biotherapeutic design. IRB Barcelona has skilled scientific staff in techniques from bioinformatics simulations to biophysical or spectroscopic analysis and can apply them to evaluate the structural changes behind an observed experimental observation. Furthermore, the institute can bring together complementary techniques as per addressing complex questions and projects.