Complex metabolic diseases and mitochondria news

<p>Cells with elongated mitochondrial network in red. Image: David Sebastián, IRB Barcelona</p>
18 Jan 2018

A team headed by Antonio Zorzano at IRB Barcelona has identified activators of the mitochondrial protein Mitofusin 2 for the treatment of type 2 diabetes.

The protein is a key regulator of many mitochondrial functions, as well as of the cell as a whole.

<p>Jordi Coste (on the right of the image), accompanied by the "A future in biomedicine" 2015 students: Pau de Jorge, Anna Ferrer, Eduard Puig and Enric Ros (from left to right).</p>
31 Oct 2017

After spending three years as a Visiting Student in the Complex Metabolic Diseases and Mitochondria Lab led by Antonio Zorzano, Jordi Coste (b. Barcelona, 1993) is about to embark on new projects in the United States. This young scientist is leaving behind what he considers “a big family” at IRB Barcelona to pursue a career more focused on clinical counselling. But before crossing the pond, he has found time to look back on his years with us: “The Institute has helped me to improve my critical and logical thinking skills, and this will definitely help me in the future.”

17 Oct 2017

Professor Antonio Zorzano is the president of the FEBS3+ Congress as well as programme head at IRB Barcelona and the Diabetes and Associated Metabolic Diseases Networking Biomedical Research Centre (CIBERDEM).

17 Oct 2017

Several media, including Canal Diabetes, has dedicated an article to the first joint meeting of the French, Portuguese and Spanish Biochemistry and Molecular Biology Societies (FEBS3+), which will take place in the Palau de Congressos of the Fira de Barcelona from 23 to 26 October. Gathering top scientists, the meeting will be presided by Antonio Zorzano, group leader at IRB Barcelona and coordinator of the Molecular Medicine Programme, as well as professor at the University of Barcelona and CIBER for Diabetes and Associated Metabolic Diseases.

Link to Canal Diabetes

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<p>Marc Liesa recommends that young scientists make career decisions based solely on what truly inspires and motivates them.</p>
19 Jul 2017

The 2017 IRB Barcelona Alumni of Excellence Award has gone to Marc Liesa, who obtained his PhD in 2008 in Antonio Zorzano’s Complex Metabolic Diseases and Mitochondria Laboratory. The award, established in 2016, acknowledges the excellence of former IRB Barcelona scientists and is given with the support of Eppendorf. Liesa visited the Institute on 5 May to receive the distinction. He talks about his science and shares some secrets of his success.

 

<p>Fluorescence microscopy image of the hypothalamus arcuate nucleus with POMC neurons in green (Image: Alicia G Gómez-Valadés).</p>
27 Jun 2017

Radio 5 (RNE) interviews Marc Claret, head of the Neuronal Metabolism Control Group at the August Pi i Sunyer Biomedical Research Institute – IDIBAPS, on the occasion of his recent study on the connection between the hypothalamus and pancreas. 

Published in Cell Metabolism, this work is co-authored by Antonio Zorzano, group leader of the Complex Metabolic Diseases and Mitochondria Laboratory at IRB Barcelona, and Marc Claret.

The study reveals the connection between POMC neurons in the hypothalamus and insulin release by the pancreas and describes new molecular mechanisms involved in this process, thereby contributing to a greater understanding of diabetes. "This...

<p>Image: Diabetes UK.</p>
8 Jun 2017

The Global Diabetes Community, Diabetes UK, echoes on the study performed by IRB Barcelona and IDIBAPS scientists. In the study, the researchers reveal the link between POMC neurons in the hypothalamus and the release of insulin by the pancreas. 

Published in Cell Metabolism, this work emphasises the relevance of neuronal mechanisms in the detection of nutrients and the regulation of glucose levels.

Link to Diabetes UK

<p>Fluorescence microscopy image of the hypothalamus arcuate nucleus with POMC neurons in green (Image: Alicia G Gómez-Valadés).</p>
7 Jun 2017

A study co-led by IRB Barcelona and IDIBAPS emphasizes the importance of the neuronal mechanisms in the detection of nutrients and the control of glucose levels.

The results published in Cell Metabolism help to understand diabetes in greater detail.

<p>Fluorescence microscopy image of the hypothalamus arcuate nucleus with POMC neurons in green (Image: Alicia G Gómez-Valadés).</p>
7 Jun 2017

Several media have echoed the research co-chaired by Marc Claret, at the August Pi i Sunyer Biomedical Research Institute – IDIBAPS, and Antonio Zorzano, group leader of the Complex Metabolic Diseases and Mitochondria Laboratory at IRB Barcelona. The study reveals the connection between POMC neurons at the hypothalamus and insulin release by the pancreas and describes new molecular mechanisms involved in this process. 

Published in Cell Metabolism, this study contributes to a greater understanding of diabetes.

Link to...

<p>3D illustration of fat cells. Image: RTVE.</p>
6 Jun 2017

Various media, including the Spanish TV channel RTVE, have echoed the research performed by scientists at the Institute of Biomedicine of the UB (IBUB) on a new technique that measures the production and use of energy in brown adipose tissue, a key aspect in the development of obesity. 

Published in the journal 'Advanced Science', this work involved the collaboration of Antonio Zorzano, group leader of the Complex Metabolic Diseases and Mitochondria Laboratory at IRB Barcelona, and David Sebastián, research associate in the same lab. 

Link to ...