Complex metabolic diseases and mitochondria news

<p>Mouse cells with DOR protein. (M. Romero, IRB Barcelona)</p>
19 Apr 2018

Researchers at IRB Barcelona discover the mechanism that leads to a less harmful form of obesity that is associated with the number rather than volume of fat cells.

There are several types of obesity and some are more harmful than others.

The study has been published in the journal Nature Cell Biology.

<p>Antonio Zorzano, head of the Complex Metabolic Diseases and Mitochondria Lab</p>
13 Apr 2018

Gen magazine, Phys Org, News Medical Life Sciences, among other international media, have published an article on the latest study led by Antonio Zorzano from IRB Barcelona, which supports the notion that mitochondrial defects underlie a set of diseases of unknown origin that involve chronic muscle inflammation.

Link to GEN

Link to Phys Org

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<p>Image: University of Barcelona</p>
13 Apr 2018

The new study analyses the dysfunction of basolateral transporters through a transgenic animal model.

This study is led by Manuel Palacín from IRB Barcelona and Virgínia Nunes from IDIBELL.

<p>Image: La Vanguardia</p>
11 Apr 2018

La Vanguardia has published an article about the "Vanguardia de la Ciencia" award ceremony. The winners of these awards were selected by readers, who vote among eight Spanish researchers in the field of physics, chemistry, biology and social sciences. Marc Claret, at IDIBAPS, and Antonio Zorzano, at IRB Barcelona, came third for their research on the connection between the hypothalamus and the pancreas.

Link to La Vanguardia

<p>Mitochondrial DNA stress (in red) triggers the inflammatory response in mouse muscle cells devoid of Opa1 (nuclei in green). Aida Rodríguez, IRB Barcelona</p>
9 Apr 2018

A study performed at IRB Barcelona supports the notion that mitochondrial defects underlie a set of diseases of unknown origin that involve chronic muscle inflammation.

<p>Image: La Vanguardia</p>
6 Mar 2018

La Vanguardia newspaper has published an article congratulating the winners of the "Vanguardia de la Ciencia" Award. The third place went to the research done by Marc Claret, at IDIBAPS, and Antonio Zorzano, head of the Complex Metabolic Diseases and Mitochondria Laboratory at IRB Barcelona. This study, discovered that a small group of neurons communicates with the pancreas to regulate the release of insulin. This finding thus, represents an advance in the understanding of type 2 diabetes.

Link to La Vanguardia

<p>Image: La Vanguardia</p>
5 Mar 2018

La Vanguardia newspaper published an article about the winners of the "Vanguardia de la Ciencia" Award, organised by the same newspaper and the Catalunya-La Pedrera Foundation. A study by Marc Claret from IDIBAPS and Antonio Zorzano from IRB Barcelona revealing that a small group of neurons communicates with the pancreas to regulate the release of insulin got third place. This finding is an advance in the understanding of type 2 diabetes.

Link to La Vanguardia

<p>Image: La Vanguardia</p>
30 Jan 2018

Antonio Zorzano from IRB Barcelona and Marc Claret from IDIBAPS have been nominated for the “Vanguardia de la Ciencia” award. Their research reveals the connection between the hypothalamus and pancreas.

Link to La Vanguardia

<p>Cells with elongated mitochondrial network in red. Image: David Sebastián, IRB Barcelona</p>
23 Jan 2018

La Vanguardia, La Razón, Correo Farmacéutico, Health Canal, among other national and international media, have published an article about the research led by Antonio Zorzano, from IRB Barcelona, and Fernando Albericio, from the University of Barcelona. This study reveals activators of mitochondrial protein Mitofusin 2 that may be valuable in the treatment of type 2 diabetes.

Link to La Vanguardia

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<p>Cells with elongated mitochondrial network in red. Image: David Sebastián, IRB Barcelona</p>
18 Jan 2018

A team headed by Antonio Zorzano at IRB Barcelona has identified activators of the mitochondrial protein Mitofusin 2 for the treatment of type 2 diabetes.

The protein is a key regulator of many mitochondrial functions, as well as of the cell as a whole.