Development and Growth Control Laboratory news

<p>Drosophila epithelium subjected to chromosomal instability (CIN): cells start invading the neighbouring tissues. Magenta labels the nuclei of all the epithelium while green labels the membranes of cells subjected to CIN (L Barrio, IRB Barcelona)</p>
1 Oct 2018

La Vanguardia, Biotech, Salud y Medicina, among other media, have published an article on the study led by IRB Barcelona researcher Marco Milán. The study shows that chromosomal instability itself can induce invasive behaviour in epithelial cells, and identifies the underlying molecular mechanisms involved.

Link to La Vanguardia

Link to Biotech...

<p>Drosophila epithelium subjected to chromosomal instability (CIN): cells start invading the neighbouring tissues. Magenta labels the nuclei of all the epithelium while green labels the membranes of cells subjected to CIN (L Barrio, IRB Barcelona)</p>
26 Sep 2018

Most solid tumours with metastatic potential show a high degree of chromosomal instability.

A study published in the journal Developmental Cell demonstrates that chromosomal instability itself promotes invasive behaviour.

The researchers identify the oncogene Fos and the tumour suppressor Capicua as necessary molecular elements mediating this invasive behaviour.

26 Sep 2018

La Vanguardia reports on a recent study published by Marco Milán’s lab in the journal Developmental Cell. On the basis of their findings in the fruit fly (Drosophila melanogaster), the scientists have concluded that the chromosomal instability characteristic of tumours can promote invasive behaviour in cancer.

Link to La Vanguardia: Demuestran que la inestabilidad cromosómica de tumores promueve la metástasis (in Spanish)

<p>Image: La Pedrera</p>
6 Jul 2018

BIYSC 2018 starts with 90 students from all over the world.

IRB Barcelona receives today eight students that will participate through the workshop "Drosophila melanogaster: a model to study human disease".

<p>Joan Massagué, director of the Sloan Kettering Institute of New York. Image: Jordi Casañas (Mahala, IRB Barcelona)</p>
15 Mar 2018

High-ranking figures from the business and innovation sectors attended an event organised by IRB Barcelona and ESADE with the aim to highlight the importance of uniting all sectors of society against metastasis.

<p>Colon cancer stem cells, in green (G. Turon, IRB Barcelona)</p>
13 Mar 2018

Advances in research into the immunological evasion, metabolism and latency of metastatic cancer cells allow the identification of potential targets to test therapies.

IRB Barcelona and the BBVA Foundation invite 20 renowned international scientists working in the field of cancer metastasis to a gathering in Barcelona.

After the scientific conference, IRB Barcelona and ESADE have organised a debate on how to translate scientific research to society.

21 Dec 2017

Diario de León has published an article about the award (Imagen Positiva de la Juventud de Castilla y León) given to Celia Santos (León, 1991), a PhD student in the Development and Growth Control Laboratory at IRB Barcelona for the project “Noies al Lab” (Girls to the lab), which aims to promote scientific vocation among girls. 

Link to Diario de León

<p>In this mouse embryo structures can be observed that contain neurofilament, stained cyan, and E-Cadherin, in magenta, showing, respectively, the nervous system and internal organs (Authors:  Jim Swoger, Jürgen Mayer, Laura Quintana. CRG 2017)</p>
27 Nov 2017

The European Molecular Biology Lab (EMBL) in Barcelona and IRB Barcelona bring together leading scientists in the conference “Morphogenetic Engineering”, an event supported by the BBVA Foundation.

The merge of various disciplines of developmental biology is key to enhancing our knowledge of tissue development and repair, processes that find their most direct applications in regenerative medicine.

“One day we will be able to re-build damaged organs and keep the whole body fit and healthy. But right now we must strengthen our knowledge of how tissues are built and how they are maintained,” say James Sharpe, Head of EMBL Barcelona, and Marco Milán, coordinator of the Cell and Developmental Biology programme.

27 Nov 2017

Fifteen media outlets, including El Periódico de Catalunya, ABC and La Vanguardia, have published an article on the BioMed conference on morphogenetic engineering, which was held from November 27 to 29. The gathering brought together specialists from multiple fields related to development biology with the aim to advance understanding of the generation and repair of organs and tissues.

Media selection:

Link to El Periódico de Catalunya

Link to...

<p>Tumour (red) covered by collagen (green), which is being deposited by cells of the immune system (cyan). (Image: Mariana Muzzopappa, IRB Barcelona)</p>
11 Sep 2017

Several media, including Periodistas en Español, have highlighted the research performed by the group headed by ICREA Professor Marco Milan. The study reveals the ability of tumours of epithelial origin to grow in the absence of a tumour microenvironment. The researchers examined the growth of a tumour in the absence of adjacent cell populations like the immune system or mesenchymal cells.

Link to ...