Development and Growth Control Laboratory news

<p>Tumour (red) covered by collagen (green), which is being deposited by cells of the immune system (cyan). (Image: Mariana Muzzopappa, IRB Barcelona)</p>
11 Sep 2017

Several media, including Periodistas en Español, have highlighted the research performed by the group headed by ICREA Professor Marco Milan. The study reveals the ability of tumours of epithelial origin to grow in the absence of a tumour microenvironment. The researchers examined the growth of a tumour in the absence of adjacent cell populations like the immune system or mesenchymal cells.

Link to ...

<p>Tumour (red) covered by collagen (green), which is being deposited by cells of the immune system (cyan). (Image: Mariana Muzzopappa, IRB Barcelona)</p>
7 Sep 2017

Researchers at IRB Barcelona reveal the capacity of epithelial-derived tumours to grow in the absence of a microenvironment.

Featured on the cover of the journal Proceedings of the National Academic of Sciences (PNAS), the study identifies the cell types and molecular mechanism involved in tumour initiation and growth.

The results of this study contribute to our understanding of the internal mechanisms of the tumour, which may provide a therapeutic target.

<p>IRB Barcelona will host students for a research project on the fruit fly (Drosophila melanogaster).</p>
10 Jul 2017

IRB Barcelona is to participate in the two-week (10-21 July) scientific summer camp through the project “Drosophila melanogaster: a model to study human disease”.

This initiative is organised by the Catalunya-La Pedrera Foundation, in collaboration with first-class research centres all over Catalonia, including BIST centres. 

<p>The top and bottom of the image show how the Dpp concentration gradient affects the organisation of the wing structure of Drosophila melanogaster. In the centre, in the absence of Dpp, the wing does not grow. Image: Lara Barrio.</p>
5 Jul 2017

Scientists at IRB Barcelona clarify the function of the genes that drive wing development in the fruit fly Drosophila melanogaster.

Published in the journal eLife, this study unveils that the Dpp morphogen is necessary for wing growth but that its gradient does not govern this process.

Understanding the development of limbs in Drosophila paves the way to research into congenital defects in vertebrates.

<p>The fruit fly (Drosophila melanogaster), a means to model and study human disease.</p>
23 Mar 2017

100 secondary school students aged between 16 and 18 years old will have the chance to experience the Barcelona International Youth Science Challenge (BIYSC) 2017.

It is a two-week (10-21 July) scientific summer camp organised by the Catalunya-La Pedrera Foundation in collaboration with first-class research centres all over Catalonia.

The registration period is now open for BIYSC, in which IRB Barcelona coordinates a project in biomedicine.

<p>Teachers and scientists working together.</p>
17 Mar 2017

IRB Barcelona is to participate in the twelfth edition of the Catalunya La Pedrera Foundation's Teachers and Science Programme.

Teachers will work alongside the scientists to develop resources that can be taken back to the classroom.

<p>Marco Milán.</p>
15 Feb 2017

The “Meet Our Scientists” video entitled “Our relative the fly” presents the research performed by Marco Millán on the fruit fly.

He studies the cellular and molecular mechanisms underlying the regulation of tissue growth during normal development, its proper functioning and the formation of a tumour.

13 Jan 2017

"Gaceta Médica” devotes an article to the study headed by ICREA Professor Marco Milán. Published in Nature Communications, the study identifies a fundamental role of the JAK/STAT signalling pathway in the development and growth regulation of limbs in Drosophila.

Link to Gaceta Médica

<p>Ectopic wings upon ectopic activation of JAK/STAT (Carles Recasens-Alvarez and Ana Ferreira, IRB Barcelona)</p>
9 Jan 2017

Researchers at IRB Barcelona identify a fundamental role of the JAK/STAT signalling pathway in the development and growth regulation of limbs in Drosophila.

Published in Nature Communications, the study paves the way to research into the function of this pathway in vertebrate development and its possible involvement in human congenital diseases.

9 Jan 2017

Various media report on the study headed by ICREA Professor Marco Milán, leader of the Development and Growth Control Lab at IRB Barcelona. The study discloses a new signal that participates in the specification and growth of fruit fly (Drosophila melanogaster) wings.

Published in Nature Communications, this work paves the way to research into the function of this pathway in vertebrate development and its possible involvement in human congenital diseases.

Link to ...