Development and Growth Control Laboratory news

<p>Flies with wings of different sizes but in proportion. © Milán Lab. IRB Barcelona.</p>
14 Dec 2010

In studies conducted on the fruit fly, researchers at IRB Barcelona headed by ICREA Professor Marco Milán have revealed that organs have the molecular mechanisms to control their proportions. In this process the protein p53 plays a crucial role. The study is published today in the prestigious journal PLoS Biology.

The correct establishment of organ proportions, which occurs during embryonic development, is vital for the proper function of all organisms. Alterations in the mechanisms responsible for these processes cause fatal errors in embryos and even cause their death. In the Renaissance period, Leonardo da Vinci, in his famous picture of the “Vitruvian man...

31 May 2010

The digital journal produced by the French Embassy in Spain, Bulletins Electroniques, reports on the scientific results produced by Marco Milan’s group that were published in EMBO Journal in May.

31 May 2010

The scientific journalist Pere Estupinyà has written an entertaining account in his blog in the newspaper El País “Science notes from MIT” about five researchers that he met during a visit he made to IRB Barcelona in May.

Read the article (in Spanish):

http://blogs.elpais.com/apuntes-cientificos-mit/2010/05/rep%C3%B3quer-de-ases-cient%C3%ADficos.html

29 Apr 2010

The study published by Marco Milán in the journal Embo Reports on the identification of a gene implicated in maintaining epithelial architecture has deserved a highlighted scientific comment in the same journal. The comment is made by Keith E Mostov, a renowned international cell biologist at the School of Medicine of the University of California San Francisco. Mostov draws attention to the novelty of the study and the need to address epithlial biology. In this regard, although this biology is important because of its relation with...

22 Apr 2010

In its Health Section, the digital journal “Consumer Eroski” reports on a study by Marco Milan published in EMBO Journal. This research reveals new data, obtained in the fly Drosophila, on the regulation of the oncoprotein Myc by microRNA machinery.

<p>Diagram of  Myc regulation by miRNAs. (c) Lab M. Milán.</p>
20 Apr 2010

The group led by Marco Milán, researcher at IRB Barcelona, discovers that microRNAs control the levels of the oncoprotein Myc in Drosophila.

14 Apr 2010

The front page of Diario Médico reports on research performed by Marco Milán, ICREA investigator at IRB Barcelona. His group has identified a new protein that contributes to epithelial stability.

<p>Laminin and Integrin localization in scarface mutant embryos.</p>
9 Apr 2010

Researchers at IRB Barcelona discover a new component required for the structural maintenance of the epithelium.

15 Mar 2010

Diario Médico reports on the study headed by Marco Milán, head of the Cell and Developmental Biology Programme at IRB Barcelona, and published in Current Biology.

<p>A graphic showing the opposite functions of Notch receptor.</p>
11 Mar 2010

The same molecule is also involved in cancer and studies of its activity may provide new clues for the design of effective therapies.