Many treatments against cancer, such as TRAIL, aim to trigger a type of cell death known as apoptosis.
A team at IRB Barcelona, headed by Antonio Zorzano, has demonstrated that the protein TP53INP2 induces apoptosis in chemotherapy treatments.
Jordi Casanova from IRB Barcelona wrote an opinion article in EMBO Journal.
The author highlights that scientists should be aware of the limitations of models and categories.
La Vanguardia, EFE, La Sexta, RTVE, among other media, have published articles about the study by Jordi Casanova, at IRB Barcelona, that reveals that the same genes can activate tumour growth and metastasis and that therefore some tumours are conferred metastatic capacity from their very outset.
Link to La Vanguardia
Link to EFE
In spite of the difference between the cell functions responsible for giving rise to a tumour and for the metastasis of this same tumour, studies at IRB Barcelona using the fly Drosophila melanogaster reveal that some genes can drive both phenomena.
The prize is shared between American scientists Jeffrey C Hall, Michael Rosbash and Michael W Young for work on the internal clock of living organisms, using the fruit flies for their research.
Their discoveries explain how plants, animals and humans adapt their biological rhythm to synchronise with the rotation of the Earth.
The biological clock helps to regulate sleep patterns, feeding behaviour, hormone release and blood pressure.
Salvador Aznar Benitah, scientist at IRB Barcelona studying the day-night cycle in adult stem...
IRB Barcelona is to participate in the twelfth edition of the Catalunya La Pedrera Foundation's Teachers and Science Programme.
Teachers will work alongside the scientists to develop resources that can be taken back to the classroom.
On the occasion of the Barcelona Biomed Conference on Plasticity and Cell Migration, scientists Jordi Casanova, co-organizer of the gathering, and Angela Nieto dealt with various specialized media.
From today and until Wednesday, 150 scientists from around the world will debate plasticity and cell migration in the new gathering in the Barcelona Biomed Conference Series, organised by IRB Barcelona and the BBVA Foundation.
The 28th conference in this series brings together biologists devoted to the study of development in animal models, specialists in cancer, and paediatricians.
Researchers working with flies at IRB Barcelona describe that the concentration of some small intracellular organelles determines the branching capacity of tracheal cells.
Tracheal cells are analogous to the cells that form blood vessels in the human body. The inhibition or stimulation of new blood vessels has implications in cancer and in tissue regeneration.
Changes in the regulation of two genes explain how the Drosophila respiratory system evolved from a primitive to a more developed state
Published in Development