Gene Translation Laboratory news

<p>Lluís Ribas, group leader at IRB Barcelona</p>
18 Jan 2019

La Sexta and Agencia Sinc, among other media, have published an article on the recent study by IRB Barcelona, led by ICREA researcher Lluís Ribas, who has discovered a mechanism that evolved in eukaryotic cells and that facilitates the synthesis of proteins, such as those present in the extracellular matrix. Of note, some of these proteins are highly relevant in biomedicine because of their link with diseases and greater knowledge of these molecules may bring about the development of strategies to inhibit their production, according to the authors.

Link to...

<p>Maximum likelihood phylogenetic tree based on ADAT2 and ADAT3 amino acid sequences. Source: Molecular Biology and Evolution</p>
10 Jan 2019

The study, published in the journal Molecular Biology and Evolution, has been headed by Lluís Ribas, at IRB Barcelona.

<p>Lluís Ribas, group leader at IRB Barcelona</p>
12 Feb 2017

In a short interview on RAC1 Radio, Lluís Ribas, ICREA researcher at IRB Barcelona, talks about the disturbing fall in the number of antibiotics available to treat infections—which has come about from “a vicious cycle between big pharma and regulatory agencies”. This decrease takes on great relevance given the increasing resistance of bacteria to antibiotics. 

“Public-funded research can provide the solution, by allowing the constant discovery of new antibiotics to replace those to which bacteria have become resistant,” explains Lluís Ribas.

<p>Eva Novoa's mother receives the Young Researchers Award in her name</p>
21 Jul 2016

Eva Novoa was one of the first students to complete a PhD in as part of the ”la Caixa”/IRB Barcelona International PhD Programme in Biomedicine. She was a PhD student at IRB Barcelona between 2008 and 2012. Six months ago, she moved to Sydney, Australia to join the Garvan Institute of Medical Research as a Senior Research Officer. She just received the Young Research Award from the Catalan Society for Biology.

13 Jun 2016

In an extensive interview in the Art and Science Channel Excodra, Lluís Ribas de Pouplana, ICREA researcher at IRB Barcelona, talks about many topics related to life, evolution, the genetic code and diseases.

In response to a question about how he thinks our species will evolve, Ribas says, "the genes that will exert greatest influence on our evolution are those involved in heat regulation because the inevitable phenomenon of global warming is on its way". The interview ends with advice for young researchers when they face failed experiments: "Many people can’t even get to do this experiment; what we do is great, we explore, we search for things and sometimes we find them."

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1 Jun 2016

Publico.es echoes a finding linked to the Rosetta space mission. The journalistic article describes the discovery of organic molecules on a comet and provides clues as to about how life may have arisen on Earth—one of the great enigmas of science. The journalist also mentions the discovery made by ICREA researcher at IRB Barcelona, Lluís Ribas de Pouplana, published in Science Advances, about the fundamental limit reached by the genetic code—the...

19 May 2016

"In love with the genetic code", the new video in the series Meet Our Scientists, presents the research performed by Lluís Ribas on the genetic code and protein synthesis, both of which are essential for life.

Ribas highlights the impact of the evolution of the enzyme ADAT, described in  the journal Cell in 2012. The appearance of ADAT was decisive for the separation of species into the three domains of life, and it could be of biomedical and biotech relevance.

3 May 2016

Broad international and national coverage of the study on the evolution of the genetic code published in Science Advances by Lluís Ribas, ICREA professor at IRB Barcelona. Sarah Emerson, editor of Motherboard, writes an article aimed at the general public on what caused the genetic code to stop evolving 3000 million years ago.

Read the article in Motherboard (USA)

Read the Article in Daily Mail (UK):...

<p>3D respresentation of a transfer RNA (tRNA). These molecules are crucial for the translation of genes into proteins and they are also the reason why the genetic code cannot exceed 20 amino acid. (Author: Pablo Dans, IRB Barcelona)</p>
2 May 2016

A study performed at IRB Barcelona offers an explanation as to why the genetic code, the dictionary used by organisms to translate genes into protein, stopped growing 3,000 million years ago.

The reason is attributed to the structure of transfer RNAs—the key molecules in the translation of genes into proteins.

The genetic code is limited to 20 amino acids—the building blocks of proteins—the maximum number that prevents systematic mutations, which are fatal for life.

The discovery could have applications in synthetic biology.

3 Nov 2015

Extensive report in El Mundo on the 10th anniversary of IRB Barcelona, including an interview with the director of the centre, Joan J. Guinovart. Sections devoted to highlighting the research performed by Ángel R. Nebreda and Lluís Ribas de Pouplana.

Go to El Mundo website (Spanish)