Molecular Modelling and Bioinformatics news

<p>When he was young, Enrique Marcos was attracted to science because he was curious and wanted to discover new things. "And, if on top of that it could be useful to society, even better.”</p>
6 Feb 2017

Postdoc Enrique Marcos (Barcelona 1982) is a chemist, a theoretical chemist to be exact. He has just published his first paper in Science, in which he explains how to computationally design the pocket-like cavities of proteins—essential areas that allow many proteins to perform their functions. And he has just been awarded a second Marie Skłodowska-Curie Action Fellowship.

 

<p>Examples of computationally designed proteins made of curved beta-sheets and helices forming cavities with different sizes and shapes (E.Marcos, IRB Barcelona-UW)</p>
16 Jan 2017

The local newspaper “La Mañana Diari de Ponent” has echoed a computational study of proteins performed by an international team led by the University of Washington (UW) in Seattle. The first author of the study, Enrique Marcos, is currently working in IRB Barcelona's Molecular Modelling and Bioinformatics Lab.

Published in Science, the study has deciphered key rules that govern how proteins form pocket-like structures that are essential for many key protein functions.

Other media mentions: 

Link to Sinc Agency

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<p>Examples of computationally designed proteins made of curved beta-sheets and helices forming cavities with different sizes and shapes (E.Marcos, IRB Barcelona-UW)</p>
13 Jan 2017

The international team achieved it by discovering the rules behind a type of protein structures that are essential for the interaction between proteins and small molecules

IRB Barcelona researcher, Enrique Marcos, is the first author of the study published today in Science

<p>Eadweard Muybridge's pictures of a galloping horse enabled detailed analysis of animals and humans in motion. Today's protein research is faced with a similar situation when trying to understand how proteins move. (L. Orellana)</p>
5 Sep 2016

Scientists at the Institute for Research in Biomedicine (IRB Barcelona) and the KTH Royal Institute of Technology in Stockholm develop a new method that predicts the way in which proteins move to exert their biological functions.

They have demonstrated that protein movement is governed by the general shape of these molecules, thereby providing new data on how proteins work—a key step for drug development.

<p>Eva Novoa's mother receives the Young Researchers Award in her name</p>
21 Jul 2016

Eva Novoa was one of the first students to complete a PhD in as part of the ”la Caixa”/IRB Barcelona International PhD Programme in Biomedicine. She was a PhD student at IRB Barcelona between 2008 and 2012. Six months ago, she moved to Sydney, Australia to join the Garvan Institute of Medical Research as a Senior Research Officer. She just received the Young Research Award from the Catalan Society for Biology.

<p>11 young scientists will learn about proteins, lab techniques and bioinformatics at IRB Barcelona</p>
21 Jul 2016

The Barcelona International Youth Science Challenge (BIYSC) is a singular programme run by the Catalunya-La Pedrera Foundation that seeks to bring together students with a passion for science and the best scientists in prestigious research centres in Catalonia.

IRB Barcelona participates in the BIYSC through the project “From DNA to protein related diseases”, which includes sessions about the different fields addressed at the institute.

13 Jul 2016

Several media have picked up on the launch of the new biotechnology company Nostrum BioDiscovery, a joint initiative between IRB Barcelona and the Barcelona Supercomputing Center-National Supercomputing Center (BSC-CNS). Modesto Orozco, group leader of the Molecular Modelling and Bioinformatics lab at IRB Barcelona, will chair the new spin-off, which aims to launch new drugs and biotech molecules developed using computational simulation.

<p>Víctor Guallar (left) and Modesto Orozco are the scientific leaders behind Nostrum BioDiscovery</p>
12 Jul 2016

Nostrum BioDiscovery has come about from the combined efforts of IRB Barcelona and the BSC-CNS—two research centres of excellence in Barcelona—with the participation of the University of Barcelona and ICREA and supported by the Botín Foundation’s technology transfer programme.

The company boasts cutting-edge bioinformatics technologies to speed up the development and lower the cost of designing drugs—which are becoming increasingly more complex and expensive—and to further precision medicine.

20 Dec 2015

Big Vang, the science section of La Vanguardia newspaper, publishes a questionnaire answered by Modesto Orozco.

14 Dec 2015

Fierce BiotechIT, a biotechnology-specialized website, has written an article on the new European project, led by Modesto Orozco, which will inject 3€ million euros into 3-D genomics.