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Research publications

Dietary palmitic acid promotes a prometastatic memory via Schwann cells
Pascual G, Domínguez D, Elosúa-Bayes M, Beckedorff F, Laudanna C, Bigas C, Douillet D, Greco C, Symeonidi A, Hernández I, Gil SR, Prats N, Bescós C, Shiekhattar R, Amit M, Heyn H, Shilatifard A, Benitah SA
599
485 -
490
2021
A gene–environment-induced epigenetic program initiates tumorigenesis
Alonso-Curbelo D, Ho YJ, Burdziak C, Maag JLV, Morris JP 4th, Chandwani R, Chen HA, Tsanov KM, Barriga FM, Luan L, Tasdemir N, Livshits G, Azizi E, Chun J, Wilkinson JE, Mazutis L, Leach SD, Koche R, Pe’er D, Lowe SW.
2021
Identification and selectivity profiling of small-molecule degraders via multi-omics approaches.
Scholes, N. S., Mayor-Ruiz, C. & Winter, G. E.
2021
Circadian Regulation of Adult Stem Cell Homeostasis and Aging
Benitah, SA; Welz, PS
26
6
817 -
831
2020
BIAFLOWS: A Collaborative Framework to Reproducibly Deploy and Benchmark Bioimage Analysis Workflows
Rubens, U; Mormont, R; Paavolainen, L; Backer, V; Pavie, B; Scholz, LA; Michiels, G; Maska, M; Unay, D; Ball, G; Hoyoux, R; Vandaele, R; Golani, O; Stanciu, SG; Sladoje, N; Paul-Gilloteaux, P; Maree, R; Tosi, S
1
3
100040 -
2020
Systematic analysis of alterations in the ubiquitin proteolysis system reveals its contribution to driver mutations in cancer
Martinez-Jimenez, F; Muinos, F; Lopez-Arribillaga, E; Lopez-Bigas, N; Gonzalez-Perez, A
1
1
122 -
+
2020
Pulmonary glycogen deficiency as a new potential cause of respiratory distress syndrome
Testoni G; Olmeda B; Duran J; López-Rodríguez E; Aguilera M; Hernández-Álvarez MI; Prats N; Pérez-Gil J; Guinovart JJ
29
21
3554 -
3565
2020
Assembly of the asymmetric human γ-tubulin ring complex by RUVBL1-RUVBL2 AAA ATPase
Zimmermann F; Serna M; Ezquerra A; Fernandez-Leiro R; Llorca O; Luders J
6
51
eabe0894 -
2020
In Vivo Reprogramming Ameliorates Aging Features in Dentate Gyrus Cells and Improves Memory in Mice
Rodríguez-Matellán A; Alcazar N; Hernández F; Serrano M; Ávila J
15
5
1056 -
1066
2020
The dialogue between the ubiquitin-proteasome system and autophagy: Implications in ageing
Sun-Wang JL; Ivanova S; Zorzano A
64
101203
101203 -
2020
Facilitated Diffusion of Proline across Membranes of Liposomes and Living Cells by a Calix[4]pyrrole Cavitand
Martínez-Crespo L; Sun-Wang JL; Sierra AF; Aragay G; Errasti-Murugarren E; Bartoccioni P; Palacín M; Ballester P
6
11
3054 -
3070
2020
A fraction of barrier-to-autointegration factor (BAF) associates with centromeres and controls mitosis progression
Torras-Llort, Monica; Medina-Giro, Sonia; Escudero-Ferruz, Paula; Lipinszki, Zoltan; Moreno-Moreno, Olga; Karman, Zoltan; Przewloka, Marcin R.; Azorin, Fernando;
3
1
454 -
2020
The evolution of relapse of adult T cell acute lymphoblastic leukemia
Sentis, Ines; Gonzalez, Santiago; Genesca, Eulalia; Garcia-Hernandez, Violeta; Muinos, Ferran; Gonzalez, Celia; Lopez-Arribillaga, Erika; Gonzalez, Jessica; Fernandez-Ibarrondo, Lierni; Mularoni, Loris; Espinosa, Lluis; Bellosillo, Beatriz; Ribera, Josep-Maria; Bigas, Anna; Gonzalez-Perez, Abel; Lopez-Bigas, Nuria;
21
1
284 -
2020
Global hyperactivation of enhancers stabilizes human and mouse naive pluripotency through inhibition of CDK8/19 Mediator kinases
Lynch CJ; Bernad R; Martínez-Val A; Shahbazi MN; Nóbrega-Pereira S; Calvo I; Blanco-Aparicio C; Tarantino C; Garreta E; Richart-Ginés L; Alcazar N; Graña-Castro O; Gómez-Lopez G; Aksoy I; Muñoz-Martín M; Martinez S; Ortega S; Prieto S; Simboeck E; Camasses A; Stephan-Otto Attolini C; Fernandez AF; Sierra MI; Fraga MF; Pastor J; Fisher D; Montserrat N; Savatier P; Muñoz J; Zernicka-Goetz M; Serrano M
22
10
1223 -
+
2020
Personalized cancer therapy prioritization based on driver alteration co-occurrence patterns
Mateo L; Duran-Frigola M; Gris-Oliver A; Palafox M; Scaltriti M; Razavi P; Chandarlapaty S; Arribas J; Bellet M; Serra V; Aloy P
12
1
78 -
2020
Discovery of EMRE in fungi resolves the true evolutionary history of the mitochondrial calcium uniporter
Pittis AA; Goh V; Cebrian-Serrano A; Wettmarshausen J; Perocchi F; Gabaldón T
11
1
4031 -
2020
A compendium of mutational cancer driver genes
Martínez-Jiménez F; Muiños F; Sentís I; Deu-Pons J; Reyes-Salazar I; Arnedo-Pac C; Mularoni L; Pich O; Bonet J; Kranas H; Gonzalez-Perez A; Lopez-Bigas N
20
10
555 -
572
2020
Manipulating the Mediator complex to induce naïve pluripotency
Lynch CJ; Bernad R; Calvo I; Serrano M
395
2
112215 -
2020
DNA mismatch repair promotes APOBEC3-mediated diffuse hypermutation in human cancers
Mas-Ponte D; Supek F
52
9
958 -
+
2020
Induction of lysosome membrane permeabilization as a therapeutic strategy to target pancreatic cancer stem cells
Cash TP; Alcalá S; Rico-Ferreira MDR; Hernández-Encinas E; García J; Albarrán MI; Valle S; Muñoz J; Martínez-González S; Blanco-Aparicio C; Pastor J; Serrano M; Sainz B
12
7
1790 -
25
2020
Probing the Kinetic and Thermodynamic Fingerprints of Anti-EGF Nanobodies by Surface Plasmon Resonance
Guardiola, Salvador; Varese, Monica; Taules, Marta; Diaz-Lobo, Mireia; Garcia, Jesus; Giralt, Ernest;
13
6
134 -
10
2020
Matching cell lines with cancer type and subtype of origin via mutational, epigenomic, and transcriptomic patterns
Salvadores, Marina; Fuster-Tormo, Francisco; Supek, Fran
6
27
eaba1862 -
2020
Self-Eating for Muscle Fitness: Autophagy in the Control of Energy Metabolism
Sebastián D; Zorzano A
54
2
268 -
281
2020
Optimal linker length for small molecule PROTACs that selectively target p38α and p38β for degradation
Donoghue C; Cubillos-Rojas M; Gutierrez-Prat N; Sanchez-Zarzalejo C; Verdaguer X; Riera A; Nebreda AR
201
112451
112451 -
2020
The NEUBIAS Gateway: A hub for bioimage analysis methods and materials
Miura K; Cimini BA; Nørrelykke SF; Louveaux M; Sladoje N; Paul-Gilloteaux P; Colombelli J
9
613 -
2020
Colibactin DNA-damage signature indicates mutational impact in colorectal cancer
Dziubańska-Kusibab PJ; Berger H; Battistini F; Bouwman BAM; Iftekhar A; Katainen R; Cajuso T; Crosetto N; Orozco M; Aaltonen LA; Meyer TF
26
7
1063 -
+
2020
Extending the small-molecule similarity principle to all levels of biology with the Chemical Checker
Duran-Frigola, M; Pauls, E; Guitart-Pla, O; Bertoni, M; Alcalde, V; Amat, D; Juan-Blanco, T; Aloy, P
38
9
1087 -
+
2020
Zonation of Ribosomal DNA Transcription Defines a Stem Cell Hierarchy in Colorectal Cancer
Morral C; Stanisavljevic J; Hernando-Momblona X; Mereu E; Álvarez-Varela A; Cortina C; Stork D; Slebe F; Turon G; Whissell G; Sevillano M; Merlos-Suárez A; Casanova-Martí À; Moutinho C; Lowe SW; Dow LE; Villanueva A; Sancho E; Heyn H; Batlle E
26
6
845 -
+
2020
LOBSTER: an environment to design bioimage analysis workflows for large and complex fluorescence microscopy data
Tosi S; Bardia L; Filgueira MJ; Calon A; Colombelli J
36
8
2634 -
2635
2020
A genetic analysis reveals novel histone residues required for transcriptional reprogramming upon stress
Viéitez C; Martínez-Cebrián G; Solé C; Böttcher R; Potel CM; Savitski MM; Onnebo S; Fabregat M; Shilatifard A; Posas F; de Nadal E
48
7
3455 -
3475
2020
The RNA binding protein CPEB2 regulates hormone sensing in mammary gland development and luminal breast cancer
Pascual, Rosa; Martin, Judit; Salvador, Fernando; Reina, Oscar; Chanes, Veronica; Millanes-Romero, Alba; Suner, Clara; Fernandez-Miranda, Gonzalo; Bartomeu, Anna; Huang, Yi-Shuian; Gomis, Roger R; Mendez, Raul
6
20
eaax3868 -
2020
Hog1 activation delays mitotic exit via phosphorylation of Net1
Tognetti S; Jiménez J; Viganò M; Duch A; Queralt E; de Nadal E; Posas F
117
16
8924 -
8933
2020
Imaging the Cell Morphological Response to 3D Topography and Curvature in Engineered Intestinal Tissues
Altay G; Tosi S; García-Díaz M; Martínez E
8
294
294 -
2020
A reference map of the human binary protein interactome
Luck K; Kim DK; Lambourne L; Spirohn K; Begg BE; Bian W; Brignall R; Cafarelli T; Campos-Laborie FJ; Charloteaux B; Choi D; Coté AG; Daley M; Deimling S; Desbuleux A; Dricot A; Gebbia M; Hardy MF; Kishore N; Knapp JJ; Kovács IA; Lemmens I; Mee MW; Mellor JC; Pollis C; Pons C; Richardson AD; Schlabach S; Teeking B; Yadav A; Babor M; Balcha D; Basha O; Bowman-Colin C; Chin SF; Choi SG; Colabella C; Coppin G; D’Amata C; De Ridder D; Luck K; Kim DK; Lambourne L; Spirohn K; Begg BE; Bian W; Brignall R; Cafarelli T; Campos-Laborie FJ; Charloteaux B; Choi D; Coté AG; Daley M; Deimling S; Desbuleux A; Dricot A; Gebbia M; Hardy MF; Kishore N; Knapp JJ; Kovács IA; Lemmens I; Mee MW; Mellor JC; Pollis C; Pons C; Richardson AD; Schlabach S; Teeking B; Yadav A; Babor M; Balcha D; Basha O; Bowman-Colin C; Chin SF; Choi SG; Colabella C; Coppin G; D’Amata C; De Ridder D; Luck K; Kim DK; Lambourne L; Spirohn K; Begg BE; Bian W; Brignall R; Cafarelli T
580
7803
402 -
+
2020
4D Genome Rewiring during Oncogene-Induced and Replicative Senescence
Sati S; Bonev B; Szabo Q; Jost D; Bensadoun P; Serra F; Loubiere V; Papadopoulos GL; Rivera-Mulia JC; Fritsch L; Bouret P; Castillo D; Gelpi JL; Orozco M; Vaillant C; Pellestor F; Bantignies F; Marti-Renom MA; Gilbert DM; Lemaitre JM; Cavalli G
78
3
522 -
+
2020
Emergence of chromatin hierarchical loops from protein disorder and nucleosome asymmetry
Sridhar A; Farr SE; Portella G; Schlick T; Orozco M; Collepardo-Guevara R
117
13
7216 -
7224
2020
Synthesis and Application of 3-Bromo-1,2,4,5-Tetrazine for Protein Labeling to Trigger Click-to-Release Biorthogonal Reactions
Ros E; Bellido M; Verdaguer X; De Pouplana LR; Riera A
31
3
933 -
938
2020
P-Stereogenic Amino-Phosphines as Chiral Ligands: From Privileged Intermediates to Asymmetric Catalysis
Cabré A; Riera A; Verdaguer X
53
3
676 -
689
2020
Catalytic Regioselective Isomerization of 2,2-Disubstituted Oxetanes to Homoallylic Alcohols
Cabré A; Rafael S; Sciortino G; Ujaque G; Verdaguer X; Lledós A; Riera A
59
19
7521 -
7527
2020
From whole-organ imaging to in-silico blood flow modeling: A new multi-scale network analysis for revisiting tissue functional anatomy
Kennel P; Dichamp J; Barreau C; Guissard C; Teyssedre L; Rouquette J; Colombelli J; Lorsignol A; Casteilla L; Plouraboué F
16
2
e1007322 -
2020
A multi-modal coarse grained model of DNA flexibility mappable to the atomistic level
Walther J; Dans PD; Balaceanu A; Hospital A; Bayarri G; Orozco M
48
5
e29 -
2020
Regulation of Anisotropic Tissue Growth by Two Orthogonal Signaling Centers
Barrio L; Milán M
52
5
659 -
+
2020
The mitochondrial tRNA conundrum
de Pouplana LR
21
7
361 -
361
2020
Gene gain and loss across the metazoan tree of life
Fernández R, Gabaldón T
4
4
524 -
533
2020
The embryonic linker histone dBigH1 alters the functional state of active chromatin
Climent-Cantó P, Carbonell A, Tatarski M, Reina O, Bujosa P, Font-Mateu J, Bernués J, Beato M, Azorín F
48
8
4147 -
4160
2020
Requirement for epithelial p38α in KRAS-driven lung tumor progression
Vitos-Faleato J, Real SM, Gutierrez-Prat N, Villanueva A, Llonch E, Drosten M, Barbacid M, Nebreda AR
117
5
2588 -
2596
2020
Characterization of Human Sperm Protamine Proteoforms through a Combination of Top-Down and Bottom-Up Mass Spectrometry Approaches
Soler-Ventura A; Gay M; Jodar M; Vilanova M; Castillo J; Arauz-Garofalo G; Villarreal L; Ballescà JL; Vilaseca M; Oliva R
19
1
221 -
237
2020
Dendritic cells in cancer immunology and immunotherapy
Wculek SK*, Cueto FJ*, Mujal AM, Melero I, Krummel MF, Sancho D#
(#) Corresponding author; (*) these authors contributed equally
20(1):7-24
2020