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Research publications

Self-Sensing Enzyme-Powered Micromotors Equipped with pH-Responsive DNA Nanoswitches
Patino T; Porchetta A; Jannasch A; Lladó A; Stumpp T; Schäffer E; Ricci F; Sánchez S
19
6
3440 -
3447
2019
Modeling, Simulations, and Bioinformatics at the Service of RNA Structure
Dans P; Gallego D; Balaceanu A; Darré L; Gómez H; Orozco M
5
1
51 -
73
2019
Fibroblasts Mobilize Tumor Cell Glycogen to Promote Proliferation and Metastasis
Curtis M; Kenny HA; Ashcroft B; Mukherjee A; Johnson A; Zhang Y; Helou Y; Batlle R; Liu X; Gutierrez N; Gao X; Yamada SD; Lastra R; Montag A; Ahsan N; Locasale JW; Salomon AR; Nebreda AR; Lengyel E
29
1
141 -
155.e9
2019
Rapid reversible changes in compartments and local chromatin organization revealed by hyperosmotic shock
Amat R; Böttcher R; Le Dily F; Vidal E; Quilez J; Cuartero Y; Beato M; De Nadal E; Posas F
29
1
18 -
28
2019
Encircling the regions of the pharmacogenomic landscape that determine drug response
Fernandez-Torras, Adria; Duran-Frigola, Miquel; Aloy, Patrick
11
17
17 -
2019
Regulation of death receptor signaling by the autophagy protein TP53INP2
Ivanova, Saska; Polajnar, Mira; Jesus Narbona-Perez, Alvaro; Isabel Hernandez-Alvarez, Maria; Frager, Petra; Slobodnyuk, Konstantin; Plana, Natalia; Nebreda, Angel R; Palacin, Manuel; Gomis, Roger R; Behrends, Christian; Zorzano, Antonio
38
10
-
2019
Plasticity of the Cullin-RING Ligase Repertoire Shapes Sensitivity to Ligand-Induced Protein Degradation
Mayor-Ruiz, C.1,*, Jaeger, M.G*, Bauer, S., Brand, M., Sin, C., Hanzl, A., Mueller, A.C., Menche, J., and Winter, G.E.1
1 co-corresponding; *Co-first authors
75
849 -
858
2019
A Species-Wide Inventory of NLR Genes and Alleles in Arabidopsis thaliana
Anna-Lena Van de Weyer, Freddy Monteiro, Oliver J Furzer, Marc T Nishimura, Volkan Cevik, Kamil Witek, Jonathan D G Jones, Jeffery L Dangl, Detlef Weigel, Felix Bemm
5
178
1260 -
1272.e14
2019
TIR domains of plant immune receptors are NAD +-cleaving enzymes that promote cell death
Li Wan, Kow Essuman, Ryan G Anderson, Yo Sasaki, Freddy Monteiro, Eui-Hwan Chung, Erin Osborne Nishimura, Aaron DiAntonio, Jeffrey Milbrandt, Jeffery L Dangl, Marc T Nishimura
6455
365
799 -
803
2019
Identification and characterization of cancer vulnerabilities via targeted protein degradation
Mayor-Ruiz, C., and Winter, G.E
31
81 -
90
2019
Plasticity of the Cullin-RING Ligase Repertoire Shapes Sensitivity to Ligand-Induced Protein Degradation
Mayor-Ruiz, C (#) (1), Jaeger, M.G (#), Bauer, S., Brand, M., Sin, C., Hanzl, A., Mueller, A.C., Menche, J., and Winter, G.E (1). (1) Co-corresponding authors; (# Equal contribution)
75
849 -
858
2019
Mitochondrial DNA and TLR9 drive muscle inflammation upon Opa1 deficiency
Rodriguez-Nuevo, Aida; Diaz-Ramos, Angels; Noguera, Eduard; Diaz-Saez, Francisco; Duran, Xavier; Pablo Munoz, Juan; Romero, Montserrat; Plana, Natalia; Sebastian, David; Tezze, Caterina; Romanello, Vanina; Ribas, Francesc; Seco, Jordi; Planet, Evarist; Doctrow, Susan R; Gonzalez, Javier; Borras, Miquel; Liesa, Marc; Palacin, Manuel; Vendrell, Joan; Villarroya, Francesc; Sandri, Marco; Shirihai, Orian; Zorzano, Antonio
37
10
-
2018
Citizen science charts two major "stomatotypes" in the oral microbiome of adolescents and reveals links with habits and drinking water composition
Willis JR, González-Torres P, Pittis AA, Bejarano LA, Cozzuto L, Andreu-Somavilla N, Alloza-Trabado M, Valentín A, Ksiezopolska E, Company C, Onywera H, Montfort M, Hermoso A, Iraola-Guzmán S, Saus E, Labeeuw A, Carolis C, Hecht J, Ponomarenko J, Gabaldón T
6
1
218 -
218
2018
Toward quantitative three-dimensional microvascular networks segmentation with multiview light-sheet fluorescence microscopy
Kennel, Pol; Teyssedre, Lise; Colombelli, Julien; Plouraboue, Franck
23
8
1 -
14
2018
3D imaging of cleared human skin biopsies using light-sheet microscopy: A new way to visualize in-depth skin structure
Abadie, S; Jardet, C; Colombelli, J; Chaput, B; David, A; Grolleau, J -L; Bedos, P; Lobjois, V; Descargues, P; Rouquette, J
24
2
294 -
303
2018
Senescence promotes invivo reprogramming through p16(INK4a) and IL-6
Mosteiro, Lluc; Pantoja, Cristina; de Martino, Alba; Serrano, Manuel
17
2
-
2018
Targeting senescence
Serrano, Manuel; Barzilai, Nir
24
8
1092 -
1094
2018
AAVvector-mediated in vivo reprogramming into pluripotency
Senis, Elena; Mosteiro, Lluc; Wilkening, Stefan; Wiedtke, Ellen; Nowrouzi, Ali; Afzal, Saira; Fronza, Raffaele; Landerer, Henrik; Abad, Maria; Niopek, Dominik; Schmidt, Manfred; Serrano, Manuel; Grimm, Dirk
9
2651
2651 -
2018
Direct Evidence of the Presence of Cross-Linked A beta Dimers in the Brains of Alzheimer's Disease Patients
Vazquez de la Torre, Aurelio; Gay, Marina; Vilaprinyo-Pascual, Silvia; Mazzucato, Roberta; Serra-Batiste, Montserrat; Vilaseca, Marta; Carulla, Natalia
90
7
4552 -
4560
2018
Morphogenetic movements affect local tissue organisation during embryonic Drosophila morphogenesis
Letizia, Annalisa; Tosi, Sebastien; Llimargas, Marta
97
4
243 -
256
2018
Identity Noise and Adipogenic Traits Characterize Dermal Fibroblast Aging
Claudia Salzer, Marion; Lafzi, Atefeh; Berenguer-Llergo, Antoni; Youssif, Catrin; Castellanos, Andres; Solanas, Guiomar; Oliveira Peixoto, Francisca; Stephan-Otto Attolini, Camille; Prats, Neus; Aguilera, Monica; Martin-Caballero, Juan; Heyn, Holger; Aznar Benitah, Salvador
175
6
1575 -
+
2018
Direct Asymmetric Hydrogenation of N-Methyl and N-Alkyl Imines with an Ir(III)H Catalyst
Salomó E; Gallen A; Sciortino G; Ujaque G; Grabulosa A; Lledós A; Riera A; Verdaguer X
140
49
16967 -
16970
2018
Chromosomal Instability Induces Cellular Invasion in Epithelial Tissues
Benhra N; Barrio L; Muzzopappa M; Milán M
47
2
161 -
174.e4
2018
Somatic and Germline Mutation Periodicity Follow the Orientation of the DNA Minor Groove around Nucleosomes
Pich O; Muiños F; Sabarinathan R; Reyes-Salazar I; Gonzalez-Perez A; Lopez-Bigas N
175
4
1074 -
1087.e18
2018
TGIF1 homeodomain interacts with Smad MH1 domain and represses TGF- signaling
Guca E; Suñol D; Ruiz L; Konkol A; Cordero J; Torner C; Aragon E; Martin-Malpartida P; Riera A; Macias M
46
17
9220 -
9235
2018
Cancer Mutations of the Tumor Suppressor SPOP Disrupt the Formation of Active, Phase-Separated Compartments
Bouchard J; Otero J; Scott D; Szulc E; Martin E; Sabri N; Granata D; Marzahn M; Lindorff-Larsen K; Salvatella X; Schulman B; Mittag T
72
1
19 -
36.e8
2018
Centrobin is essential for c-tubule assembly and flagellum development in drosophila melanogaster spermatogenesis
Reina J; Gottardo M; Riparbelli M; Llamazares S; Callaini G; Gonzalez C
217
7
2365 -
2372
2018
The evolutionary signal in metagenome phyletic profiles predicts many gene functions
Vidulin V; Šmuc T; Džeroski S; Supek F
6
1
129 -
2018
Myeloid p38α signaling promotes intestinal IGF-1 production and inflammation-associated tumorigenesis
Youssif C; Cubillos-Rojas M; Comalada M; Llonch E; Perna C; Djouder N; Nebreda A
10
7
-
2018
TP53INP2 regulates adiposity by activating β-catenin through autophagy-dependent sequestration of GSK3β
Romero M; Sabaté-Pérez A; Francis VA; Castrillón-Rodriguez I; Díaz-Ramos Á; Sánchez-Feutrie M; Durán X; Palacín M; Moreno-Navarrete JM; Gustafson B; Hammarstedt A; Fernández-Real JM; Vendrell J; Smith U; Zorzano A
20
4
443 -
454
2018
Differential roles of the Drosophila EMT-inducing transcription factors Snail and Serpent in driving primary tumour growth
Campbell K; Lebreton G; Franch-Marro X; Casanova J
14
2
e1007167 -
2018
Identification of New Activators of Mitochondrial Fusion Reveals a Link between Mitochondrial Morphology and Pyrimidine Metabolism
Miret-Casals L; Sebastián D; Brea J; Rico-Leo E; Palacín M; Fernández-Salguero P; Loza M; Albericio F; Zorzano A
25
3
268 -
278.e4
2018
Multiple signaling kinases target Mrc1 to prevent genomic instability triggered by transcription-replication conflicts
Duch A; Canal B; Barroso S; García-Rubio M; Seisenbacher G; Aguilera A; De Nadal E; Posas F
9
1
379 -
2018
Regulation of Androgen Receptor Activity by Transient Interactions of Its Transactivation Domain with General Transcription Regulators
De Mol E; Szulc E; Di Sanza C; Martínez-Cristóbal P; Bertoncini C; Fenwick R; Frigolé-Vivas M; Masín M; Hunter I; Buzón V; Brun-Heath I; García J; De Fabritiis G; Estébanez-Perpiñá E; McEwan I; Nebreda Á; Salvatella X
26
1
145 -
152.e3
2018
Adherens Junction Length during Tissue Contraction Is Controlled by the Mechanosensitive Activity of Actomyosin and Junctional Recycling
Sumi, Angughali; Hayes, Peran; D'Angelo, Arturo; Colombelli, Julien; Salbreux, Guillaume; Dierkes, Kai; Solon, Jerome
47
4
453 -
+
2018
Iridium-Catalyzed Isomerization of N-Sulfonyl Aziridines to Allyl Amines
Cabré A, Sciortino G, Ujaque G, Verdaguer X, Lledós A, Riera A
20
18
5747 -
5751
2018
A versatile drug delivery system targeting senescent cells
Muñoz-Espín D; Rovira M; Galiana I; Giménez C; Lozano-Torres B; Paez-Ribes M; Llanos S; Chaib S; Muñoz-Martín M; Ucero AC; Garaulet G; Mulero F; Dann SG; VanArsdale T; Shields DJ; Bernardos A; Murguía JR; Martínez-Máñez R; Serrano M
10
9
-
2018
Total Synthesis of ( R)-Sarkomycin Methyl Ester via Regioselective Intermolecular Pauson-Khand Reaction and Iridium-Catalyzed Asymmetric Isomerization.
Cabré A, Khaizourane H, Garçon M, Verdaguer X, Riera A
20
13
3953 -
3957
2018
Autism-like phenotype and risk gene mRNA deadenylation by CPEB4 mis-splicing
Parras A; Anta H; Santos-Galindo M; Swarup V; Elorza A; Nieto-González J; Picó S; Hernández I; Díaz-Hernández J; Belloc E; Rodolosse A; Parikshak N; Peñagarikano O; Fernández-Chacón R; Irimia M; Navarro P; Geschwind D; Méndez R; Lucas J
560
7719
441 -
446
2018
TGFβ drives immune evasion in genetically reconstituted colon cancer metastasis.
Tauriello DVF, Palomo-Ponce S, Stork D, Berenguer-Llergo A, Badia-Ramentol J, Iglesias M, Sevillano M, Ibiza S, Cañellas A, Hernando-Momblona X, Byrom D, Matarin JA, Calon A, Rivas EI, Nebreda AR, Riera A, Attolini CS, Batlle E
554
7693
538 -
543
2018
NEK7 regulates dendrite morphogenesis in neurons via Eg5-dependent microtubule stabilization
Freixo, Francisco; Delgado, Paula Martinez; Manso, Yasmina; Sanchez-Huertas, Carlos; Lacasa, Cristina; Soriano, Eduardo; Roig, Joan; Lueders, Jens
9
2330
2330 -
2018
Targeting p38α Increases DNA Damage, Chromosome Instability, and the Anti-tumoral Response to Taxanes in Breast Cancer Cells
Cánovas B; Igea A; Sartori A; Gomis R; Paull T; Isoda M; Pérez-Montoyo H; Serra V; González-Suárez E; Stracker T; Nebreda A
33
6
1094 -
1110.e8
2018
The RNA Polymerase II Factor RPAP1 Is Critical for Mediator-Driven Transcription and Cell Identity
Lynch, Cian J; Bernad, Raquel; Calvo, Isabel; Nobrega-Pereira, Sandrina; Ruiz, Sergio; Ibarz, Nuria; Martinez-Val, Ana; Grana-Castro, Osvaldo; Gomez-Lopez, Gonzalo; Andres-Leon, Eduardo; Angarica, Vladimir Espinosa; del Sol, Antonio; Ortega, Sagrario; Fernandez-Capetillo, Oscar; Rojo, Enrique; Munoz, Javier; Serrano, Manuel
22
2
396 -
410
2018
Cooperation of Antiporter LAT2/CD98hc with Uniporter TAT1 for Renal Reabsorption of Neutral Amino Acids.
Vilches C, Boiadjieva-Knöpfel E, Bodoy S, Camargo S, López de Heredia M, Prat E, Ormazabal A, Artuch R, Zorzano A, Verrey F, Nunes V, Palacín M
29
6
1624 -
1635
2018
Cancer Genome Interpreter annotates the biological and clinical relevance of tumor alterations
Tamborero D; Rubio-Perez C; Deu-Pons J; Schroeder M; Vivancos A; Rovira A; Tusquets I; Albanell J; Rodon J; Tabernero J; de Torres C; Dienstmann R; Gonzalez-Perez A; Lopez-Bigas N
10
1
467 -
2018
Mutations in L-type amino acid transporter-2 support SLC7A8 as a novel gene involved in Age-Related Hearing Loss.
Espino Guarch M, Font-Llitjós M, Murillo-Cuesta S, Errasti-Murugarren E, Celaya AM, Girotto G, Vuckovic D, Mezzavilla M, Vilches C, Bodoy S, Sahún I, González L, Prat E, Zorzano A, Dierssen M, Varela-Nieto I, Gasparini P, Palacín M, Nunes V
7
e31511
-
2018
MSK1 regulates luminal cell differentiation and metastatic dormancy in ER+breast cancer
Gawrzak S; Rinaldi L; Gregorio S; Arenas EJ; Salvador F; Urosevic J; Figueras-Puig C; Rojo F; Del Barco Barrantes I; Cejalvo JM; Palafox M; Guiu M; Berenguer-Llergo A; Symeonidi A; Bellmunt A; Kalafatovic D; Arnal-Estapé A; Fernández E; Müllauer B; Groeneveld R; Slobodnyuk K; Stephan-Otto Attolini C; Saura C; Arribas J; Cortes J; Rovira A; Muñoz M; Lluch A; Serra V; Albanell J; Prat A; Nebreda AR; Benitah SA; Gomis RR
20
2
211 -
221
2018
ERF deletion rescues RAS deficiency in mouse ES cells
Mayor-Ruiz C., Olbrich T., Drosten M., Lecona E., Vega-Sendino M., Ortega S., Dominguez O., Barbacid M., Ruiz S. & Fernandez-Capetillo O
32
568 -
576
2018