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Research

At the forefront of biomedicine

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Research publications

Neurodegeneration and functional impairments associated with glycogen synthase accumulation in a mouse model of Lafora disease
Valles-Ortega J; Duran J; Garcia-Rocha M; Bosch C; Saez I; Pujadas L; Serafin A; Cañas X; Soriano E; Delgado-García J; Gruart A; Guinovart J
3
11
667 -
681
2011
The F box protein partner of paired regulates stability of drosophila centromeric histone H3, CenH3 CID
Moreno-Moreno O; Medina-Giró S; Torras-Llort M; Azorín F
21
17
1488 -
1493
2011
Cleavage of E-cadherin by ADAM10 mediates epithelial cell sorting downstream of EphB signalling
Solanas G; Cortina C; Sevillano M; Batlle E
13
9
1100 -
1109
2011
A smad action turnover switch operated by WW domain readers of a phosphoserine code
Aragón E; Goerner N; Zaromytidou A; Xi Q; Escobedo A; Massagué J; Macias M
25
12
1275 -
1288
2011
Drosophila neuroblasts retain the daughter centrosome
Januschke J; Llamazares S; Reina J; Gonzalez C
2
1
243 -
2011
Distributed biological computation with multicellular engineered networks
Regot S; MacIa J; Conde N; Furukawa K; Kjellén J; Peeters T; Hohmann S; De Nadal E; Posas F; Solé R
469
7329
207 -
211
2011
The structure of a transcription activation subcomplex reveals how sigma(70) is recruited to PhoB promoters
Blanco, Alexandre G; Canals, Albert; Bernues, Jordi; Sola, Maria; Coll, Miquel
30
18
3776 -
3785
2011
The Intestinal Stem Cell Signature Identifies Colorectal Cancer Stem Cells and Predicts Disease Relapse
Merlos-Suarez, Anna; Barriga, Francisco M; Jung, Peter; Iglesias, Mar; Virtudes Cespedes, Maria; Rossell, David; Sevillano, Marta; Hernando-Momblona, Xavier; da Silva-Diz, Victoria; Munoz, Purificacion; Clevers, Hans; Sancho, Elena; Mangues, Ramon; Batlle, Eduard
8
5
511 -
524
2011
DDOR is an EcR coactivator that forms a feed-forward loop connecting insulin and ecdysone signaling
Francis V; Zorzano A; Teleman A
20
20
1799 -
1808
2010
Subjects with early-onset type 2 diabetes show defective activation of the skeletal muscle PGC-1α/mitofusin-2 regulatory pathway in response to physical activity
Her?andez-Alvarez M; Thabit H; Burns N; Shah S; Brema I; Hatunic M; Finucane F; Liesa M; Chiellini C; Naon D; Zorzano A; Nolan J
33
3
645 -
651
2010
Ectopic expression of germline genes drives malignant brain tumor growth in Drosophila
Janic A; Mendizabal L; Llamazares S; Rossell D; Gonzalez C
330
6012
1824 -
1827
2010
A dp53-dependent mechanism involved in coordinating tissue growth in Drosophila
Mesquita D; Dekanty A; Milán M
8
12
e1000566 -
2010
Hepatic overexpression of a constitutively active form of liver glycogen synthase improves glucose homeostasis
Ros S; Zafra D; Valles-Ortega J; García-Rocha M; Forrow S; Domínguez J; Calbó J; Guinovart J
285
48
37170 -
37177
2010
Human mitochondrial mTERF wraps around DNA through a left-handed superhelical tandem repeat
Jiménez-Menéndez N; Fernández-Millán P; Rubio-Cosials A; Arnan C; Montoya J; Jacobs H; Bernadó P; Coll M; Usón I; Solá M
17
7
891 -
893
2010
The miRNA machinery targets Mei-P26 and regulates Myc protein levels in the Drosophila wing
Herranz H; Hong X; Pérez L; Ferreira A; Olivieri D; Cohen S; Milán M
29
10
1688 -
1698
2010
Mitotic cell-cycle progression is regulated by CPEB1 and CPEB4-dependent translational control
Novoa I; Gallego J; Ferreira P; Mendez R
12
5
447 -
U82
2010
A Role of Receptor Notch in Ligand cis-Inhibition in Drosophila
Becam I; Fiuza UM; Arias AM; Milán M
20
6
554 -
560
2010
Chimeric tRNAs as tools to induce proteome damage and identify components of stress responses
Geslain R, Cubells L, Bori-Sanz T, Alvarez-Medina R, Rossell D, Martí E, Ribas de Pouplana L
38
5
e30 -
e30
2010
Structure and inhibition of herpesvirus DNA packaging terminase nuclease domain
Nadal M, Mas PJ, Blanco AG, Arnan C, Solà M, Hart DJ, Coll M
107
37
16078-83 -
16083
2010
Self-killing of melanoma cells by cytosolic delivery of dsRNA: Wiring innate immunity for a coordinated mobilization of endosomes, autophagosomes and the apoptotic machinery in tumor cells
Alonso-Curbelo D, Soengas MS
2010
The Ink4/Arf locus is a barrier for iPS cell reprogramming
Li, Han; Collado, Manuel; Villasante, Aranzazu; Strati, Katerina; Ortega, Sagrario; Canamero, Marta; Blasco, Maria A; Serrano, Manuel
460
7259
1136 -
U101
2009
Focus on the centre: The role of chromatin on the regulation of centromere identity and function
Torras-Llort M; Moreno-Moreno O; Azorín F
28
16
2337 -
2348
2009
Pulsed Forces Timed by a Ratchet-like Mechanism Drive Directed Tissue Movement during Dorsal Closure
Solon, Jerome; Kaya-Copur, Aynur; Colombelli, Julien; Brunner, Damian
137
7
1331 -
1342
2009
Targeted activation of innate immunity for therapeutic induction of autophagy and apoptosis in melanoma cells
Tormo D, Checińska A, Alonso-Curbelo D, Pérez-Guijarro E, Cañón E, Riveiro-Falkenbach E, Calvo TG, Larribere L, et al, [corr. author] Soengas MS.
2009
An Operational RNA Code for Faithful Assignment of AUG Triplets to Methionine
Jones T; Brown C; Geslain R; Alexander R; de Pouplana L
29
3
401 -
407
2008
Drosophila HP1c isoform interacts with the zinc-finger proteins WOC and Relative-of-WOC to regulate gene expression
Font-Burgada J; Rossell D; Auer H; Azorín F
22
21
3007 -
3023
2008
Spindle-localized CPE-mediated translation controls meiotic chromosome segregation
Eliscovich C; Peset I; Vernos I; Méndez R
10
7
858 -
865
2008
A deadenylation negative feedback mechanism governs meiotic metaphase arrest
Belloc E; Méndez R
452
7190
1017 -
U11
2008
The fission yeast homologue of CENP-B, Abp1, regulates directionality of mating-type switching
Aguilar-Arnal L; Marsellach F; Azorín F
27
7
1029 -
1038
2008
A Combinatorial Code for CPE-Mediated Translational Control
Piqué M; López J; Foissac S; Guigó R; Méndez R
132
3
434 -
448
2008
A Wingless and Notch double-repression mechanism regulates G1-S transition in the Drosophila wing.
Herranz H, Pérez L, Martín FA, Milán M
27
11
1633-1645 -
1645
2008
Mechanism suppressing glycogen synthesis in neurons and its demise in progressive myoclonus epilepsy
Vilchez D; Ros S; Cifuentes D; Pujadas L; Vallès J; García-Fojeda B; Criado-García O; Fernández-Sánchez E; Medrão-Fernández I; Domínguez J; García-Rocha M; Soriano E; Rodríguez De Córdoba S; Guinovart JJ
10
11
1407 -
1413
2007
Induction of tumor growth by altered stem-cell asymmetric division in Drosophila melanogaster
Caussinus E; Gonzalez C
37
10
1125 -
1129
2005
Hog1 mediates cell-cycle arrest in G1 phase by the dual targeting of Sic1
Escote, X; Zapater, M; Clotet, J; Posas, F
6
10
997 -
+
2004
The MAPK Hog1 recruits Rpd3 histone deacetylase to activate osmoresponsive genes
De Nadal E; Zapater M; Alepuz P; Sumoy L; Mas G; Posas F
427
6972
370 -
374
2004