Several media outlets have reported on a study led Angel Nebreda, ICREA researcher at the Institute for Research in Biomedicine (IRB Barcelona). In this work, his team has observed that p38 inhibition causes a dramatic reduction in the growth and aggressiveness of lung tumours.
Link to: La Vanguardia
Link to: ABC
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Ángel Nebreda’s team has published a study in the journal PNAS reporting the involvement of the protein p38 in the progression of lung cancer.
The work shows that patients with low levels of this protein have a better prognosis.
One of the biggest challenges faced by biomedicine is the development of more selective and efficient cancer treatments.
RAC1, La Sexta and the newspapers La Vanguardia and ABC, among other media, have echoed on news of a study done by researchers of IRB Barcelona that has demonstrated that the p38 protein regulates the formation of new blood vessels in tumours. A greater understanding of how the development of new blood vessels is regulated may help to improve chemotherapy treatments for cancer.
Link to RAC1
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Ángel R. Nebreda’s team (IRB Barcelona) publishes a study in the journal Nature Communications addressing the role of the p38 protein in angiogenesis—the formation of new blood vessels—a critical process that fuels tumour cells and allows them to grow and eventually develop metastases.
A greater understanding of how new blood vessel formation is regulated could help to improve chemotherapy treatments for cancer, as well as to develop more efficient angiogenic therapies for other diseases.
Many treatments against cancer, such as TRAIL, aim to trigger a type of cell death known as apoptosis.
A team at IRB Barcelona, headed by Antonio Zorzano, has demonstrated that the protein TP53INP2 induces apoptosis in chemotherapy treatments.
La Opinión de Zamora has published an article summarising the days of oncological research organised by the United Association against Cancer Toro and its Alfoz (AUCCTA) and in which Angel R. Nebreda, ICREA researcher at the Institute for Research in Biomedicine (IRB Barcelona) participated. During his talk, Nebreda commented: "We have come a long way but we still have a lot to do.But think about what we have achieved in the last 30 years, we know a lot more about how cancer develops and we have many more diagnostic methods, we know that there are hereditary cancers, that are genetic, and that they can be prevented by removing breasts and ovaries. We know that lung cancer is directly...
Tot Barcelona, e-notícies and El Plural have published an interview with Begoña Cánovas, a postdoctoral researcher at IRB Barcelona, who, thanks to a grant from "la Caixa", has been part of the team of researchers that detected the protein that fuels the survival of a type of breast cancer. "The day they gave me the first fellowship, I couldn’t believe it. I felt great and my parents jumped for joy when they found out. When you see all the applications, you feel like it's a lottery and you think you have no chance of winning, but it's worth trying, "said Cánovas.
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The newspaper "La Opinion" interviewed Angel R. Nebreda, ICREA researcher at IRB Barcelona, who will be participating in a conference on breast cancer on October 18 within the Health Forums of La Opinion and El Correo de Zamora. In this conference, he will be talking about his work in the lab on tumour formation and his efforts to unravel the mechanisms responsible for the transformation of normal tissue to a tumour.
Link to La Opinión
The projects address breast, lung, colon, prostate and melanoma cancer.
The newspaper “La Opinión de Zamora” has published an article devoted to breast cancer, one of the tumours most widely diagnosed in women in Spain and one of the most lethal.
The newspaper is organising a conference on breast cancer on 18 October, to which Angel R. Nebreda, ICREA researcher at IRBBarcelona, has been invited. The scientist will explain the breakthroughs achieved in basic research that can contribute to personalised treatments. Recently, Nebreda’s lab published a paper in the journal Cancer Cell reporting on a mechanism that prevents tumour...