Stem Cells and Cancer news

<p>Gloria Pascual, Research Associate at IRB Barcelona. Picture: Fundación Pfizer</p>
19 Feb 2019

The Pfizer Foundation has awarded the IRB Barcelona scientist a prize within the “Basic Research” category.

Gloria Pascual, a member of the Stem Cells and Cancer lab, will receive €10,000 to continue her research

<p>Biennal Ciutat i Ciència</p>
16 Jan 2019

From 7 to 11 February, the general public will have the opportunity to participate in activities related to ageing, nanoscience and climate change, among others.

IRB Barcelona will be taking part in the Biennal event through three initiatives that target the public.

<p>Quo magazine cover</p>
31 Dec 2018

Quo magazine has published a report on the aesthetic treatments that people use to stay young. They mention, for example, Botox, red light masks, breast prostheses, among others. In the article, they include the statements of experts in the field of health and research and also mention the study performed by IRB Barcelona and CNAG-CRG on the aging of the skin caused by the loss of identity and function of the main cells of the dermis.

 

<p>A invasive front of highly aggressive tumour cells (in green). Confocal microscopy image. Alexandra Avgustinova, IRB Barcelona.</p>
28 Dec 2018

The web Hidden Nature has published an article about the 10 investigations that they considered to be the most important ones published in 2018. One of them refers to epigenetic therapies and mentions research research that supports and rejects them. In this regard, they mention the study led by Salvador Aznar Benitah at IRB Barcelona and published in Nature Cell Biology. The study in question concludes that care must be taken with drugs that inhibit epigenetic factors as they could cause the appearance of aggressive tumours.

Link to Hidden Nature

<p>A invasive front of highly aggressive tumour cells (in green). Confocal microscopy image. Alexandra Avgustinova, IRB Barcelona.</p>
20 Dec 2018

The journal Biocentury Innovations has published an article on the study led by IRB Barcelona researchers Salvador Aznar Benitah and Fran Supek and first-authored by postdoctoral researcher Alexandra Avgustinova. The study has shown that increasing chromatin accessibility in cancer promotes tumour aggressiveness and does not reduce tumour mutation burden, as previously believed. The article refers to one of the main conclusions of the study, namely the need to evaluate the long-term effects of chromatin modifiers in tumour models before taking them into the clinic.

 

<p>Alexandra Avgustinova, postdoctoral fellow at IRB Barcelona</p>
18 Dec 2018

Medical Research has interviewed Alexandra Avgustinova, postdoctoral fellow at IRB Barcelona, about a study published as first author in the journal Nature Cell Biology. In the interview she explains that they have demonstrated that the common belief that chromatin opening is one of the determinants of a number of DNA mutations is incorrect. This discovery, says Avgustinova, is important for the fields of oncology and cancer genomics. “We were surprised to see that this observation was interpreted as a causal association, as it was, to a great extent, based on correlative studies without any experimental support. We decided to experimentally test for the first time whether the alteration...

<p>Image: SINC</p>
28 Nov 2018

SINC, El Público, Catalunya Vanguardista and the newspaper Heraldo de Aragón, have published an article about the process and conditions that triggers cancer according to a study published in the journal Science that raises new theories about aging. The article includes the opinion of Salvador Aznar Benitah, ICREA researcher at IRB Barcelona, about the study: "it is a very well done piece of work, with a very sophisticated analysis. We tend to think that the tumour tissue has mutations and the healthy one does not, but that is not the case. Healthy tissue can accumulate changes and appear normal, but it is no longer a normal tissue. "

Link to...

<p>Image: IRB Barcelona</p>
21 Nov 2018

La Vanguardia, Cope, Revista Genética, among other media, have each published an article about the latest study led by ICREA researchers Salvador Aznar Benitah and Fran Supek. The study warns that special care should be taken regarding epigenetic therapies since although their anti-tumour effect may be beneficial initially, they can trigger the development of more aggressive tumours later on.

Link to La Vanguardia

Link to...

<p>A invasive front of highly aggressive tumour cells (in green). Confocal microscopy image. Alexandra Avgustinova, IRB Barcelona.</p>
19 Nov 2018

A team headed by ICREA researchers Salvador Aznar Benitah and Fran Supek concludes that care should be taken with drugs that inhibit epigenetic factors.

Published in Nature Cell Biology, the study is a collaboration between a biomedical lab and a computational lab at IRB Barcelona.

<p>Salvador Aznar Benitah, head of the IRB Barcelona group "Stem Cells and Cancer". (Photo: Battista-Minocri, IRB)</p>
12 Nov 2018

Catalunya Ràdio interviewed Salvador Aznar Benitah, head of the Stem Cells and Cancer Lab at IRB Barcelona, and co-author of a recent study indicating that skin cells lose their identity over time and starts behaving like fat cells and thus do not exert their protective action.

Link to Catalunya Ràdio