Stem cells and cancer news

<p>DNA damage accumulation (in green) in old mice skin (Guiomar Solanas and Francisca Peixoto, IRB Barcelona)</p>
16 Aug 2017

Several media, including Catalonia's public television channel TV3, have echoed research on stem cell circadian rhythm headed by Salvador Aznar Benitah at IRB Barcelona and done in collaboration with the Pompeu Fabra University (UPF) and the University of California, Irvine (US).

Published in Cell, the two studies reject the scientific dogma associating ageing with the loss of stem cell circadian rhythm and explain why a calorie restriction diet slows down ageing.

Link to TV3 (Interview with PhD student Francisca Oliveira Peixoto, co-first author of the studies together...

<p>Image representing the effects of the circadian clock in ageing (Author: Iris Joval Granollers)</p>
10 Aug 2017

Stem cell functions continue to be governed by day and night cycles (circadian rhythms) during ageing, but their rhythms become devoted to tissue repair and not to the maintenance of tissue tone.

The two studies published in Cell and headed by Salvador Aznar Benitah at IRB Barcelona reject the scientific dogma associating ageing with the loss of stem cell circadian rhythm.

A low-calorie diet delays alterations in the rhythmic functions of stem cells and slows down ageing.

<p>Image: Quo.</p>
12 Jul 2017

The magazine Quo devotes an extensive report to eating habits and nutritional knowledge, including information on fats found in food.

The report also includes an interview with Salvador Aznar Benitah, ICREA researcher and group leader of the Stem Cells and Cancer Laboratory at IRB Barcelona, about his study on the relationship between fat and metastasis (cancer spread), published in Nature. The first author of this study is Gloria Pascual. 

Please see below for further information.

A two-minute animation that explains the discovery published in Nature magazine (07/12/2016):

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<p>Image: Worldwide Cancer Research.</p>
16 Jun 2017

The leading UK charity funding research into cancer, Worldwide Cancer Research, devotes a report to Salvador Aznar-Benitah's work on two new proteins that, when faulty, can allow cancer to develop. 

Published in the journal eLife, the study reports a key role for the Dnmt3a and Dnmt3b proteins in protecting cells from cancer.

Link to Worldwide Cancer Research

<p>Salvador Aznar Benitah.</p>
13 Jun 2017

The Fundación Científica Caja Rural de Soria (FCCR) presents Salvador Aznar Benitah with a prize for his research on cancer. This award is given in recognition of the "exceptional work" done by the ICREA researcher and group leader of the Stem Cells and Cancer Lab at IRB Barcelona.

As part of the award, Salvador Aznar Benitah will be presenting his findings in metastasis research in the opening session of the Soria Health Congress 2017, on October 19.

<p>Salvador Aznar Benitah leads the Stem Cells and Cancer laboratory at IRB Barcelona</p>
13 Jun 2017

The IRB Barcelona scientists is presented the prize in recognition of his research into cancer and fats.

12 Jun 2017

The radio programme "La Poma de Newton" on science, research and innovation, broadcasted by Catalunya Informació and presented by Purificación Barceló, echoes on the study led by ICREA researcher Salvador Aznar Benitah, Group leader of the Stem Cells and Cancer Laboratory at IRB Barcelona. This study identifies the cells responsible for initiating and promoting metastasis in several types of human tumours.

"When the tumours of patients that have been identified to be predisposed toward developing metastasis are stimulated with a high-fat diet or high levels of palmitic acid, they become more aggressive. Depending on the patient, a tumour is 10 or 15 times more metastatic when fed...

<p>Representative images of different subtypes of skin tumors (L. Rinaldi, IRB Barcelona)</p>
25 May 2017

Researchers led by Salvador Aznar-Benitah at IRB Barcelona investigate the role of Dnmt3a and Dnmt3b proteins in skin homeostasis and tumour development in adult mice.

The study has been published in eLife and deserved an eLife digest aimed at a more general audience.

<p>Image: iStock.</p>
1 May 2017

The renowned Austrian newspaper “Der Standard" publishes a report on palm oil and its effects on health, which has aroused the readers’ interest and generated more than 250 comments.

The article includes a reference to the research on the relationship between fat and metastasis (cancer spread) performed by Salvador Aznar Benitah and Gloria Pascual at IRB Barcelona.

This study identifies metastasis-initiating cells and suggests a major component of many types of fat, including palm oil, may help speed up the process. 

Link to "...

<p>Copyright: Getty Images.</p>
2 Apr 2017

The Huffington Post publishes an extensive report on cancer-causing mutations, with a special focus on random DNA errors that occur when self-renewing cells divide, according to a recent paper published in Science by researchers at Johns Hopkins University. 

The report includes declarations of several experts on cancer studies, among them IRB Barcelona research associates Elena Sancho, in the Colorectal Cancer Lab, and Gloria Pascual, in the Stem Cells and Cancer Lab. "Does this means that we can do as we please because whatever we do, we'll have the same probability of having cancer? The answer is a resounding no", stresses Elena Sancho. 

Link to ...