Translational control of cell cycle and differentiation news

<p>Image: CSIC</p>
20 Aug 2018

El Independiente, Catalunya Ràdio and La Vanguardia have interviewed Raúl Méndez, ICREA researcher at IRB Barcelona, to learn more about the recently published study on autism. Méndez points out that despite the importance of the discovery, "we are 'far away' from achieving a cure or solution to the autism spectrum disorder, although it will allow us to focus future studies in this direction."

Link to El Independiente

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<p>Source: Unsplash</p>
17 Aug 2018

RTVE, Ara, 20 Minutos, Daily Mail, Jornal Médico, Sic Noticias, among other national and international media, have published articles about a recent study on autism. Researchers co-led by Raúl Méndez, head of the Translational Control of Cell Cycle and Differentiation Lab at IRB Barcelona, have discovered that the protein CPEB4, a molecule that regulates protein synthesis, is impaired in most cases of autism.

Link to RTVE

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<p>Raúl Méndez and Eulàlia Belloc from the Translational Control of Cell Cycle and Differentiation Lab at IRB Barcelona</p>
16 Aug 2018

The protein CPEB4, which coordinates the expression of hundreds of genes required for neuronal activity, is altered in the brains of individuals with autism

Published in Nature, the study indicates that a defect in CPEB4 could be the link between environmental factors that alter brain development and the genes that determine susceptibility to autism

8 Jun 2018

The Asociación Española Contra el Cáncer (AECC) presents a prize for a study that reveals the capacity of the CPEB4 protein to prevent fatty liver disease.

The research was led by Raúl Méndez from IRB Barcelona and Mercedes Fernández from IDIBAPS.

<p>Gonzalo Fernández-Miranda, Project Leader and associate researcher with the Translational Control of Cell Cycle and Differentiation Lab. Image: CaixaImpulse.</p>
22 Dec 2017

El Plural has published an article on the project being undertaken by Gonzalo Fernández-Miranda, an associate researcher at IRB Barcelona. The project seeks to develop a better treatment for cancer of the head and neck by means of an immunotherapeutic approach, which has been validated with proof of concept tests at the genetic level.

Link to El Plural

12 Sep 2017

The only one of its kind in Spain, the Master offers practical training in experimental research in various disciplines at centers of excellence including IRB Barcelona.

<p>Lidia, Marcos and Irene are 3 out of the 68 "la Caixa" Phd Students 2016. Photo: Javier Barbancho (El Mundo)</p>
24 Jul 2017

IRB Barcelona PhD student Marcos Fernández is one of three researchers featured in the article published today in El Mundo, following Friday's ceremony in Madrid, where 68 young scientists received their "la Caixa" doctoral fellowships.

Since the end of 2016, this 25-year old Madrid native has been working towards his PhD degree in the Translational Control of Cell Cycle and Differentiation lab led by ICREA researcher Raúl Méndez. Marcos is studying protein synthesis in several types of tumours.

"I was considering going abroad, but this fellowship was a good incentive to stay," affirms Marcos in the article.

Read the article:...

<p>Gonzalo Fernández-Miranda, Project Leader and associate researcher with the Translational Control of Cell Cycle and Differentiation Lab. Image: CaixaImpulse.</p>
20 Jul 2017

Gonzalo Fernández-Miranda, associate researcher at IRB Barcelona, leads this therapeutic project selected by CaixaImpulse to facilitate its development towards the market.

<p>The experiments have been carried out using Xenopus laevis oocytes, an animal model used by the laboratory to study fundamental processes involved in gene regulation. Image: microscopy, Eulàlia Belloc.</p>
18 Jul 2017

Published in the journal Nature Structural & Molecular Biology, the study reveals new insights into translation regulation, an essential step in genome regulation.

These findings will help researchers to better understand pathological processes such as cancer. 

27 Apr 2017

"Saber Vivir" magazine dedicates an article to a study—co-led by Cristina Fillat, head of the Gene Therapy and Cancer Group at IDIBAPS, and Raúl Méndez, ICREA researcher at IRB Barcelona—on an innovative approach to provide an adenovirus with high specificity against tumour cells. 

The article includes Raúl Méndez's comments about the effectiveness of this new strategy to achieve genetically modified viruses that infect only tumor cells, thus preserving healthy tissues: "It would be effective in a large number of tumours".