Results about: bioinformatics

Structural biologists endorse the potential of their field to extract quality information from “big data”

International experts in structural biology, such as Nobel laureate Ada E. Yonath, and in massive genomic analysis, such as the bioinformatician Chris Sander—one of the fathers of biocomputation—, are gathering in Barcelona this week with the aim to identify synergies and throw light on the jumble of massive biological data currently available.

The Barcelona Biomed Conference organised by IRB Barcelona and the BBVA Foundation will be held from today 28 to 30 November at the Institut d’Estudis Catalans.

This afternoon, there will be an open debate on “Women in science”, chaired by Ada E. Yonath.

A minimalist theory to predict protein movements

Scientists at the Institute for Research in Biomedicine (IRB Barcelona) and the KTH Royal Institute of Technology in Stockholm develop a new method that predicts the way in which proteins move to exert their biological functions.

They have demonstrated that protein movement is governed by the general shape of these molecules, thereby providing new data on how proteins work—a key step for drug development.

Stephan-Otto: “In the near future, there’s going to be one biostatistician in every biomedical laboratory”

Camille Stephan-Otto Attolini, who holds a PhD in Biomathematics, heads the Biostatistics and Bioinformatics Core Facility at IRB Barcelona.

The “Meet Our Scientists” video “Deciphering the bytes of life” explains her work and shows us the personal side of this scientist.

Europe injects 3 million euros into three-dimensional genomics

IRB Barcelona is to coordinate a Horizon2020 bioinformatics project that seeks to lay the groundwork for the emerging field of 3D genomics.

3D genomics provides information about the structures adopted by folded DNA inside a cell and about how they change over time and in response to alterations in cell environment. Modesto Orozco, the coordinator of the project says, “The 3D perspective will allow us to better relate changes in the genome with the corresponding diseases, because although 1D information is relevant, it falls short.”

Over three years, the project aims to provide a set of methods and integrated databases that can be used to store and process the data deriving from studies devoted to 3D genomics.

The European consortium comprises six international leading centres in method development and visualisation in 3D genomics.

 

Spain joins the European consortium Elixir for managing and analysing biological data

The National Bioinformatics Institute (INB) acts as the Spanish scientific node and coordinates the partner institutions. These comprises CNIO, CRG, UPF, BSC and IRB Barcelona