Results about: brain
The group directed by Prof. Guinovart is involved in several projects on glycogen metabolism and its dysfunctions in diabetes and Lafora disease.
The protein CPEB4, which coordinates the expression of hundreds of genes required for neuronal activity, is altered in the brains of individuals with autism
Published in Nature, the study indicates that a defect in CPEB4 could be the link between environmental factors that alter brain development and the genes that determine susceptibility to autism
A new study in collaboration with the Genomic Instability and Cancer Laboratory at IRB Barcelona and led by the University of Copenhagen, reveals that TLK2 displays lower levels of activity in intellectual disability and that it is possible to inhibit it in breast cancer, where it is overactive.
The study suggests that the enzyme may be a target for potential therapies.
Researchers at IRB Barcelona reveal that the protein NEK7 is relevant for the correct formation of neurons in the hippocampus, a region of the brain associated with memory.
Animals without NEK7 may also have defects in other other brain regions.
A study co-led by IRB Barcelona and IDIBAPS emphasizes the importance of the neuronal mechanisms in the detection of nutrients and the control of glucose levels.
The results published in Cell Metabolism help to understand diabetes in greater detail.