Results about: brain

The group directed by Prof. Guinovart is involved in several projects on glycogen metabolism and its dysfunctions in diabetes and Lafora disease.

A small group of neurons modulates the amount of insulin that the pancreas must produce

A study co-led by IRB Barcelona and IDIBAPS emphasizes the importance of the neuronal mechanisms in the detection of nutrients and the control of glucose levels.

The results published in Cell Metabolism help to understand diabetes in greater detail.

Sights set on the next generation of shuttle peptides to target the brain

IRB Barcelona researchers publish a review article on the emerging field of drug transporters that have the capacity to reach the brain more efficiently.

IRB Barcelona is one of the few centres worldwide with a specific line of research devoted to this field, which brings together chemistry, pharmacy and biomedicine.

The article appears on the cover of the journal Chemical Society Reviews.

Microscopy moves towards “nanoscopy” and transforms the life sciences

The new microscopes allow the tracking of cell movement within an organism, observation of neuronal synapses, visualization of the spread of cancer, and in vivo monitoring of embryo development.

The development of the 3D microscopy, super-resolution microscopy, and light sheet microscopy (a kind of microscope that illuminates the sample with a sheet of light) pushes biology towards new horizons.

IRB Barcelona and the Centre for Genomic Regulation (CRG) gather 420 experts in the 15th ELMI Meeting, an annual European microscopy congress held this year in Sitges from 19 till 22 May.

Sports clubs, patients, and scientists unite against Pompe disease

The Asociación Española de Enfermos de Glucogenosis (AEEG) is to mark International Pompe day by organising activities throughout Spain to raise awareness of this disease and by launching a fundraising campaign to co-fund a research project at IRB Barcelona.

Pompe disease is a rare condition that causes progressive muscle degeneration. It causes death in infants under one year of age and severe muscle weakness in children and adults.

It is estimated that between 5,000 and 10,000 people worldwide suffer from this disease, which has an incidence of 1 case per 40,000 live births. In Spain, there are roughly 400 people with this condition, only 100 diagnosed.

A deficiency in a protein causes the deterioration of muscle cells. However, research into the role of motor neurons in this disease is required.