Results about: cell biology
Researchers at IRB Barcelona reveal the capacity of epithelial-derived tumours to grow in the absence of a microenvironment.
Featured on the cover of the journal Proceedings of the National Academic of Sciences (PNAS), the study identifies the cell types and molecular mechanism involved in tumour initiation and growth.
The results of this study contribute to our understanding of the internal mechanisms of the tumour, which may provide a therapeutic target.
Researchers unveil a mechanism responsible for halting protein synthesis when cells are deprived of nutrients.
The cell regulates its growth by forming various assemblies of RNA polymerase I.
The study has implications for cancer research.
These comprise a small group of passive stem cells—quiescent—that are activated when needed and have the capacity to produce any kind of intestinal cell.
Quiescent cells are relevant for tissue regeneration and for their participation in tumour development.