Results about: chemistry

A high resolution description of the structure and dynamics of proteins is a very useful tool to study the properties and the function of these important biomacromolecules and, most importantly, to understand how changes in sequence or environment can lead to disease.

Our research focuses on three angles of peptide and protein chemistry : the design, synthesis and structure of bioactive molecules. From a structural perspective, we apply modern NMR techniques to study complex molecular recognition processes.

Chiral molecules are those that are not superimposable on their mirror image. Consequently, there can be two distinct isomers of these molecules, called enantiomers. Many of the compounds associated with living organisms are chiral, for example proteins, enzymes, DNA, hormones, etc.

Building molecular complexity from scratch

The journal Science publishes a commentary article on the Pauson-Khand reaction made by an expert at IRB Barcelona

A further step towards light-controlled drugs

Researchers in Barcelona discover more potential candidates on the route to tailored, photo-switchable therapies by disproving design limitation

New angles on Alzheimer’s disease

Alzheimer’s disease has no cure and virtually no palliative treatments are available. Even today its origin is still unknown. All this has driven the international scientific community to back new approaches that allow early diagnosis of the disease and the discovery of a treatment to stop its progression. IRB Barcelona is not oblivious to this tendency. The researchers Patrick Aloy and Natàlia Carulla head projects addressing an alternative slant on the control and progression of the disease and the discovery of new therapeutic agents.

The chemist Ernest Giralt receives the main award of the European Peptide Society

The coordinator of Chemistry and Pharmacology Programme at IRB Barcelona is presented with the Josef Rudinger Memorial Lecture Award during the European Peptide Symposium, in Sofia, Bulgaria.

The award is in recognition of longstanding contributions to the field.