Results about: chemistry
Chemists at IRB Barcelona synthesize baringolin, a substance isolated from the depths of the sea by the pharmaceutical company BioMar S.A. At very small doses this compound inhibits the growth of antibiotic-resistant bacteria.
Researchers at IRB Barcelona and IBEC achieve photo-switchable molecules to control protein-protein interactions in a remote and non-invasive manner.
These tools will serve as a prototype to develop photo-switchable drugs, whose effects would be limited to a given region and time, thus reducing the side effects on other regions.
The article, cover and “Very Important Paper” of Angewandte Chemie, is a highlighted result of the European project “OpticalBullet”, funded by the European Research Council (ERC) and in which the two institutes participate.
The congress “Chemistry for Life Sciences”, being held in Barcelona, is hosting more than 200 international chemists, who answer questions and offer solutions to biomedical problems.
The European congress has been organised by IRB Barcelona researchers headed by Ernest Giralt, coordinator of the Chemistry and Molecular Pharmacology Programme.
A new technique from IRB Barcelona combines chemistry and biology to produce an exact copy of the natural molecule Thiocoraline.
Thiocoraline is a potent anti-cancer agent that is chemically very complex, isolated from a sea sponge in 1997 by the company PharmaMar.