Results about: drosophila
Genomic functions take place in chromatin, not in naked DNA.
Studies on the genetic control of development have proven to be very been fruitful in unveiling the mechanisms impaired in many disease conditions.
Genomic instability is the main risk factor for tumour development in humans. Therefore understanding its origin and exploring therapeutic targets is paramount.
Histone 1 silences a region of the genome that causes irreparable DNA damage when translated and is lethal for the organism.
M. Milán: “To study how cells communicate with each other, perhaps the best model organism is the fruit fly”
He studies the cellular and molecular mechanisms underlying the regulation of tissue growth during normal development, its proper functioning and the formation of a tumour.
Researchers at IRB Barcelona identify a fundamental role of the JAK/STAT signalling pathway in the development and growth regulation of limbs in Drosophila.
Published in Nature Communications, the study paves the way to research into the function of this pathway in vertebrate development and its possible involvement in human congenital diseases.