Results about: epigenetics


Genomic functions take place in chromatin, not in naked DNA.

While most cells in our body share almost the same exact genetic information, the way this information is read (the epigenome) is essentially unique in every single cell.

The loss of protein Dnmt3a increases the number of carcinogen-induced squamous tumours

Researchers led by Salvador Aznar-Benitah at IRB Barcelona investigate the role of Dnmt3a and Dnmt3b proteins in skin homeostasis and tumour development in adult mice.

The study has been published in eLife and deserved an eLife digest aimed at a more general audience.

International experts debate the most recent breakthroughs in oncology at the CosmoCaixa

For the fourth consecutive year, the CosmoCaixa will bring together researchers from all over the world to participate in a B·Debate, an initiative of Biocat and the Obra Social “la Caixa”. To be held on 13 and 14 October, this B.Debate organized by IRB Barcelona scientists, will address the latest advances in cancer

The morphology of the tumour cell changes when the cell migrates from one site to another, thereby allowing the cell to evade regulation and thus facilitating metastasis

Cancer relapses after chemotherapy are caused by tumour stem cells that survive the treatment


Two proteins safeguard skin stem cells

Without these proteins, skin stem cells are lost.

The study headed by Salvador Aznar Benitah at IRB Barcelona has been published today in Cell Stem Cell.