Results about: histones
Researchers at IRB Barcelona unravel the role of the histone BigH1 in the development of male sex cells from stem cells.
The study, which was performed in Drosophila melanogaster, paves the way to a greater understanding of male infertility.
Published in Cell Reports, the work sheds light on the mechanisms through which histones regulate how stem cells give rise to differentiated cells.
Genomic instability is the main risk factor for tumour development in humans. Therefore understanding its origin and exploring therapeutic targets is paramount.
Histone 1 silences a region of the genome that causes irreparable DNA damage when translated and is lethal for the organism.
Researchers at IRB Barcelona discover the molecular mechanism that determines how epigenetic markers influence gene expression
A team at IRB Barcelona identifies an essential protein for embryonic viability during the first cell divisions in the fly Drosophila.
This protein, called dBigH1, which is a variant of histone 1, could also be associated with fertility issues.