Results about: inflammation

<p>Antonio Zorzano, head of the Complex Metabolic Diseases and Mitochondria Lab</p>

Age-related metabolic diseases have increased to epidemic proportions in all industrialized countries.

A study points to new therapeutic targets for tumours associated with chronic inflammation

A new study by researchers at IRB Barcelona demonstrates that myeloid cells, which belong to the leucocyte family and form part of the innate immune system, use p38 protein signalling to support inflammation-associated colon cancer.

Published in EMBO Molecular Medicine, the study by Angel R. Nebreda suggests that inhibition of the p38 pathway in myeloid cells may be a useful therapeutic approach, especially in tumours associated with chronic inflammation.

DOR protein deficiency favours the development of obesity

Researchers at IRB Barcelona discover the mechanism that leads to a less harmful form of obesity that is associated with the number rather than volume of fat cells.

There are several types of obesity and some are more harmful than others.

The study has been published in the journal Nature Cell Biology.

The absence of a single mitochondrial protein causes severe inflammation

A study performed at IRB Barcelona supports the notion that mitochondrial defects underlie a set of diseases of unknown origin that involve chronic muscle inflammation.