Results about: mitochondria

The absence of a single protein spurs muscle aging in mice

IRB Barcelona researchers discover that the loss of the protein Mitofusin 2 in the muscles of young mice speeds up aging and causes early sarcopenia, thus leading to the muscle quality of aged mice.

Sarcopenia, which is muscle wastage and the accompanied loss of strength, is one of the most weakening conditions of old age and it has no treatment.

The scientists propose that stimulating Mitofusin 2 activity would provide a good strategy through which to ameliorate sarcopenia.

A protein that can mean life or death for cells

A research team at IRB discovers that Mitofusin 2 confers the cell with the sensitivity to understand its state of health, and determine whether it should be repaired or undergo apoptosis

With this new function, Mitofusin 2 becomes a viable target to intervene in diseases such as neurodegeneration and cancer