Results about: multiciliated cells

Research at IRB Barcelona Sheds Light on the Causes of Male Infertility

The research group led by Travis Stracker identifies genes involved in male infertility in mice.

Their findings are relevant in humans and could explain undiagnosed cases of male infertility or subfertility.

Discovery of a gene associated with a set of poorly understood rare diseases

IRB Barcelona identifies GEMC1 as a master gene for the generation of multiciliated cells—cells with fine filaments that move fluids and substances—which are found exclusively in the brain, respiratory tract, and reproductive system.

Defects in multiciliated cells lead to ciliopathies—rare and complex diseases that are poorly understood and for which not all causative genes have been identified.