Results about: nuclear magnetic resonance (NMR)

Our research focuses on three angles of peptide and protein chemistry: the design, synthesis and structure of bioactive molecules. From a structural perspective, we apply modern NMR techniques to study complex molecular recognition processes.

Researchers discover a mechanism that inhibits the Smad signalling pathway

  • A group of scientists headed by Maria Macias, ICREA researcher at IRB Barcelona, describes the mechanism through which TGIF1 inhibits the activity of Smad proteins.
  • The study, which used molecular and structural biology techniques to analyse this interaction, has been published in Nucleic Acids.

Understanding the adaptability of Smads

A study published in Nature Communications and led by Maria J Macias highlight new DNA motifs for the Smads proteins.