Results about: signalling
The Signalling and Cell Cycle Laboratory focuses on studying the basic mechanisms of cell regulation, especially regarding how external signals are interpreted by cells to modulate cell proliferation, differentiation and survival. Our research centers on two main subjects:
- A group of scientists headed by Maria Macias, ICREA researcher at IRB Barcelona, describes the mechanism through which TGIF1 inhibits the activity of Smad proteins.
- The study, which used molecular and structural biology techniques to analyse this interaction, has been published in Nucleic Acids.
M. Milán: “To study how cells communicate with each other, perhaps the best model organism is the fruit fly”
He studies the cellular and molecular mechanisms underlying the regulation of tissue growth during normal development, its proper functioning and the formation of a tumour.