Results about: structural bioinformatics

Modern molecular and cell biology no longer focus only on single macromolecules but now look into pathways, complexes or even entire organisms.

Looking for the ‘magic drug’ to fight Alzheimer’s and diabetes

Turkish-born Emre Güney (Izmir, 1983) joined IRB Barcelona in October 2015 as a Beatriu de Pinós Postodoctoral Fellow. Supporting the best young scientists, these highly competitive 2-year fellowships awarded by the Catalan Government allow them to choose the centre where they want to carry out their research project.

A step closer to putting together the vital puzzle of the bacteria Escherichia coli

E. coli is the best known model organism at the molecular level. It is used extensively for biotechnology production, and its infectious strains are of biomedical interest.

The article in Nature Biotecnology is a collaborative effort between biologists, biochemists and bioinformaticians at the Craig Venter Institute, the University of Virginia, and the Institute for Research in Biomedicine (IRB).

The team of 18 researchers presents the first map of key interactions between the molecular components of the bacteria, and allow us to understand how its most intimate machinery works.

Scientists discover a new kind of DNA intercalator

DNA intercalators developed for use in chemotherapy interfere with the DNA of cancer cells, thus eliminating them.

Researchers at IRB, in collaboration with a team in Sweden, publish the study in Angewandte Chemie.

Proteins in detail

IRB Barcelona scientists pave the way towards describing the conformation of proteins that do not have a defined structure

Structural and theoretical techniques are combined to develop new methodologies for the analysis of proteins

First structures achieved with the Alba synchrotron

Joan Roig’s team collect three-dimensional information of protein complexes involved in cell division.