Results about: therapy
Recent years have seen a paradigm shift in our understanding of gene activity and regulation. It is now clear that processing of primary transcripts as well as translational control open a myriad of opportunities for gene regulation, which are extensively used in virtually every human gene.
The Signalling and Cell Cycle Laboratory focuses on studying the basic mechanisms of cell regulation, especially regarding how external signals are interpreted by cells to modulate cell proliferation, differentiation and survival. Our research centers on two main subjects:
Colorectal Cancer (CRC) is one of the leading causes of death by cancer worldwide. Most colorectal tumors develop as benign lesions but a small proportion progress to more malignant stages when the appropriate alterations in oncogenes and tumour suppressor genes occur.
Age-related metabolic diseases have increased to epidemic proportions in all industrialized countries.
IRB Barcelona starts a project with the long-term goal to achieve an injectable frataxin treatment able to reach the brain.
Frataxin is the protein that is reduced in those affected by this rare and degenerative disease, which has no cure.
The patients’ associations Babel Family and ASOGAF in Granada provide the funding for the initial 18 months of this challenge.