The economics newspaper Expansión Catalunya has echoed the forthcoming publication of the results of a clinical assay of the MAF-Test, a diagnostic test for breast cancer patients developed by Inbiomotion, a spin-off from IRB Barcelona set up in 2010 by the researcher Roger Gomis. The results are expected to be out in November. This test may have the capacity to identify those breast cancer patients who would benefit from treatment with bisphosphonates, a class of drugs used to treat non-metastatic breast cancer, but whose administration can in many cases be counterproductive. If the results are positive, it is hoped that this test will reduce mortality...
The weekly supplement Dinero of La Vanguardia has published an article about Ona Therapeutics, the spin-off created by IRB Barcelona, ICREA and the researchers Salvador Aznar-Benitah and Valerie Vanhooren, with funding from Sabadell Asabys. Based on results published by Aznar in the journal Nature in 2017, the company aims to find a new treatment for metastatic cancer. “We found that the cells that give rise to metastasis are “addicted” to fats, and we envisaged developing a product, an antibody, that can block the protein responsible for fat uptake in these cells and thus combat their proliferation,” explains the researcher.
L’Econòmic, the weekly supplement if the local newspaper El Punt Avui, has pinpointed Ona Therapeutics, the new spin-off from IRB Barcelona, as one of the ten Catalan start-ups with greatest projection. The company, which was founded by IRB Barcelona, ICREA, and the researchers Salvador Aznar Benitah and Valerie Vanhooren, with funding from Sabadell Asabys, focuses on the development of a new drug for the treatment of metastatic cancer.
Link to L’Econòmic
Israel Ramos is a drug discovery professional specialised in in vitro assay development support to research programs and compound characterisation. With his more than 15 years of experience in the pharmaceutical industry, he is currently working at the at IRB Barcelona Innovation department as Technology Transfer Consultant. Israel provides support to IRB Barcelona researchers by giving advice about the applicability of potential drug candidates based on IRB Barcelona discoveries.
“Pharma companies have changed their model of working, and now are more open to collaboration. They are...
La Vanguardia and Expansión Catalunya, among other media, have devoted an articleto Ona Therapeutics, the new IRB Barcelona spin-off that has completed a seed financing round of 1.5 million euros, invested entirely by Sabadell Asabys. With this injection of capital, the spin-off created by IRB Barcelona, ICREA and the researchers Salvador Aznar Benitah and Valerie Vanhooren, will start up activity with the development of a new drug for the treatment of metastatic cancer.
Link to La Vanguardia
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It is estimated that one in four people will require brain treatment at some point. While there are drug candidates for most diseases of the brain, the blood-brain barrier (BBB) poses an impassable obstacle for most of these compounds and a bottleneck for the delivery of drugs that could cure these patients.
In the Peptides and Proteins Lab at the Institute for Research in Biomedicine (IRB Barcelona), Dr. Meritxell Teixidó headsa line of research that, after 10 years, has led to the development of a technology called Gate2Brain. This patented technology consists of three...
Ona Therapeutics, a spin-off from IRB Barcelona and ICREA, has been founded by researchers Salvador Aznar-Benitah and Valerie Vanhooren after receiving investment from Sabadell Asabys.
Based at the Barcelona Science Park, the company focuses on the development of a new drug for the treatment of metastatic cancer.
The Sabadell Asabys Fund, which belongs to Asabys Partners, has invested € 1.5M into the company in order to start a venture round that could reach € 20M.
Modesto Orozco’s lab has published a paper in Chemical Communications about a therapeutic tool to prevent treatment resistance in breast cancer.
The tool has been tested in tumour cells in vitro and will now need to be tested in animal models before moving on to the development of a valid treatment for patients.
La Vanguardia reports on a recent study published by Marco Milán’s lab in the journal Developmental Cell. On the basis of their findings in the fruit fly (Drosophila melanogaster), the scientists have concluded that the chromosomal instability characteristic of tumours can promote invasive behaviour in cancer.
Link to La Vanguardia: Demuestran que la inestabilidad cromosómica de tumores promueve la metástasis (in Spanish)
The digital newspaper Público and other media have echoed a study headed by the Universitat Autònoma de Barcelona (UAB) and involving researchers from the Chemistry and Molecular Pharmacology Programme at IRB Barcelona that offers a promising advance towards a treatment for Parkinson’s disease,.
Published in the journal PNAS, the study has revealed that a small molecule, called SynuClean-D, disrupts the formation of amyloid fibers of alpha-synuclein—the process that triggers the development of Parkinson’s disease—and reverses the neurodegeneration that ensues.
Jesús Garcia, Salvador Guardiola, Ernest Giralt and Xavier Salvatella are among...