Postdoc news

<p>Antonio Zorzano and his team at the Complex Metabolic Diseases and Mitochondria Lab have participated in this study. IRB Barcelona.</p>
3 May 2019

Work headed by scientist Antonio Zorzano proposes a possible therapeutic target to treat fatty liver, a disease for which there is currently no treatment. 

The study, which was done in collaboration with the Pere Virgili Institute, has been published in the journal Cell.

<p>Structure of EGFR. Purple indicates the region recognised by mAB806. Laura Orellana.</p>
2 May 2019

The antibody mAb806 is used to treat glioblastoma, although its mechanism of action has been unknown until now. 

The study, published in the journal PNAS, paves the way to extend treatment with mAb806 to more types of tumours and to the development of more personalised therapies. 

<p>Structure of the BasC transporter. Manuel Palacín, IRB Barcelona.</p>
24 Apr 2019

Mutations in L-amino acid transporters (LATs) can lead to a wide range of conditions, such as autism, hearing loss and aminoacidurias.

Published in the journal Nature Communications, this study presents key data on how amino acids bind to these transporters.

The work is a collaboration between IRB Barcelona, CIBERER, IBMB-CSIC and the Barcelona Supercomputing Center.

<p>Different localization of the proteins involved in apoptosis in basal (Ctrl) and upon death receptor induction with TRAIL. Saška Ivanova, IRB Barcelona</p>
15 Apr 2019

Many treatments against cancer, such as TRAIL, aim to trigger a type of cell death known as apoptosis.

A team at IRB Barcelona, headed by Antonio Zorzano, has demonstrated that the protein TP53INP2 induces apoptosis in chemotherapy treatments.

<p>Press conference at IRB Barcelona, presenting the #MetastasisChallenge</p>
19 Mar 2019

Through the campaign called #MetastasisChallenge, the centre aims to raise €5 M over the next four years.

Metastasis is responsible for 90% of deaths from cancer, and this campaign aims to rally social support for research in order to speed up discoveries.

<p>Marta Kovatcheva, postdoctoral researcher at IRB Barcelona</p>
1 Mar 2019

20 Minutos, La Rioja and Europa Press have published an article on the funding received by IRB Barcelona scientist Marta Kovatcheva for her studies on how to prevent lung cancer relapse after treatment. Thanks to the IV Women's Race organised by the Spanish Association Against Cancer (AECC) in La Rioja, her research will receive 160,000 euros...

<p>Gloria Pascual, Research Associate at IRB Barcelona. Picture: Fundación Pfizer</p>
19 Feb 2019

The Pfizer Foundation has awarded the IRB Barcelona scientist a prize within the “Basic Research” category.

Gloria Pascual, a member of the Stem Cells and Cancer lab, will receive €10,000 to continue her research

<p>Source: La Diaria</p>
14 Feb 2019

The Uruguayan newpaper La Diaria has published an article about recent research done by the Molecular Modelling and Bioinformatics Lab at IRB Barcelona. This team has achieved the first stable simulations of DNA crystals, thus allowing the study of the role of each molecular component in the stability and conformation of said crystals. The...

<p>Source: El Diario</p>
8 Feb 2019

The Eldiario.es portal has published an article on the "100tífiques" initiative, led by the Catalan Foundation for Research and Innovation, the Department of Education of the Generalitat de Catalunya, the Barcelona Education Consortium, and the Barcelona Institute of Science and Technology (BIST), of which IRB Barcelona forms part. In the...

<p>Picture of the three crystal systems examined in this study. These systems contain (from left to right) 27, 24 and 36 double-stranded DNA respectively. Pablo Dans Puiggròs, IRB Barcelona.</p>
21 Jan 2019

The breakthrough made by researchers at IRB Barcelona allows the study of the role of each molecular component in the stability and conformation of DNA crystals.

The new molecular simulation techniques are expected to reduce the time and cost of obtaining crystals in the laboratory.