Complex Metabolic Diseases and Mitochondria publications

Mitochondrial fission is required for cardiomyocyte hypertrophy mediated by a Ca2+-calcineurin signaling pathway

Pennanen C, Parra V, López-Crisosto C, Morales PE, Del Campo A, Gutierrez T, Rivera-Mejías P, Kuzmicic J, Chiong M, Zorzano A, Rothermel BA and Lavandero S.

J Cell Sci, 127 (Pt 12), 2659-71 (2014)

Human aquaporin-11 is a water and glycerol channel and localizes in the vicinity of lipid droplets in human adipocytes

Madeira A, Fernández-Veledo S, Camps M, Zorzano A, Moura TF, Ceperuelo-Mallafré V, Vendrell J and Soveral G.

Obesity, 22 (9), 2010-7 (2014)

Fatty acid transport protein 1 (FATP1) localizes in mitochondria in mouse skeletal muscle and regulates lipid and ketone body disposal

Guitart M, Osorio-Conles O, Pentinat T, Cebrià J, García-Villoria J, Sala D, Sebastián D, Zorzano A, Ribes A, Jiménez-Chillarón JC, García-Martínez C and Gómez-Foix AM.

PLoS One, 9 (5), e98109 (2014)

A gold coordination compound as a chemical probe to unravel aquaporin-7 function

Madeira A, de Almeida A, de Graaf C, Camps M, Zorzano A, Moura TF, Casini A and Soveral G.

Chembiochem, 15 (10), 1487-94 (2014)

The p38α MAPK function in osteoprecursors is required for bone formation and bone homeostasis in adult mice

Rodríguez-Carballo E, Gámez B, Sedó-Cabezón L, Sánchez-Feutrie M, Zorzano A, Manzanares-Céspedes C, Rosa JL and Ventura F.

PLoS One, 9 (7), e102032 (2014)

The DEXLIFE study methods: Identifying novel candidate biomarkers that predict progression to type 2 diabetes in high risk individuals

Andersen GS, Thybo T, Cederberg H, Orešič M, Esteller M, Zorzano A, Carr B, Walker M, Cobb J, Clissmann C, O'Gorman DJ, Nolan JJ and DEXLIFE Consortium.

Diabetes Res Clin Pr, 106 (2), 383-9 (2014)

Mfn2 downregulation in excitotoxicity causes mitochondrial dysfunction and delayed neuronal death

Martorell-Riera A, Segarra-Mondejar M, Muñoz JP, Ginet V, Olloquequi J, Pérez-Clausell J, Palacín M, Reina M, Puyal J, Zorzano A and Soriano FX.

Embo J, 33 (20), 2388-407 (2014)

(13)C metabolic flux analysis shows that resistin impairs the metabolic response to insulin in L6E9 myotubes

Guzmán S, Marin S, Miranda A, Selivanov VA, Centelles JJ, Harmancey R, Smih F, Turkieh A, Durocher Y, Zorzano A, Rouet P and Cascante M.

BMC Syst Biol, 8 (1), 109 (2014)

Autophagy-regulating TP53INP2 mediates muscle wasting and is repressed in diabetes

Sala D, Ivanova S, Plana N, Ribas V, Duran J, Bach D, Turkseven S, Laville M, Vidal H, Karczewska-Kupczewska M, Kowalska I, Straczkowski M, Testar X, Palacín M, Sandri M, Serrano AL and Zorzano A.

J Clin Invest, 124 (5), 1914-27 (2014)

Structural bases for the interaction and stabilization of the human amino acid transporter LAT2 with its ancillary protein 4F2hc

Rosell A, Meury M, Álvarez-Marimon E, Costa M, Pérez-Cano L, Zorzano A, Fernández-Recio J, Palacín M and Fotiadis D.

P Natl Acad Sci Usa, 111 (8), 2966-71 (2014)