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Investigación

A la vanguardia de la biomedicina

Publicaciones sobre Investigación

MicroRNA-Mediated Regulation of Dp53 in the Drosophila Fat Body Contributes to Metabolic Adaptation to Nutrient Deprivation
Barrio, L; Dekanty, A; Milán, M
Cell Reports
8
2
527 -
540
2014
Analogs of natural aminoacyl-tRNA synthetase inhibitors clear malaria in vivo
Novoa, EM; Camacho, N; Tor, A; Wilkinson, B; Moss, S; Marín-García, P; Azcárate, IG; Bautista, JM; Mirando, AC; Francklyn, CS; Varon, S; Royo, M; Cortés, A; de Pouplana, LR
Proceedings Of The National Academy Of Sciences Of The United States Of America
111
51
E5508 -
E5517
2014
RAB7 controls melanoma progression by exploiting a lineage-specific wiring of the endolysosomal pathway
Alonso-Curbelo D, Riveiro-Falkenbach E, Pérez-Guijarro E, Cifdaloz M, Karras P, Osterloh L, Megías D, Cañón E, et al, [corr. author] Soengas MS.
Cancer Cell
2014
The solute carrier SLC35F2 enables YM155-mediated DNA damage toxicity
Winter G.E., Radic B. (#), Mayor-Ruiz C. (#), Blomen V.A., Trefzer C., Kandasamy R.K., Huber K.V.M., Gridling M., Chen D., Klampfl T., Kralovics R., Kubicek S., Fernandez-Capetillo O., Brummelkamp T.R., Superti-Furga G. (# Equal contribution)
Nat Chem Bio
10
768 -
773
2014
Inhibition of p38 MAPK sensitizes tumour cells to cisplatin-induced apoptosis mediated by reactive oxygen species and JNK
Pereira, L; Igea, A; Canovas, B; Dolado, I; Nebreda, AR
Embo Molecular Medicine
5
11
1759 -
1774
2013
Multi-phosphorylation of the intrinsically disordered unique domain of c-src studied by in-cell and real-time NMR spectroscopy
Amata, I; Maffei, M; Igea, A; Gay, M; Vilaseca, M; Nebreda, AR; Pons, M
Chembiochem
14
14
1820 -
1827
2013
Human mitochondrial disease-like symptoms caused by a reduced tRNA aminoacylation activity in flies
Guitart, T; Picchioni, D; Pineyro, D; de Pouplana, LR
Nucleic Acids Research
41
13
6595 -
6608
2013
On the origin of the selectivity of plasmidic H-NS towards horizontally acquired DNA: Linking H-NS oligomerization and cooperative DNA binding
Fernández-de-Alba, C; Berrow, NS; Garcia-Castellanos, R; García, J; Pons, M
Journal Of Molecular Biology
425
13
2347 -
2358
2013
Applications and future of ion mobility mass spectrometry in structural biology
López, A; Tarragó, T; Vilaseca, M; Giralt, E
New Journal Of Chemistry
37
5
1283 -
1289
2013
Drosophila melanogaster: A model and a tool to investigate malignancy and identify new therapeutics
Gonzalez, C
Nature Reviews Cancer
13
3
172 -
183
2013
Bantam miRNA promotes systemic growth by connecting insulin signaling and ecdysone production
Boulan, L; Martín, D; Milán, M
Current Biology
23
6
473 -
478
2013
SnapShot: P38 MAPK substrates
Trempolec N; Dave-Coll N; Nebreda A
Cell
152
4
924 -
924.e1
2013
Characterization of superoxide dismutase 1 (SOD-1) by electrospray ionization-ion mobility mass spectrometry
Borges-Alvarez, M; Benavente, F; Vilaseca, M; Barbosaa, J; Sanz-Nebot, V
Journal Of Mass Spectrometry
48
1
60 -
67
2013
Coordinated control of replication and transcription by a SAPK protects genomic integrity
Duch, Alba; Felipe-Abrio, Irene; Barroso, Sonia; Yaakov, Gilad; Garcia-Rubio, Maria; Aguilera, Andres; de Nadal, Eulalia; Posas, Francesc
Nature
493
7430
116 -
119
2013
Centrobin controls mother-daughter centriole asymmetry in Drosophila neuroblasts
Januschke, J; Reina, J; Llamazares, S; Bertran, T; Rossi, F; Roig, J; Gonzalez, C
Nature Cell Biology
15
3
241 -
248
2013
CPEB1 coordinates alternative 3''-UTR formation with translational regulation
Bava, FA; Eliscovich, C; Ferreira, PG; Miñana, B; Ben-Dov, C; Guigó, R; Valcárcel, J; Méndez, R
Nature
495
7439
121 -
125
2013
Force communication in multicellular tissues addressed by laser nanosurgery
Colombelli, J; Solon, J
Cell And Tissue Research
352
1
133 -
147
2013
Fabrication of hierarchical micro-nanotopographies for cell attachment studies
López-Bosque, MJ; Tejeda-Montes, E; Cazorla, M; Linacero, J; Atienza, Y; Smith, KH; Lladó, A; Colombelli, J; Engel, E; Mata, A
Nanotechnology
24
25
255305 -
255305
2013
Light-regulated stapled peptides to inhibit protein-protein interactions involved mediated endocytosis
Nevola, L; Martín-Quirós, A; Eckelt, K; Camarero, N; Tosi, S; Llobet, A; Giralt, E; Gorostiza, P
Angewandte Chemie (International Ed. Print)
52
30
7704 -
7708
2013
The SLC3 and SLC7 families of amino acid transporters
Fotiadis, D; Kanai, Y; Palacín, M
Molecular Aspects Of Medicine
34
2-3
139 -
158
2013
Mfn2 modulates the UPR and mitochondrial function via repression of PERK
Muñoz, JP; Ivanova, S; Sánchez-Wandelmer, J; Martínez-Cristóbal, P; Noguera, E; Sancho, A; Díaz-Ramos, A; Hernández-Alvarez, MI; Sebastián, D; Mauvezin, C; Palacín, M; Zorzano, A
Embo Journal
32
17
2348 -
2361
2013
Synthesis and application of beta-substituted Pauson-Khand adducts: trifluoromethyl as a removable steering group
Aiguabella, N; del Pozo, C; Verdaguer, X; Fustero, S; Riera, A
Angewandte Chemie (International Ed. Print)
52
20
5355 -
5359
2013
The embryonic linker histone H1 variant of Drosophila, dBigH1, regulates zygotic genome activation
Pérez-Montero, S; Carbonell, A; Morán, T; Vaquero, A; Azorín, F
Developmental Cell
26
6
578 -
590
2013
IntOGen-mutations identifies cancer drivers across tumor types
Gonzalez-Perez, Abel; Perez-Llamas, Christian; Deu-Pons, Jordi; Tamborero, David; Schroeder, Michael P; Jene-Sanz, Alba; Santos, Alberto; Lopez-Bigas, Nuria
Nature Methods
10
11
1081 -
1082
2013
Stereodivergent S(N)2@P Reactions of Borane Oxazaphospholidines: Experimental and Theoretical Studies
Zijlstra, H; León, T; de Cózar, A; Guerra, CF; Byrom, D; Riera, A; Verdaguer, X; Bickelhaupt, FM
Journal Of The American Chemical Society
135
11
4483 -
4491
2013
Dependency of Colorectal Cancer on a TGF-beta-Driven Program in Stromal Cells for Metastasis Initiation
Calon, A; Espinet, E; Palomo-Ponce, S; Tauriello, DVF; Iglesias, M; Céspedes, MV; Sevillano, M; Nadal, C; Jung, P; Zhang, XHF; Byrom, D; Riera, A; Rossell, D; Mangues, R; Massagué, J; Sancho, E; Batlle, E
Cancer Cell
22
5
571 -
584
2012
Reprogramming cell shape with laser nano-patterning
Vignaud, T; Galland, R; Tseng, QZ; Blanchoin, L; Colombelli, J; Théry, M
Journal Of Cell Science
125
9
2134 -
2140
2012
htSeqTools: High-throughput sequencing quality control, processing and visualization in R
Planet, E; Attolini, CSO; Reina, O; Flores, O; Rossell, D
Bioinformatics
28
4
589 -
590
2012
Pten positively regulates brown adipose function, energy expenditure, and longevity
Muñoz Martin, Maria Angeles; Ortega-Molina, Ana; Efeyan, Alejo; Lopez-Guadamillas, Elena; Munoz-Martin, Maribel; Gomez-Lopez, Gonzalo; Canamero, Marta; Mulero, Francisca; Pastor, Joaquin; Martinez, Sonia; Romanos, Eduardo; Mar Gonzalez-Barroso, M; Rial, Eduardo; Valverde, Angela M; Bischoff, James R; Serrano, Manuel
Cell Metabolism
15
3
382 -
394
2012
Key contribution of CPEB4-mediated translational control to cancer progression
Ortiz-Zapater, E; Pineda, D; Martínez-Bosch, N; Fernández-Miranda, G; Iglesias, M; Alameda, F; Moreno, M; Eliscovich, C; Eyras, E; Real, FX; Méndez, R; Navarro, P
Nature Medicine
18
1
83 -
90
2012
The p57 CDKi integrates stress signals into cell-cycle progression to promote cell survival upon stress
Joaquin M; Gubern A; González-Nuñez D; Josué Ruiz E; Ferreiro I; De Nadal E; Nebreda A; Posas F
Embo Journal
31
13
2952 -
2964
2012
Structure of triplex DNA in the Gas phase
Arcella, A; Portella, G; Ruiz, ML; Eritja, R; Vilaseca, M; Gabelica, V; Orozco, M
Journal Of The American Chemical Society
134
15
6596 -
6606
2012
Deleterious effects of neuronal accumulation of glycogen in flies and mice
Duran, J; Tevy, MF; Garcia-Rocha, M; Calbó, J; Milán, M; Guinovart, JJ
Embo Molecular Medicine
4
8
719 -
729
2012
Aneuploidy-induced delaminating cells drive tumorigenesis in Drosophila epithelia
Dekanty, A; Barrio, L; Muzzopappa, M; Auer, H; Milán, M
Proceedings Of The National Academy Of Sciences Of The United States Of America
109
50
20549 -
20554
2012
A Role for tRNA Modifications in Genome Structure and Codon Usage
Novoa, EM; Pavon-Eternod, M; Pan, T; de Pouplana, LR
Cell
149
1
202 -
213
2012
Mitofusin 2 (Mfn2) links mitochondrial and endoplasmic reticulum function with insulin signaling and is essential for normal glucose homeostasis.
Sebastián, D; Hernández-Alvarez, MI; Segalés, J; Sorianello, E; Muñoz, JP; Sala, D; Waget, A; Liesa, M; Paz, JC; Gopalacharyulu, P; Oresic, M; Pich, S; Burcelin, R; Palacín, M; Zorzano, A
Proceedings Of The National Academy Of Sciences Of The United States Of America
109
14
5523 -
5528
2012
P-Stereogenic Secondary Iminophosphorane Ligands and Their Rhodium(I) Complexes: Taking Advantage of NH/PH Tautomerism
León, T; Parera, M; Roglans, A; Riera, A; Verdaguer, X
Angewandte Chemie (International Ed. Print)
51
28
6951 -
6955
2012
Fine-tuning the p-p Aromatic Interactions in Peptides: Somatostatin Analogues Containing Mesityl Alanine
Martín-Gago, P; Gomez-Caminals, M; Ramón, R; Verdaguer, X; Martin-Malpartida, P; Aragón, E; Fernández-Carneado, J; Ponsati, B; López-Ruiz, P; Cortes, MA; Colás, B; Macias, MJ; Riera, A
Angewandte Chemie (International Ed. Print)
51
8
1820 -
1825
2012
Combined bottom-up and top-down mass spectrometry analyses of the pattern of post-translational modifications of Drosophila melanogaster linker histone H1
Bonet-Costa, C; Vilaseca, M; Diema, C; Vujatovic, O; Vaquero, A; Omeñaca, N; Castejón, L; Bernués, J; Giralt, E; Azorín, F
Journal Of Proteomics
75
13
4124 -
4138
2012
Drosophila melanogaster linker histone dH1 is required for transposon silencing and to preserve genome integrity
Vujatovic, O; Zaragoza, K; Vaquero, A; Reina, O; Bernués, J; Azorín, F
Nucleic Acids Research
40
12
5402 -
5414
2012
Viscoelastic response of contractile filament bundles
Besser, A; Colombelli, J; Stelzer, EHK; Schwarz, US
Physical Review e
83
5
051902 -
051902
2011
Isolation and in vitro expansion of human colonic stem cells
Jung, P; Sato, T; Merlos-Suárez, A; Barriga, FM; Iglesias, M; Rossell, D; Auer, H; Gallardo, M; Blasco, MA; Sancho, E; Clevers, H; Batlle, E
Nature Medicine
17
10
1225 -
1227
2011
Specific GATA Factors Act as Conserved Inducers of an Endodermal-EMT
Campbell, K; Whissell, G; Franch-Marro, X; Batlle, E; Casanova, J
Developmental Cell
21
6
1051 -
1061
2011
Controlling gene expression in response to stress
De Nadal E; Ammerer G; Posas F
Nature Reviews Genetics
12
12
833 -
845
2011
Human mitochondrial transcription factor A induces a U-turn structure in the light strand promoter
Rubio-Cosials, A; Sidow, JF; Jiménez-Menéndez, N; Fernández-Millán, P; Montoya, J; Jacobs, HT; Coll, M; Bernadó, P; Solà, M
Nature Structural & Molecular Biology
18
11
1281 -
U133
2011
Control of Ubp3 ubiquitin protease activity by the Hog1 SAPK modulates transcription upon osmostress
Solé C; Nadal-Ribelles M; Kraft C; Peter M; Posas F; De Nadal E
Embo Journal
30
16
3274 -
3284
2011
Neurodegeneration and functional impairments associated with glycogen synthase accumulation in a mouse model of Lafora disease
Valles-Ortega, J; Duran, J; Garcia-Rocha, M; Bosch, C; Saez, I; Pujadas, L; Serafin, A; Cañas, X; Soriano, E; Delgado-García, JM; Gruart, A; Guinovart, JJ
Embo Molecular Medicine
3
11
667 -
681
2011
The F box protein partner of paired regulates stability of drosophila centromeric histone H3, CenH3 CID
Moreno-Moreno, O; Medina-Giró, S; Torras-Llort, M; Azorín, F
Current Biology
21
17
1488 -
1493
2011