Translational Control of Cell Cycle and Differentiation publications

Autism-like phenotype and risk gene mRNA deadenylation by CPEB4 mis-splicing

Parras A, Anta H, Santos-Galindo M, Swarup V, Elorza A, Nieto-González JL, Picó S, Hernández IH, Díaz-Hernández JI, Belloc E, Rodolosse A, Parikshak NN, Peñagarikano O, Fernández-Chacón R, Irimia M, Navarro P, Geschwind DH, Méndez R and Lucas JJ.

Nature, 560 (7719), 441-446 (2018)

Regulation of Adult CNS Axonal Regeneration by the Post-transcriptional Regulator Cpeb1

Lou WP, Mateos A, Koch M, Klussman S, Yang C, Lu N, Kumar S, Limpert S, Göpferich M, Zschaetzsch M, Sliwinski C, Kenzelmann M, Seedorf M, Maillo C, Senis E, Grimm D, Puttagunta R, Mendez R, Liu K, Hassan BA and Martin-Villalba A.

Front Mol Neurosci, 10 445 (2018)

Musashi 1 regulates the timing and extent of meiotic mRNA translational activation by promoting the use of specific CPEs

Weill L, Belloc E, Castellazzi CL and Méndez R.

Nat Struct Mol Biol, 24 (8), 672-681 (2017)

Translational reprogramming in tumour cells can generate oncoselectivity in viral therapies

Villanueva E, Navarro P, Rovira-Rigau M, Sibilio A, Méndez R and Fillat C.

Nat Commun, 8 14833 (2017)

Circadian- and UPR-dependent control of CPEB4 mediates a translational response to counteract hepatic steatosis under ER stress

Maillo C, Martín J, Sebastián D, Hernández-Alvarez M, García-Rocha M, Reina O, Zorzano A, Fernandez M and Méndez R.

Nat Cell Biol, 19 (2), 94-105 (2017)

The In Vivo Architecture of the Exocyst Provides Structural Basis for Exocytosis

Picco A, Irastorza-Azcarate I, Specht T, Böke D, Pazos I, Rivier-Cordey AS, Devos DP, Kaksonen M and Gallego O.

Cell, 168 (3), 400-412.e1 (2017)

Role and therapeutic potential of vascular stem/progenitor cells in pathological neovascularisation during chronic portal hypertension

Garcia-Pras E, Gallego J, Coch L, Mejias M, Fernandez-Miranda G, Pardal R, Bosch J, Mendez R and Fernandez M.

Gut, 66 (7), 1306-1320 (2017)

Lineage-specific roles of the cytoplasmic polyadenylation factor CPEB4 in the regulation of melanoma drivers

Pérez-Guijarro E, Karras P, Cifdaloz M, Martínez-Herranz R, Cañón E, Graña O, Horcajada-Reales C, Alonso-Curbelo D, Calvo TG, Gómez-López G, Bellora N, Riveiro-Falkenbach E, Ortiz-Romero PL, Rodríguez-Peralto JL, Maestre L, Roncador G, de Agustín Asensio JC, Goding CR, Eyras E, Megías D, Méndez R and Soengas MS.

Nat Commun, 7 13418 (2016)

CPEB4 is regulated during cell cycle by ERK2/Cdk1-mediated phosphorylation and its assembly into liquid-like droplets

Guillén-Boixet J, Buzon V, Salvatella X and Méndez R.

Elife, 5 (2016)

Glycogen Synthase in Sertoli Cells: More Than Glycogenesis?

Maldonado R, Mancilla H, Villarroel-Espíndola F, Slebe F, Slebe JC, Méndez R, Guinovart JJ and Concha II.

J Cell Biochem, 117 (11), 2597-607 (2016)