Biostatistics/Bioinformatics Unit / Biostatistics / Bioinformatics Unit / Core Facilities & Services / IRB Barcelona

Biostatistics/Bioinformatics Unit

David Rossell

Core Facility Manager

Office Tel : +34 93 40 20217

e-mail : david.rossellirbbarcelona.org

Background

The mission of the Biostatistics/Bioinformatics Unit is to conduct collaborative research and to provide consultation and quantitative research resources to all IRB Barcelona research groups.

We assist scientists by providing both short and long-term consultancy services in the following areas:

Experimental design: sample size, study design, planning of statistical methodology
Data analysis: clinical or biomedical databases, genomics data
Assistance with statistical methodology in own or others’ research
Software: help in using software, develop software to meet special data analysis or study design needs

The facility conducts methodological research and develops resources in all of the above-mentioned areas.

For more information contact the manager of the Biostatistics/Bioinformatics Unit at
david.rossell arroba irbbarcelona.org.

More info

Biostatistics/Bioinformatics Unit

Core Facility Manager
David Rossell
tel +34 93 40 20217
e-mail: david.rossellirbbarcelona.org

Senior Research Officer
Camille Stephan
tel +34 93 40 20553
e-mail: camille.stephanirbbarcelona.org

Evarist Planet
tel +34 93 40 20553
e-mail: evarist.planetirbbarcelona.org

Research Officers
Oscar Reina
tel +34 93 40 20553
e-mail: oscar.reinairbbarcelona.org

Biostatistics/Bioinformatics Unit

Selected publications

Bayesian model selection in High-dimensional settings
Johnson, V.E. and Rossell, D.
J Am Stat Assoc ((in press)) (2012)

htSeqTools: High-Throughput Sequencing Quality Control, Processing and Visualization in R
Planet E, Stephan-Otto Attolini C, Reina O, Flores O and Rossell D.
Bioinformatics (2011)

The intestinal stem cell signature identifies colorectal cancer stem cells and predicts disease relapse
Merlos-Suárez A, Barriga FM, Jung P, Iglesias M, Céspedes MV, Rossell D, Sevillano M, Hernando-Momblona X, da Silva-Diz V, Muñoz P, Clevers H, Sancho E, Mangues R and Batlle E.
Cell Stem Cell, 5 (8), 511-24 (2011)

Non-Local prior densities for default Bayesian hypothesis tests
Johnson, V.E. and Rossell, D.
J Roy Stat Soc B (72), 143-170 (2010)

Ectopic expression of germline genes drives malignant brain tumor growth in Drosophila
Janic A, Mendizabal L, Llamazares S, Rossell D and Gonzalez C.
Science, 6012 (330), 1824-7 (2010)

GaGa: a parsimonious and flexible model for diferential expression analysis
Rossell D
Ann Appl Stat, 3 (3), 1035-51 (2009)

Drosophila HP1c isoform interacts with the zinc-finger proteins WOC and Relative-of-WOC to regulate gene expression
Font-Burgada J, Rossell D, Auer H and Azorín F
Gene Dev, 21 (22), 3007-23 (2008)

All publications list

Deep sequence analysis of non-small cell lung cancer: integrated analysis of gene expression, alternative splicing, and single nucleotide variations in lung adenocarcinomas with and without oncogenic KRAS mutations
Kalari KR, Rossell D, Necela BM, Asmann YW, Nair A, Baheti S, Kachergus JM, Younkin CS, Baker T, Carr JM, Tang X, Walsh MP, Chai H-S, Sun Z, Hart SN, Leontovich AA, Hossain A, Kocher J-P, Perez EA, Reisman DN, Fields AP and Thompson EA
Front. Oncol., 12 (2) (2012)

Transcriptional variation in the malaria parasite Plasmodium falciparum
Rovira-Graells N, Gupta AP, Planet E, Crowley VM, Mok S, Ribas de Pouplana L, Preiser PR, Bozdech Z and Cortés A.
Genome Res (2012)

Drosophila melanogaster linker histone dH1 is required for transposon silencing and to preserve genome integrity
Vujatovic O, Zaragoza K, Vaquero A, Reina O, Bernués J and Azorín F.
Nucleic Acids Res (2012)

Tumor-stroma interactions a trademark for metastasis
Morales M, Planet E, Arnal-Estape A, Pavlovic M, Tarragona M, Gomis RR
Breast, 3 (20), S50-S55 (2011)

Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph
Casabonne D, Reina O, Benavente Y, Becker N, Maynadié M, Foretová L, Cocco P, González-Neira A, Nieters A, Boffetta P, Middeldorp JM and de Sanjose S.
Haematol-hematol J, 2 (96), 323-7 (2011)

Chimeric tRNAs as tools to induce proteome damage and identify components of stress responses
Geslain R, Cubells L, Bori-Sanz T, Alvarez-Medina R, Rossell D, Martí E and de Pouplana LR.
Nucleic Acids Res, 5 (38), e30 (2010)

Semi-parametric differential expression analysis via partial mixture estimation
Rossell D, Guerra R and Scott C
Stat Appl Genet Mol Biol, 1 (7), Article 15 (2008)

Biostatistics/Bioinformatics Unit

29 April 2011
Institute News
NIH of the United States to finance a large-scale cancer genetics project undertaken by IRB Barcelona
Researchers at IRB Barcelona are to collaborate with international institutes to study the genetic code that determines cancer cell activity.
2 November 2010
seminar
Statistical Approaches to Protein Quantitation Shotgun Proteomic and DanTER [+ info]
Speaker: Yuliya Karpievitch
Pacific Northwest national Lab, Richland (WA, USA)
Time/Place: 12.00h, Fèlix Serratosa Room
3 May 2010
Seminar
Partek Microarray & Next-Generation Sequencing Data Analysis Workshop
Hosted by IRB Barcelona's Biostatistics and Bioinformatics Unit
Barcelona, Spain. 3-5 May 2010
22 January 2010
Science Careers
Statistics serving biomedicine

Core Facilities & Services

Core Facilities & Services

Biostatistics/Bioinformatics Unit

Background

More info

Biostatistics/Bioinformatics Unit

Biostatistics/Bioinformatics Unit

Biostatistics/Bioinformatics Unit

Scientific publications search

Research Directory

Core facilities and Services Directory

Follow us on