Prostate cancer, Alzheimer’s, Parkinson’s...these three diseases are associated with proteins that share a common feature, namely disordered regions that have no apparent rigid three-dimensional st
Camille Stephan-Otto Attolini (Mexico, 1978) knows one thing for sure: biostatistics in the health sciences is here to stay.
Our skin renews, heals wounds, and regenerates the hair that covers it thanks to a small group of stem cells.
El Heraldo de Aragón
Ideal de Granada
Local, national and international headlines have echoed the study on a new epigenetic mechanism that ensures the maintenance of skin stem cells. The study, done by ICREA researcher Salvador Aznar Benitah and published in Cell Stem Cell, provides further information on the basic biology and regulation of stem cells in a constantly renewing tissue.
Local media have devoted considerable attention to the award of the Catalonia International Award (Premi Internacional de Catalunya), presented by the Government of Catalonia, to Joan Massagué, Josep Baselga, and Manel Esteller.
Felice Alessio Bava
former PhD student in the Translational Control of Cell Cycle and Differentiation Lab
«We suspected that CPEB1, a protein involved in regulating mRNA translation in the cytoplasm, might also be active in the nucleus and play a role in controlling pre-mRNA processing. We discovered that it affects the alternative generation in the mature mRNA of the 3'-UTR, regions where most of the elements regulating translation in time and space are located.»
More info about this news here.
«Our study highlights the complexity of p38 functions, both in cancer and in the maintenance of normal tissues. It shows why an inhibitor of this molecule could effectively have undesirable side effects. But these do not exclude it from being a target against cancer.»
More on this news here.
«Controlling a biological process from outside is the future of chemistry and opens up promising roads for advancements in pharmacological research.»
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«98% of the potential therapeutic molecules against diseases of the central nervous system cannot cross the blood-brain barrier. We develop peptides with the capacity to open the doors of the barrier and act as shuttles when attached to a therapeutic molecule.»
Quick facts about IRB
IRB Barcelona has been awarded the "HR Excellence in Research" logo. This recognition reflects the commitment of the Institute to continuously improving its human resources policies in line with the European Charter for Researchers and the Code of Conduct for the Recruitment of Researchers. The award confirms the efforts of the Institute to ensure fair and transparent recruitment and appraisal procedures. Click here for more information.
IRB Barcelona is home to nearly 450 research, technical and support staff from 35 countries who share the common goal of contributing to the advancement of the biomedical sciences through investigator–driven research, and improving quality of life by applying advances in this field.
The convergence of biology, chemistry, and structural and computational biology is unique at IRB Barcelona and opens a strategic window to gain insight into basic molecular processes in health and disease.
Research is conducted by 23 groups organized into 5 interdisciplinary programmes. Each programme includes a diverse faculty of researchers with overlapping scientific interests. The research areas have been structured to be highly interactive, fostering multidisciplinarity by combining modern molecular biology, classical genetics, biochemistry, structural biology, bioinformatics, systems biology, advanced microscopy, and genomic and proteomic approaches.