One kind of stem cell, those referred to as ‘facultative’, form part—together with other cells—of tissues and organs. There is apparently nothing that differentiates these cells from the others.
Co-founder of the Institute for Research in Biomedicine (IRB Barcelona) and Chair of its External Advisory Board, Joan Massagué, has been awarded the Spanish National Research Award for 2014, in th
Today the Institute for Research in Biomedicine (IRB Barcelona) has launched an innovative video – featuring its scientists as dancers.
Researchers at the Institute for Research in Biomedicine (IRB Barcelona) have managed to generate a fruit fly (Drosophila melanogaster) model that reproduces human colon cancer.
Scientia Crastina is a platform aimed at early career scientists for the
discussion of academic communication and the dissemination of science.
They have seen the IRB Barcelona video and devoted an article to it with
quotes from Sarah Sherwood, head of the Communications and External
Relations of IRB Barcelona and main coordinator of the video.
Diario Médico reports on a study by Ernest Giralt’s lab (two pages) published in the Journal of Controlled Release on the design of a peptide capable of eliminating tumour cells. The peptide in question exploits the properties of wasp venom.
The magazine Quo has published an article by Cristina Sáez on the breakthroughs and future treatments for cancer. Among the many scientists cited is ICREA researcher Salvador Aznar Benitah (IRB Barcelona) for his studies on stem cells and skin cancer.
«Controlling a biological process from outside is the future of chemistry and opens up promising roads for advancements in pharmacological research.»
More info on this news here.
Felice Alessio Bava
ex PhD student in the Translational Control of Cell Cycle and Differentiation Lab
«We suspected that CPEB1, a protein involved in regulating mRNA translation in the cytoplasm, might also be active in the nucleus and play a role in controlling pre-mRNA processing. We discovered that it affects the alternative generation in the mature mRNA of the 3'-UTR, regions where most of the elements regulating translation in time and space are located.»
More info about this news here.
«98% of the potential therapeutic molecules against diseases of the central nervous system cannot cross the blood-brain barrier. We develop peptides with the capacity to open the doors of the barrier and act as shuttles when attached to a therapeutic molecule.»
«Our study highlights the complexity of p38 functions, both in cancer and in the maintenance of normal tissues. It shows why an inhibitor of this molecule could effectively have undesirable side effects. But these do not exclude it from being a target against cancer.»
More on this news here.
Quick facts about IRB
IRB Barcelona is home to nearly 450 research, technical and support staff from 35 countries who share the common goal of contributing to the advancement of the biomedical sciences through investigator–driven research, and improving quality of life by applying advances in this field.
The convergence of biology, chemistry, and structural and computational biology is unique at IRB Barcelona and opens a strategic window to gain insight into basic molecular processes in health and disease.
Research is conducted by 23 groups organized into 5 interdisciplinary programmes. Each programme includes a diverse faculty of researchers with overlapping scientific interests. The research areas have been structured to be highly interactive, fostering multidisciplinarity by combining modern molecular biology, classical genetics, biochemistry, structural biology, bioinformatics, systems biology, advanced microscopy, and genomic and proteomic approaches.
IRB Barcelona is housed within the Barcelona Science Park on the University of Barcelona Pedralbes Campus. It is an integral part of the ‘Bioregion of Catalonia’, a rich landscape of research centres of excellence, universities, science parks, hospitals, scientific infrastructures and pharmaceutical companies, all with a focus on the life sciences. It is a member of the CERCA network of government research centres.