On Monday, the weekly medical newspaper “Gaceta Médica” reported on the study published in the journal Nature Genetics by the Colorectal Cancer Laboratory at IRB Barcelona, led by ICREA researcher Eduard Batlle. This study associates the alterations caused by colon tumour cells in healthy cells in surrounding tissues, called stroma, with the probability of developing subsequent metastasis.
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The computational tool developed by the Laboratory of Structural Bioinformatics and Network Biology at IRB Barcelona, led by ICREA researcher Patrick Aloy, associates 23,000 genetic mutations with various complex diseases such as cancer, Alzheimer’s and diabetes. The presentation of the dSysMap tool in the journal Nature Methods, and its inclusion in the international consortium Pan-Cancer for the analysis of human tumours have had a considerable impact in the media, among these the “Diari de Girona”.
The work of the Colorectal Cancer Laboratory published in Nature Genetics on the molecular classification of colon tumors has had a great impact on the media. The study shows that the malignancy of tumors lies in whether the cells surrounding the tumor are altered or not. The news highlights the promise that the results hold to develop a diagnostic test to predict the risk of metastasis in patients. Another striking result is the proposal to start clinical trials using inhibitors of an experimental drug that has proven to halt metastasis in mice.
TV3 News has broadcasted a report on a shuttle molecule capable of crossing the barrier that protects the brain from infections and of transporting therapeutic molecules into this organ —a development patented by members of the Peptides and Proteins Laboratory at IRB Barcelona, headed by Ernest Giralt, also full professor at the UB. In the report, Giralt explains how this shuttle works. His lab is already working on the applications of this shuttle in three projects to treat various diseases that affect the brain.
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“El Mundo” has produced an article to mark the publication of 24 papers on epigenetics in journals belonging to the Nature group. These papers are the result of the endeavours of hundreds of scientists participating in the Epigenomics Mapping Programme, launched by the USA National Institutes of Health (NIH) in 2008, and its European equivalent project, called Blueprint Epigenome. The article includes statements by Ferran Azorín, group leader of the Chromatin Structure and Function Laboratory at IRB Barcelona and CSIC research professor.
“Diario Médico” has interviewed Antonio Zorzano, group leader of the Complex Metabolic Diseases and Mitochondria Laboratory at IRB Barcelona and full professor at the UB. Zorzano is the coordinator of the Inflames study, led by CIBER, which seeks to identify the mechanisms involved in the inflammatory processes in the obese, type 2 diabetics, and patients with Crohn’s disease, with the aim to obtain new therapeutic strategies for these diseases.
Read the interview in Diario Médico (in Spanish)
Craig Donoghue, PhD student in the Research Unit on Asymmetric Synthesis at IRB Barcelona, has been interviewed by the Royal Society of Chemistry. Donoghue explains his experience in industry and research, which has led him to appreciate the importance of knowledge transfer from research centres to society. The interview is part of the “175 Faces of Chemistry” series, which commemorates the 175th anniversary of this organisation.
Read the interview in the Royal Society of Chemistry
Radio 5 (RNE) has reported on the “Spark” project, launched by the public-private consortium led by Iproteos, an IRB Barcelona and UB spin-off. IRB Barcelona, CRG, the University of the Basque Country, and the biopharmaceutical company Ascil-Biopharma are also involved in the project. The program includes statements by Javier Meana, researcher at the University of the Basque Country, and Teresa Tarragó, researcher at IRB Barcelona and co-founder of Iproteos.
Listen to the news on Radio 5 (04:30 minutes, in Spanish)
“La Vanguardia” newspaper publishes an interview with Eduard Batlle, ICREA researcher and group leader of the Colorectal Cancer Laboratory at IRB Barcelona, about the article that has led to his nomination for the 2014 “Vanguardia de la Ciencia” Award. Batlle explains how his lab has found that colon has a natural defence mechanism against cancer, a protein called BMP, and the research lines that have emerged from this discovery.
Read the interview in “La Vanguardia” newspaper (in Spanish)
Radio Euskadi interviews Meritxell Teixidó, associate researcher in the Peptide and Protein Laboratory at IRB Barcelona, about the development of a shuttle peptide capable of crossing the blood-brain barrier and carrying therapeutic molecules in to this organ to treat diseases of the central nervous system. In the interview, Teixidó talks about how the shuttle works and about its potential therapeutic applications.
Listen to the interview on Radio Euskadi (10:36 minutes, in Spanish)