Radio 5 (RNE) has broadcasted a report on a molecule developed by IRB Barcelona capable of crossing the barrier that protects the brain and transporting drugs inside. The breakthrough made by the Peptide and Protein Laboratory was recently published in Angewandte Chemie.
Roger Prades, first author of the article and who did his PhD in this lab, and Benjamí Oller, a PhD student in the same lab, explain how this shuttle works. The molecule opens the door to the development of new drugs for diseases that affect the central nervous system, in addition to giving a new opportunity to drugs previously discarded because they are unable reach the brain unaided.
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The business section of “La Vanguardia”, in addition to other media and organizations, have highlighted the Consolidator Grant awarded by the European Research Council (ERC) to the project led by ICREA researcher Xavier Salvatella, head of the Molecular Biophysics Laboratory at IRB Barcelona. The results of this project could lead to new drugs for prostate cancer.
“La Vanguardia” (in Catalan) and...
The “Gaceta Médica” newspaper has published an article about the computational resource dSysMap, developed by the Laboratory of Structural Bioinformatics and Network Biology at IRB Barcelona, led by ICREA researcher Patrick Aloy. The article includes statements by Aloy. This tool, which associates genetic mutations with various complex diseases, was presented in the journal Nature Methods and has been included in the international consortium Pan-Cancer for the analysis of human tumours.
An article in “El Punt Avui” newspaper mentions the most recent advances made by the Peptides and Proteins Laboratory at IRB Barcelona, headed by Ernest Giralt, also full professor at the UB. This lab has identified several substances capable of transporting drugs across the barrier that protects the brain from infections. The article includes statements made by Giralt and explains the projects underway in his lab to find treatments for various neurological diseases and tumours.
Read the article in El Punt Avui (in Catalan)
On Monday, the weekly medical newspaper “Gaceta Médica” reported on the study published in the journal Nature Genetics by the Colorectal Cancer Laboratory at IRB Barcelona, led by ICREA researcher Eduard Batlle. This study associates the alterations caused by colon tumour cells in healthy cells in surrounding tissues, called stroma, with the probability of developing subsequent metastasis.
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“El País” has included an article about Spark, the project started by the public-private consortium led by Iproteos, an IRB Barcelona and UB spin-off. IRB Barcelona, CRG, the University of the Basque Country, and the biopharmaceutical company Ascil-Biopharma are also involved in the project. The article includes statements by Teresa Tarragó, researcher at IRB Barcelona and co-founder of Iproteos, and Miquel Bernardo, director of the Schizophrenia Unit at the Hospital Clínic and main researcher of the Mental Health network CIBERSAM.
Read the article in El País (in Spanish)
The computational tool developed by the Laboratory of Structural Bioinformatics and Network Biology at IRB Barcelona, led by ICREA researcher Patrick Aloy, associates 23,000 genetic mutations with various complex diseases such as cancer, Alzheimer’s and diabetes. The presentation of the dSysMap tool in the journal Nature Methods, and its inclusion in the international consortium Pan-Cancer for the analysis of human tumours have had a considerable impact in the media, among these the “Diari de Girona”.
The work of the Colorectal Cancer Laboratory published in Nature Genetics on the molecular classification of colon tumors has had a great impact on the media. The study shows that the malignancy of tumors lies in whether the cells surrounding the tumor are altered or not. The news highlights the promise that the results hold to develop a diagnostic test to predict the risk of metastasis in patients. Another striking result is the proposal to start clinical trials using inhibitors of an experimental drug that has proven to halt metastasis in mice.
TV3 News has broadcasted a report on a shuttle molecule capable of crossing the barrier that protects the brain from infections and of transporting therapeutic molecules into this organ —a development patented by members of the Peptides and Proteins Laboratory at IRB Barcelona, headed by Ernest Giralt, also full professor at the UB. In the report, Giralt explains how this shuttle works. His lab is already working on the applications of this shuttle in three projects to treat various diseases that affect the brain.
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“El Mundo” has produced an article to mark the publication of 24 papers on epigenetics in journals belonging to the Nature group. These papers are the result of the endeavours of hundreds of scientists participating in the Epigenomics Mapping Programme, launched by the USA National Institutes of Health (NIH) in 2008, and its European equivalent project, called Blueprint Epigenome. The article includes statements by Ferran Azorín, group leader of the Chromatin Structure and Function Laboratory at IRB Barcelona and CSIC research professor.