- Cell and Developmental Biology. Includes gene expression, developmental molecular biology, cell biology, functional genomics and proteomics of cell and embryo development and tissue regeneration.
- Structural and Computational Biology. Includes the structural analysis of macromolecules and their interactions usign a variety of techniques: X-ray, NMR, electron microscopy, macromolecular biophysics, bioinformatics and molecular modelling.
- Molecular Medicine. Includes the molecular bases of metabolic and genetic diseases, the study of diagnostic or therapeutic targets and the functional genomics and proteomics of pathologies and translational research.
- Chemistry and Molecular Pharmacology. Includes the design and synthesis of small molecules and macromolecules, with special emphasis on two aspects of combinatorial chemistry: the building of libraries and optimisation of the production of synthetic compounds, and biotechnologies for molecular selection directed at therapeutic targets and the establishment of the relationship between drugs and their targets.
- Oncology. Includes the study of diverse aspects of tumour initiation and progression, the relationship between stem cells and cancer, and the identification of the programmes that drive tissue-specific metastasis. It comprises a research line directed by Joan Massagué, that will work in coordination with the Cancer Biology and Genetics programme that he chairs at the Memorial Sloan-Kettering Center, in New York.